Comunicación presentada en 17th International Symposium of Veterinary Epidemiology and Economics (ISVEE 17)

12 de noviembre de 2024

Wiederkehr-Bruno CM., Retamal P., Torre-Fuentes L., Ugarte-Ruiz M., Crespo O., Calfucura P. y Alvarez J.

Salmonella enterica, one of the most isolated foodborne pathogens, is capable of infecting multiple species and causes millions of infections annually. The serovar S. Infantis is lately in the spotlight due to the emergence of clones containing a megaplasmid known as pESI (plasmid of emerging S. enterica Infantis) that harbour multiple resistance genes including the extended-spectrum beta-lactamase (ESBL) blaCTX-M-65, which confers resistance to third-generation cephalosporins, antibiotics of choice in cases of extraintestinal infection. blaCTX-M-65-carrying S. Infantis clones have been described in humans and livestock but their distribution in wildlife and the possible role of wild animals in their epidemiology remains unclear. This study describes the circulating Salmonella serovars and their antimicrobial resistance phenotypes and genotypes in Humboldt penguin (Spheniscus humboldti) colonies from two areas with different anthropogenic pressure from Valparaíso Region, in central Chile. A total of 284 faecal samples from penguin nests located in two different locations were collected, four of which were positive for Salmonella by culture. Three isolates from Cachagua Island belonged to S. Infantis serovar, while an isolate from Pájaro Niños Island belonged to S. Give. All the S. Infantis isolates presented an ESBL phenotype, and whole-genome sequencing revealed they carried the megaplasmid pESI encoding the blaCTX-M-65 gene along with many other resistance genes (Table 1). All the S. Infantis strains were closely related with two unidentified shorebird isolates, sampled 115 km away in another study. Although the number of samples limits our ability to determine the most likely source and the transmission routes in the sampled populations, the presence of these multidrug resistance Salmonella clones, especially in protected birds, is of great concern. Knowledge of these transmissions can help to establish better conservation policies under a One Health approach

	Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).
	Facultad de Ciencias Veterinarias. Universidad de Chile.
	Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Enlace a 17th International Symposium of Veterinary Epidemiology and Economics (ISVEE 17)