Home \ Research \ Scientific publications \


Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela

Antimicrobial Agents and Chemotherapy publish this investigation article

September 23rd, 2016

We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal and environmental Enterobacteriaceae from Cumana (Venezuela) collected in 2015. mcr-1 was detected in 2/93 Escherichia coli from swine and human isolates resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes




Delgado-Blas JF., Ovejero CM., Abadia-Patino L. and Gonzalez-Zorn B..




See this article
Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela

See it on NLM PubMed
Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela



Participants:

Universidad ComplutenseServicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Universidad de OrienteDepartment of Biomedicine. Instituto de Investigaciones en Biomedicina y Ciencias Aplicadas. Universidad de Oriente (UDO).







Antimicrobial Agents and Chemotherapy
FACTOR YEAR Q
4.302 2016 1º

NLMID: 315061

PMID: 27431212

ISSN: 0066-4804



TITLE: Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela


JOURNAL: Antimicrob Agents Chemother


NUMERACIÓN: 60(10):6356-8


AÑO: 2016


PUBLISHER: American Society for Microbiology


AUTHORS: Delgado-Blas JF., Ovejero CM., Abadia-Patino L. and Gonzalez-Zorn B..


Bruno González Zorn

DOI: https://doi.org/10.1128/AAC.01319-16


CITE THIS PUBLICATION:

Delgado-Blas JF., Ovejero CM., Abadia-Patino L. and Gonzalez-Zorn B. Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela. Antimicrobial Agents and Chemotherapy. 60(10):6356-8. 2016. (A). ISSN: 0066-4804. DOI: 10.1128/AAC.01319-16


UNITS:

Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA)
Last news of research

Evolutionary Dynamics of Integron Resistance Cassettes. A Deeper Look into the Integron Model

Forensic findings in urban red fox mortality in the metropolitan area of Madrid, 2014-2022

Active surveillance of antimicrobial resistance in companion animals: A pilot study in a Spanish Veterinary Teaching Hospital

Tertiary lymphoid organs in wild boar exposed to a low-virulent isolate of African swine fever virus

Eco-Sanitary Regionalization of Wild Boar (Sus scrofa) in the Western Palearctic Realm as a Tool for the Stewardship of African Swine Fever