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The bla NDM-1 carrying IncA/C2 plasmid underlies structural alterations and co-integrate formation in vivo

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In 2012, a carbapenemase-producing Salmonella (S.) Corvallis carrying a bla NDM-1 multi-resistance IncA/C2 plasmid, apart from IncHI2 and ColE-like plasmids, was detected in a wild bird in Germany. In recent broiler chicken infection study, we observed transfer of this bla NDM-1-carrying IncA/C2 plasmid to other Enterobacteriaceae Here, we focused on the stability of this plasmid and gained insight into type and frequency of its structural alterations after an in vivo passage in a broiler infection study




Hadziabdic S., Fischer J., Borowiak M., Malorny B., Juraschek K., Kasbohrer A., Guerra B., Deneke C., Gonzalez-Zorn B. y Szabo I.




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The bla NDM-1 carrying IncA/C2 plasmid underlies structural alterations and co-integrate formation in vivo

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The bla NDM-1 carrying IncA/C2 plasmid underlies structural alterations and co-integrate formation in vivo

Participantes:

Federal Institute for Risk AssessmentDepartment of Biological Safety. Federal Institute for Risk Assessment (BfR).

European Food Safety AuthorityEuropean Food Safety Authority (EFSA).

Universidad ComplutenseCentro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).







Antimicrobial Agents and Chemotherapy
FACTOR YEAR Q
4.256 2017

NLMID: 315061

PMID: 31109975

ISSN: 0066-4804



TÍTULO: The bla NDM-1 carrying IncA/C2 plasmid underlies structural alterations and co-integrate formation in vivo


REVISTA: Antimicrob. Agents Chemother.


EDITORIAL: American Society for Microbiology


AUTORES: Hadziabdic S., Fischer J., Borowiak M., Malorny B., Juraschek K., Kasbohrer A., Guerra B., Deneke C., Gonzalez-Zorn B. and Szabo I.


PARTICIPANTES VISAVET


Bruno González Zorn

DOI: https://doi.org/10.1128/AAC.00380-19


CITA ESTA PUBLICACIÓN:

Hadziabdic S., Fischer J., Borowiak M., Malorny B., Juraschek K., Kasbohrer A., Guerra B., Deneke C., Gonzalez-Zorn B. y Szabo I. The bla NDM-1 carrying IncA/C2 plasmid underlies structural alterations and co-integrate formation in vivo. Antimicrobial Agents and Chemotherapy. In Press. (A). ISSN: 0066-4804. DOI: 10.1128/AAC.00380-19