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Last research news
November 21st, 2025
Vía publiDB
Risk Mapping of African Swine Fever in Domestic Pigs and Wild Boars to Enhance Management and Surveillance in Asia
Transboundary and Emerging Diseases publish this investigation article
African swine fever (ASF) is a highly lethal disease affecting domestic pigs and wild boars, caused by the ASF virus (ASFV), which has rapidly spread across Asia in recent years. In this region, most reported ASF cases involve domestic pigs, while cases in wild boars remain notably lower except in a few countries. However, factors such as the high population of wild boars, limited wildlife surveillance, and inadequate farm biosecurity suggest that the prevalence and transmission of ASFV between these hosts may be underestimated. Therefore, we used a simplified multicriteria approach (SMCA) to …
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November 14th, 2025
Vía publiDB
Antibiotic Resistance to Critically Important Antimicrobials and Virulence Genes in Enterococcus faecalis Strains Isolated from Eurasian Griffon Vultures (Gyps fulvus) and Their Association with Mobile Genetic Elements
Investigation article published in Veterinary sciences
The phenotypic resistance of 56 Enterococcus faecalis isolates from Eurasian griffon vultures was subjected to surveillance testing with the microdilution method using a standardized panel of antimicrobials. Isolates were also characterized by MLST. Additionally, the genome of 19 isolates with phenotypic resistance to linezolid, ciprofloxacin, chloramphenicol and/or high-level resistance to gentamicin were sequenced to determine their antimicrobial resistance (ARGs) and virulence-associated genes and to identify mobile genetic elements (MGEs). Most isolates (82.1%) exhibited non-wild-type phen…
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November 12nd, 2025
Vía publiDB
Evaluation of serological assays for intra vitam diagnosis of bovine tuberculosis in water buffalo (Bubalus bubalis)
Investigation published in Frontiers in Microbiology
Introduction: Bovine tuberculosis (TB) in water buffalo (Bubalus bubalis) is primarily diagnosed using intra vitam tests, as the intradermal tuberculin test (IDT) and the interferon-gamma release assay (IGRA), both of which detect cell-mediated immunity (CMI). However, a subset of infected animals fails to mount a detectable CMI response, posing a significant risk of undetected transmission. Serological tests assessing the humoral immune response could provide a valuable complementary tool for identifying infected animals that escape detection through traditional CMI-based assays.
Methods: Th…
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November 12nd, 2025
Vía publiDB
Persistent multispecies dissemination of armA-carrying IncR plasmids among clinical and environmental bacterial populations in a Spanish veterinary hospital
Investigation article published in Journal of Clinical Microbiology
Aminoglycoside resistance mediated by 16S rRNA methyltransferases poses a growing threat in both human and veterinary medicine. Here, we conducted a retrospective genomic study of Enterobacterales isolates (n = 789) collected from clinical samples at a veterinary teaching hospital in Spain between 2011 and 2020. We identified four high-level aminoglycoside-resistant ST171 Enterobacter hormaechei subsp. xiangfangensis isolates carrying the armA gene, all from horses. Using Illumina and Nanopore sequencing, we determined that armA was located on a 70 kb IncR plasmid, also carrying other resistan…
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November 11st, 2025
Vía publiDB
A time-space Bayesian regression model of rabies cases in the animal population of Kazakhstan (2013-2023)
Frontiers in veterinary science publish this investigation article
Despite its endemic status and socioeconomic impacts, the spatial-temporal variation in rabies risk and its underlying determinants in Kazakhstan animal populations remain poorly understood. This study aimed to characterise the time-space dynamics of rabies in animal populations across Kazakhstan regions from 2013 to 2023 and identify the key drivers of transmission. Using a Bayesian hierarchical regression model with spatial and temporal random effects, we analysed national surveillance data on rabies cases in livestock, companion animals, and wildlife, alongside sociodemographic and animal p…
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November 4th, 2025
Vía publiDB
Protective effect of heat-inactivated Mycobacterium bovis applied intramuscularly is associated with enhanced lung immune response in caprine tuberculosis
Investigation published in Veterinary Research
Caprine tuberculosis (TB) causes a zoonotic disease with significant economic and health implications. However, excluding some regions, goat herds are not subjected to official TB eradication programs. Implementing vaccination protocols for this species could provide a complementary and effective control strategy against TB. We assessed the protective efficacy and immune response associated with a heat-inactivated Mycobacterium bovis (M. bovis)-based immunostimulant (HIMB) applied intramuscularly against caprine pulmonary TB on 20 kid goats (10 immunized, 10 controls) naturally exposed to M. c…
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November 1st, 2025
Vía publiDB
Attributable sources of the five most prevalent non-typhoidal Salmonella serovars across ten European countries
Investigation published in The Journal of infection
Non-typhoidal Salmonella is the second most frequently reported zoonotic pathogen in the European Union and European Economic Area. Most human infections are caused by serovars Enteritidis and Typhimurium. Genomic characterisation of Salmonella isolates from humans and animals has become a routine public health surveillance tool in many countries. In this study, the relative contributions of several potential sources of human infection of the five frequently reported Salmonella serovars was estimated using machine-learning methods based on a large, cross-sectional collection of genomes from hu…
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November 1st, 2025
Vía publiDB
Diving Into the Depths: Unveiling the Main Etiologies of Piscine Lactococcosis With a Novel Multiplex qPCR Assay
Investigation published in Journal of Fish Diseases
Piscine lactococcosis poses a significant threat to a wide range of cultured and wild fish populations worldwide, typically presenting as acute haemorrhagic septicemia with high morbidity and mortality. Although Lactococcus garvieae was historically considered the sole causative agent of piscine lactococcosis, recent studies have identified L. petauri and L. formosensis as additional, highly pathogenic species. In this study, we developed a novel TaqMan-based multiplex qPCR assay for the simultaneous detection and differentiation of L. garvieae, L. petauri and L. formosensis, following a pange…
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October 28th, 2025
Vía publiDB
Healthcare-related transmission of mobile genetic elements co-carrying blaNDM and 16S rRNA methyltransferase genes in multiple Enterobacterales
Microbial Genomics publish this investigation article
Aminoglycosides are used in the treatment of serious infections with Gram-negative bacteria, especially those resistant to beta-lactams and carbapenems. 16S rRNA methyltransferases (16S-RMTase) are capable of conferring resistance to nearly all aminoglycosides. They are sometimes detected in combination with bla NDM. This study describes the mobile genetic elements associated with bla NDM and 16S-RMTase (co-)carriage in Enterobacterales from Ireland in the period 2019-2023. All isolates (n=58) carrying both bla NDM and a 16S-RMTase gene between 2019 and 2023 were obtained from the CPE National…
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October 24th, 2025
Vía publiDB
WiBISS: a tool to estimate avoided lost revenue of African swine fever wild boar vaccination at municipality level
Frontiers in veterinary science publish this investigation article
This study introduces the WiBISS model, a simulation tool designed to assess the economic and epidemiological impact of a hypothetical African Swine Fever (ASF) vaccination in wild boar in Northern Italy. Using real ASF outbreak data from January 2022 to June 2024, the model evaluates how prompt vaccination could reduce disease spread and economic losses. WiBISS integrates three modules: vaccination simulation, restriction zone estimation, and economic impact analysis. The first two use custom-built cellular automata (CA) in Python and ArcGIS Pro, modeling each ASF case as a cell that can be i…
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