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Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1

Investigation published in Antimicrobial Agents and Chemotherapy

June 1st, 2007

beta-Lactam resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. Clinical high-level beta-lactam-resistant isolates from Spain bore a novel plasmid, pB1000, expressing a functionally active ROB-1 beta-lactamase. Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000




San Millan A., Escudero JA., Catalan A., Nieto S., Farelo F., Gibert M., Moreno MA., Dominguez L. and Gonzalez-Zorn B..




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Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1

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Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1



Participants:

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Universidad ComplutenseServicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).







Antimicrobial Agents and Chemotherapy
FACTOR YEAR Q
4.390 2007

NLMID: 315061

PMID: 17438055

ISSN: 0066-4804



TITLE: Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1


JOURNAL: Antimicrob Agents Chemother


NUMERACIÓN: 51(6):2260-4


AÑO: 2007


PUBLISHER: American Society for Microbiology


AUTHORS: San Millan A., Escudero JA., Catalan A., Nieto S., Farelo F., Gibert M., Moreno MA., Dominguez L. and Gonzalez-Zorn B..


2nd
José Antonio Escudero García-Calderón
8th
Lucas Domínguez Rodríguez
Last
Bruno González Zorn

DOI: https://doi.org/10.1128/AAC.00242-07


CITE THIS PUBLICATION:

San Millan A., Escudero JA., Catalan A., Nieto S., Farelo F., Gibert M., Moreno MA., Dominguez L. and Gonzalez-Zorn B. Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1. Antimicrobial Agents and Chemotherapy. 51(6):2260-4. 2007. (A). ISSN: 0066-4804. DOI: 10.1128/AAC.00242-07


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