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Serological technique for detecting tuberculosis prevalence in sheep in Atlantic Spain

Artículo de investigación publicado en Research in Veterinary Science

1 de abril de 2020

Recent studies show that sheep could be considered to be a maintenance host for the causative agents of animal tuberculosis (TB). The performance of diagnostic tests is not well established, and new tests need to be developed for this species. In addition, information about TB prevalence in sheep is scarce. Our objectives were to evaluate a new P22 ELISA for detection of specific antibodies against Mycobacterium tuberculosis Complex (MTC), and to assess the seropositivity in 3998 sheep from herds sampled in TB hotspot areas of northern Atlantic Spain with a low TB prevalence in cattle. Results based on 80 sheep of known infection status suggest excellent sensitivity and specificity (100% and 98%, respectively) even in a M. avium susbsp. paratuberculosis infected flock. The observed TB seroprevalence was 17.96% (698/3998; CI95% 16.31-18.67). Our results indicate that the P22 ELISA may constitute a good option for TB screening at the herd level in sheep, and that sheep are an important host and control programs should be implemented at least in hotspots or when cohabiting with other TB-infected species, i.e. cattle and goats




Infantes-Lorenzo JA., Gortazar C., Dominguez L., Munoz-Mendoza M., Dominguez M. y Balseiro A.




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Serological technique for detecting tuberculosis prevalence in sheep in Atlantic Spain

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Serological technique for detecting tuberculosis prevalence in sheep in Atlantic Spain


Participantes:

Universidad ComplutenseServicio de Micobacterias (MYC). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Gobierno de Castilla-La ManchaSanidad y Biotecnología (SaBio). Instituto de Investigación en Recursos Cinegéticos (IREC). Consejo Superior de Investigaciones Científicas (CSIC). Universidad de Castilla La Mancha (UCLM). Gobierno de Castilla-La Mancha (JCCM).

Xunta de GaliciaXunta de Galicia.

Instituto de Salud Carlos IIIServicio de Inmunología. Centro Nacional de Microbiología (CNM). Instituto de Salud Carlos III (ISCIII).

Universidad de LeónDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad de León.







Research in Veterinary Science
FACTOR YEAR Q
1.751 2018

NLMID: 401300

PMID: 31954320

ISSN: 0034-5288



TÍTULO: Serological technique for detecting tuberculosis prevalence in sheep in Atlantic Spain


REVISTA: Res. Vet. Sci.


NUMERACIÓN: 129:96-98


AÑO: 2020


EDITORIAL: Elsevier


AUTORES: Infantes-Lorenzo JA., Gortazar C., Dominguez L., Munoz-Mendoza M., Dominguez M. and Balseiro A.


PARTICIPANTES VISAVET


Lucas Domínguez Rodríguez

DOI: https://doi.org/10.1016/j.rvsc.2020.01.013


CITA ESTA PUBLICACIÓN:

Infantes-Lorenzo JA., Gortazar C., Dominguez L., Munoz-Mendoza M., Dominguez M. y Balseiro A. Serological technique for detecting tuberculosis prevalence in sheep in Atlantic Spain. Research in Veterinary Science. 129:96-98. 2020. (A). ISSN: 0034-5288. DOI: 10.1016/j.rvsc.2020.01.013


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