Research

Exploiting 16S rRNA-based metagenomics to reveal neglected microorganisms associated with infertility in breeding bulls in Spanish extensive herds

Research in Veterinary Science publish this investigation article

Bovine infectious infertility represents a problem due to the high impact on animal production and, in many cases, in public health. A lack of information on the characteristics of the bacterial population of the bovine reproductive system can hamper a comprehensive understanding of reproductive pathologies and the role that the microbiome could play. A metagenomic study based on the V3-V4 hypervariable region of the bacterial 16S rRNA gene was performed in 1029 preputial samples from bulls raised in an extensive regimen in Spain (944 from herds with low fertility rates -case group-, and 85 sa… Leer más

Identifying high-risk areas for dog-mediated rabies using Bayesian spatial regression

Investigation article published in One Health

Despite ongoing control efforts, rabies remains an endemic zoonotic disease in many countries. Determining high-risk areas and the space-time patterns of rabies spread, as it relates to epidemiologically important factors, can support policymakers and program managers alike to develop evidence-based targeted surveillance and control programs. In this One Health approach which selected Thailand as the example site, the location-based risk of contracting dog-mediated rabies by both human and animal populations was quantified using a Bayesian spatial regression model. Specifically, a conditional … Leer más

Animal abuse in Spanish-breed fighting cocks (Gallus gallus domesticus)

Investigation article published in Forensic Science International

Cockfighting is illegal both in the European Union and the United States, although fighting cock husbandry and breed preservation are allowed. Here, we describe the pathological findings observed in the carcasses of two Spanish-breed fighting cocks submitted to our laboratory after an animal abuse-suspected death. The postmortem examination revealed these cocks may have been used for cockfighting (comb, ear lobes, wattles, and chest feather removal; and trimmed spurs). The severe extensive hemorrhages observed in the cervical region of both birds, affecting C1-C4 in bird No. 1 and C8-C11 in No… Leer más

Determination of reference intervals of haematological, biochemical and oxidative stress parameters in horses residing in equestrian centers in central Spain

PhD Thesis defense by Aránzazu Buendía Andrés at the Faculty of Veterinary Medicine of the Complutense University of Madrid

Currently, one of the main areas of the equine sector in Spain is the use of the horse for pleasure and sports competition purposes at equestrian centres1. The equine veterinary clinician develops an essential role in the health surveillance of these horses and one of the most frequent tools is the completion of clinical analysis. For the correct interpretation of these analysis, reference intervals, defined by the range of values of an analyte from a population with a defined health status, are necessary. To date, the equine population living in equestrian centres at central Spain did not… Leer más

Intestinal T-cell lymphoma in an Asian small-clawed otter: case report and literature review of lymphoma in the subfamily Lutrinae

Investigation article published in Journal of Veterinary Diagnostic Investigation

The Asian small-clawed otter (Aonyx cinereus) is an endangered species that is common in zoologic collections. A 17-y-old female Asian small-clawed otter under human care, with a clinical history of chronic renal disease, was euthanized because of deteriorating health. Histologically, the jejunal wall was infiltrated by a monomorphic population of small neoplastic lymphocytes that expanded the lamina propria of the villi and crypts, and on rare occasions invaded the submucosa. The tumor was composed of T cells (CD3+) with a proliferation index of 16%. Based on the World Health Organization (WH… Leer más

Effect of a recent parenteral dexamethasone and ketoprofen administration on the immunological diagnosis of tuberculosis in goats

Investigation published in Frontiers in veterinary science

Caprine tuberculosis (TB) is a zoonosis caused by members of the Mycobacterium tuberculosis complex (MTBC). Caprine TB eradication programmes are based mainly on intradermal tuberculin tests and slaughterhouse surveillance. Different factors may affect the performance of the TB diagnostic tests used in caprine herds and, therefore, their ability to detect infected animals. The present study evaluates the effect of the fraudulent administration of two anti-inflammatory substances, dexamethasone and ketoprofen, on the performance of the TB diagnostic techniques used in goats, as well as the suit… Leer más

P22 protein complex in the serodiagnosis of animal tuberculosis: Antigenic stability and cross-reactivity with Corynebacterium pseudotuberculosis infection

Comparative Immunology, Microbiology and Infectious Diseases publish this investigation article

The P22 ELISA was recently developed for the serodiagnosis of animal tuberculosis. Herein, the stability of the P22 antigen in different presentations and storage conditions, and the cross-reactivity with Corynebacterium pseudotuberculosis infection in small ruminants were evaluated. For the stability assay, serum samples from cows, sheep, goats, alpacas, badgers, and wild boar were used in the P22 ELISA. The cross-reactivity analysis used sera from sheep and goats with caseous lymphadenitis (CLA). Differences in the immune recognition of P22 were found when the antigen was stored at 40 °C, bu… Leer más

