Bacterial and host factors implicated in nasal carriage of methicillin-resistant Staphylococcus aureus in mice
Investigación publicada en Infection and Immunity
1 de marzo de 2005
Nasal carriage is a major risk factor for Staphylococcus aureus infection, especially for methicillin-resistant strains (MRSA). Using a mouse model of nasal carriage, we have compared several S. aureus strains and demonstrated increased colonization levels by MRSA in cystic fibrosis transmembrane conductance regulator-deficient mice and Toll-like receptor 2 (TLR2)-deficient mice but not TLR4-deficient mice
Gonzalez-Zorn B., Senna JP., Fiette L., Shorte S., Testard A., Chignard M., Courvalin P. y Grillot-Courvalin C.
Participantes:
 | Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
| Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
 | Unité des Agents Antibactériens. Unité de Recherche et d´Expertise en Histotechnologie et Pathologie. Unité de Défense Innée et Inflammation. Plate-forme d´Imagerie Dynamique. Département de Microbiologie. Institut Pasteur. |
