Beta-lactam resistance in Haemophilus parasuis Is mediated by plasmid pB1000 bearing blaROB-1
Investigation published in Antimicrobial Agents and Chemotherapy
June 1st, 2007
beta-Lactam resistance in Haemophilus parasuis is an emerging phenomenon that has not yet been characterized from a molecular perspective. Clinical high-level beta-lactam-resistant isolates from Spain bore a novel plasmid, pB1000, expressing a functionally active ROB-1 beta-lactamase. Pulsed-field gel electrophoresis was applied for the first time to H. parasuis and showed that beta-lactam resistance is due to clonal spread of a resistant strain, BB1018, bearing pB1000
San Millan A., Escudero JA., Catalan A., Nieto S., Farelo F., Gibert M., Moreno MA., Dominguez L. and Gonzalez-Zorn B..
Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). | |
Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |