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Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela

Antimicrobial Agents and Chemotherapy publica este artículo de investigación

18 de junio de 2016

We studied the presence of the mobile colistin resistance gene mcr-1 in human, animal and environmental Enterobacteriaceae from Cumana (Venezuela) collected in 2015. mcr-1 was detected in 2/93 Escherichia coli from swine and human isolates resistant to colistin. Whole-genome sequencing and transformation experiments identified mcr-1 on an IncI2 plasmid. One of the isolates also bore the widely spread carbapenemase NDM-1. A One Health approach is necessary to further elucidate the flux of these high-risk genes




Delgado-Blas JF., Ovejero CM., Abadia Patino L. y Gonzalez-Zorn B..




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Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela

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Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela


Participantes:

Universidad ComplutenseServicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Universidad de OrienteDepartment of Biomedicine. Instituto de Investigaciones en Biomedicina y Ciencias Aplicadas. Universidad de Oriente (UDO).







Antimicrobial Agents and Chemotherapy
FACTOR YEAR Q
4.302 2016

NLMID: 315061

PMID: 27431212

ISSN: 0066-4804



TÍTULO: Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela


REVISTA: Antimicrob. Agents Chemother.


NUMERACIÓN: 60(10):6356-8


AÑO: 2016


EDITORIAL: American Society for Microbiology


AUTORES: Delgado-Blas JF., Ovejero CM., Abadia Patino L. and Gonzalez-Zorn B..


PARTICIPANTES VISAVET


First
José Francisco Delgado Blas
Last
Bruno González Zorn

DOI: https://doi.org/10.1128/AAC.01319-16


CITA ESTA PUBLICACIÓN:

Delgado-Blas JF., Ovejero CM., Abadia Patino L. y Gonzalez-Zorn B. Coexistence of mcr-1 and blaNDM-1 in Escherichia coli from Venezuela. Antimicrobial Agents and Chemotherapy. 60(10):6356-8. 2016. (A). ISSN: 0066-4804. DOI: 10.1128/AAC.01319-16


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