Noticias de diciembre de 2024
24 de diciembre de 2024
Vía publiDB
Cytokines as potential biomarkers for the diagnosis of Mycobacterium bovis infection in Mediterranean buffaloes (Bubalus bubalis)
Investigación publicada en Frontiers in veterinary science
Mycobacterium bovis (M. bovis) is the primary agent of bovine tuberculosis (TB) in Mediterranean buffalo, which has a negative economic impact on buffalo herds. Improving TB diagnostic performance in this species represents a key step to eradicate efficiently this disease. We have recently shown the utility of the IFN-γ assay in the diagnosis of M. bovis infection in Mediterranean buffaloes (Bubalus bubalis), but other cytokines might be useful immunological biomarkers of this infection. We therefore investigated the utility of key immune cytokines as diagnostic biomarkers of M. bovis inf…
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Noticias relacionadas en otros medios:
- Veterinarios españoles avanzan en el diagnóstico de tuberculosis bovina en búfalos mediterráneos - animalshealth.es
20 de diciembre de 2024
Vía publiDB
African swine fever from Kenya to five continents: the role of wild boar
Revue Scientifique et Technique publica este artículo de investigación
African swine fever (ASF) is currently the largest threat to world pork production. The complexity of the virus, its persistence in the environment, the particular immune response it elicits without significant neutralising antibodies, its capacity for transmission by several routes and the presentation of different clinical forms, from acute with high mortality to attenuated to chronic, all pose significant challenges. This article provides an overview of the epidemiological situation of ASF across five continents, the role of wild boar in virus transmission, the development of new immunologi…
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19 de diciembre de 2024
Vía publiDB
Shaken, not stirred: magnetic bead DNA extraction as a rapid and effective method for the scaling up of bovine tuberculosis diagnosis
BMC Veterinary Research publica este artículo de investigación
Background: The growing use of real-time PCR (qPCR) as a diagnostic method for bovine TB (bTB) requires rapid and effective DNA extraction methods, which are crucial for its success. Automated DNA extraction methods based on magnetic beads are a promising alternative to conventional silica column-based protocols (COL protocol) due to their high throughput capacity and reduced hands-on time. This study aimed to assess the performance of the MagMax CORE Nucleic Acid Purification kit and the KingFisher Flex instrument (KF protocol) as an alternative for scaling up the use of qPCR in bTB diagnosis…
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17 de diciembre de 2024
Servicio de Informática y Comunicación
Felices Fiestas y Próspero Año Nuevo 2025
El Servicio de Vigilancia Sanitaria Equina SEVISEQ protagoniza este año la felicitación del centro VISAVET de la Universidad Complutense de Madrid
…
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15 de diciembre de 2024
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Epidemiological cutoff values and genetic antimicrobial resistance of Lactococcus garvieae and L. petauri
Aquaculture (Amsterdam, Netherlands) publica este artículo de investigación
Lactococcus garvieae and L. petauri are etiological agents of lactococcosis, which cause significant losses in trout aquaculture at elevated water temperatures. Optimizing antimicrobial dosage regimens and identifying the minimum inhibitory concentration (MIC) are important prerequisites for determining clinical breakpoints and effective antimicrobial use. In the present study, epidemiological cutoff values (ECV) were established for 14 antimicrobials using L. garvieae (n = 32) and L. petauri (n = 78), isolated from rainbow trout farms in Türkiye, Spain, Italy, and Greece. The provisional ECVs…
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13 de diciembre de 2024
Vía publiDB
Double Deletion of EP402R and EP153R in the Attenuated Lv17/WB/Rie1 African Swine Fever Virus (ASFV) Enhances Safety, Provides DIVA Compatibility, and Confers Complete Protection Against a Genotype II Virulent Strain
Investigación publicada en Vaccines
Background/Objectives: African swine fever virus (ASFV) is a devastating disease affecting domestic and wild suids and causing significant economic losses in the global pig industry. Attenuated modified live virus (MLV) vaccines are the most promising approaches for vaccine development. This study aimed to evaluate the safety and efficacy of four recombinant ASFV genotype II strains, derived from the non-hemadsorbing (non-HAD) attenuated isolate Lv17/WB/Rie1, through the single or simultaneous deletion of virulence-associated genes. Methods: Recombinant viruses were engineered by deleting the …
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3 de diciembre de 2024
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Seminarios VISAVET 2024
Comunicaciones en este evento:
- Cytokines in viral infections: an update
- Ruido, Memoria y Resistencia a Antibióticos
- Plasmid species and their use in the analysis of the Salmonella accessory genome
- Estudio de candidatos vacunales contra la tuberculosis bovina
- Espectroscopía de RMN de sobremesa: Transformando la Metabolómica Clínica
- Iniciación a las técnicas de cultivo celular
- Exploring Novel Strategies for Detecting and Managing Active and Latent Tuberculosis Infections
2 de diciembre de 2024
Vía publiDB
A high titer antibody response against P22 protein immunocomplex is not correlated with protection in naturally tuberculosis-infected goats
Artículo de investigación publicado en The Veterinary quarterly
Caprine livestock are significant reservoirs of the Mycobacterium tuberculosis complex (MTBC), contributing to tuberculosis (TB) transmission among animals and humans. The P22 protein immunocomplex (P22PI), derived from bovine tuberculin, shows immunostimulating capacity and is used for TB diagnosis. This study assessed the immunogenicity and protective efficacy of P22PI in two groups of goats: 24 naïve goats (12 immunised, 12 controls) from a TB-free herd, and 24 infected goats (12 immunised, 12 controls), referred to as pre-infected animals, from a M. bovis-infected herd. Both were exposed f…
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