A subunit vaccine candidate based on the Spike protein of SARS-CoV-2 prevents infectious virus shedding in cats

Investigation published in Research in Veterinary Science

Of the numerous animal species affected by the SARS-CoV-2 virus, cats are one of the most susceptible, and cat-to-cat transmission has been described. Although cat-to-human infection has not, as yet, been demonstrated, preventive measures should be taken in order to avoid both viral infection in cats and transmission among them. In this respect, the application of an effective vaccine to at-risk populations would be a useful tool for controlling the disease in this species. Here, we test a new vaccine prototype based on the Spike protein of the virus in order to prevent infection and infectiou… Leer más

- ¿Lista vacuna contra el coronavirus para animales? - venezuela-news.com

- Una vacuna experimental contra el Covid resulta eficaz en sus primeros ensayos en gatos - ondacero.es

- Una vacuna experimental contra la Covid en gatos resulta eficaz en sus primeros ensayos - 20minutos.es

- Una vacuna experimental de la covid-19 resulta eficaz en sus primeros ensayos en gatos - agenciasinc.es

- Un prototipo vacunal frente al SARS-CoV-2 resulta eficaz en sus primeros ensayos en gatos - ucm.es

- Desarrollan un prototipo de vacuna del covid para gatos - elperiodico.com

- Sviluppano un prototipo di vaccino contro il covid per i gatti - stopandgo.tv

- Prototype covid vaccine developed for cats - royalsblue.com

- Vacuna contra covid-19 fue probada con éxito en animales - eltelegrafo.com

- Prueban con éxito una vacuna contra la covid para animales - epe.es

- Prueban con éxito vacuna contra Covid-19 en animales - elcapitalino.mx

- Prueban con éxito una vacuna contra el Covid para animales - elmundo.es

- Veterinarios españoles desarrollan un prototipo vacunal eficaz frente al Covid-19 en gatos - animalshealth.es

- ¿Vacuna del COVID-19 para mascotas? Este es el resultado de un estudio en gatos - telemundonuevainglaterra.com

- Prueban con éxito vacuna contra coronavirus para animales - acn.com.ve

- Vacuna contra el Covid para gatos tuvo exitosos resultados: podría prevenir mutaciones del virus - biobiochile.cl

- Prueban con éxito vacuna contra el Covid-19 para animales - radioytvmexiquense.mx

- Prueban con éxito vacuna contra el coronavirus en animales - agenciapi.co

- They successfully tested a vaccine against the coronavirus for animals - nationworldnews.com

- Prueban con éxito una vacuna contra el COVID-19 para animales - noticieros.televisa.com

- ¿Vacuna del COVID-19 para mascotas? Este es el resultado de un estudio en gatos - telemundo47.com

- Una vacuna es eficaz para evitar la transmisión covid de gatos a humanos - redaccionmedica.com

- Prueban con éxito una vacuna contra el coronavirus para animales - heraldo.es

- Una vacuna contra la COVID-19 de la Universidad Complutense, eficaz en gatos - infosalus.com

- Prueban con éxito una vacuna contra el coronavirus para animales - rtvc.es

- Prueban con éxito una vacuna contra el coronavirus para animales - forbes.com

- Prueban con éxito una vacuna contra el coronavirus para animales - lavanguardia.com

- Veterinarios españoles desarrollan un prototipo vacunal eficaz frente al Covid-19 en gatos - animalshealth.es

- Prueban con éxito vacuna contra Covid para animales - quierotv.mx

Increasing the data on elasmobranch plasma protein electrophoresis: electrophoretogram reference values determination in the undulate skate (Raja Undulata) and the nursehound shark (Scyliorhinus stellaris) maintained under human care

Investigation article published in BMC Veterinary Research

Background: This study determined plasma protein electrophoresis (PPE) reference intervals in two elasmobranch species: the undulate skate (Raja undulata) and the nursehound shark (Scyliorhinus stellaris), using a reference population of 48 undulate skates (27 males, 21 females) and 62 nursehounds (32 males, 30 females), considered to be clinically healthy. Plasma samples were analyzed using capillary zone electrophoresis (CZE). Results: The undulate skate electrophoretogram resembled those previously reported in other batoids and could be divided into seven consistent fractions. No statistic… Leer más

Antimicrobial resistance and One Health

Revista espannola de quimioterapia publish this investigation article

Antimicrobial resistance is one of the major health problems we face in the 21st century. Nowadays we cannot understand global health without the interdependence between the human, animal and environmental dimensions. It is therefore logical to adopt a "One Health" approach to address this problem. In this review we show why a collaboration of all sectors and all professions is necessary in order to achieve optimal health for people, animals, plants and our environment… Leer más