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Integron Identification in Bacterial Genomes and Cassette Recombination Assays

The book Horizontal Gene Transfer edited by Humana Press Inc. includes this chapter

October 5th, 2019

Vit C., Loot C., Escudero JA., Nivina A. and Mazel D.


Integrons are genetic elements involved in bacterial adaptation to the environment. Sedentary chromosomal integrons (SCIs) can stockpile and rearrange a myriad of different functions encoded in gene cassettes. Through their association with transposable elements and conjugative plasmids, some SCIs have acquired mobility and are now termed Mobile Integrons (MIs). MIs have reached the hospitals and are involved in the rise and spread of antibiotic resistance genes through horizontal gene transfer among numerous bacterial species. Here we aimed at describing methods for the detection of integrons in sequenced bacterial genomes as well as for the experimental characterization of the activity of their different components: The integrase and the recombination sites





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Integron Identification in Bacterial Genomes and Cassette Recombination Assays



Participants:

Institut PasteurBacterial Genome Plasticity (BGP). Department of Genomes and Genetics. Institut Pasteur. 111

Centre National de la Recherche ScientifiqueUMR3525. Centre National de la Recherche Scientifique (CNRS). 111

Université Sorbonne Paris DescartesCollège doctoral. Université Sorbonne Paris Descartes. 111

Université Sorbonne Paris DescartesUniversité Sorbonne Paris Descartes. 111








CHAPTER: Integron Identification in Bacterial Genomes and Cassette Recombination Assays


TYPE: inBook


AUTHORS: Vit C., Loot C., Escudero JA., Nivina A. and Mazel D.


VISAVET PARTICIPANTS


José Antonio Escudero García-Calderón

BOOK: Horizontal Gene Transfer


EDITION: 1


LANGUAJE: English


ISBN: 978-1-4939-9876-0


NUMERATION: Volume 2075; Pages 189-


DATE: October 5th, 2019


PUBLISHING COMPANY: Humana Press Inc.


DOI: https://doi.org/ 10.1007/978-1-4939-9877-7_14


CITE THIS PUBLICATION:

Vit C., Loot C., Escudero JA., Nivina A. and Mazel D. Integron Identification in Bacterial Genomes and Cassette Recombination Assays.. Volume 2075; Pages 189-. Horizontal Gene Transfer. Ed. 1. Humana Press Inc.. ISBN: 978-1-4939-9876-0. 2019. (inBook)