Research

Assessment of the sensitivity of the bovine tuberculosis eradication program in a high prevalence region of Spain using scenario tree modeling

Investigation published in Preventive Veterinary Medicine

In spite of the efforts invested to eradicate bovine tuberculosis (bTB) in cattle, the disease is still present in several developed countries, including Spain. Among the factors related with disease persistence in high prevalence areas, the lack of sensitivity of the screening test for detection of infected herds [single intradermal tuberculin (SIT) test] can play a major role. Here, a scenario tree model mimicking the diagnostic test scheme in place in the region of Castilla y Leon (Spain) was developed to estimate the probability of detecting bTB in an infected-non detected officially tuber… Leer más

Epidemiological and molecular analysis of the main pathogens of Apis mellifera and their importance in triggering colony losses

Sandra Barroso Arévalo defended the PhD Thesis at the Faculty of Veterinary Medicine of the Complutense University of Madrid

The number of honey bees has been in constant and progressive decline since the second half of the twentieth century. These insects play a key role as pollinators and in the maintenance of global biodiversity. Colony losses include two kind of phenomena. The first one is “Colony collapse disorder” (CCD), which consists of a rapid decrease in bee population, but honey/breeding/pollen stores remain adequate and bees do not show disease symptoms. The second one is winter mortality after wintering. In addition to the impact on the beekeeping sector, colony losses also affect food production, envir… Leer más

Diarrheagenic Escherichia coli Pathotypes From Children Younger Than 5 Years in Kano State, Nigeria

Frontiers in Public Health publish this investigation article

Diarrheagenic Escherichia coli (DEC) is one of the leading causes of gastrointestinal disorders worldwide and an important public health challenge. DEC infection is often underdiagnosed during routine microbiological analysis, especially in resource constrained settings; the use of molecular tests could however help to determine the distribution of DEC and its clinical significance. Here, a study to assess the prevalence of DEC in clinical samples from patients <5 years attending three hospitals in Kano state, Nigeria, was carried out. Samples from 400 patients and 50 controls were collected a… Leer más

Modelos animales para el estudio de la ecología de las resistencia a antibióticos

Gabriel Moyano Ortega defended the PhD Thesis at the Faculty of Veterinary Medicine of the Complutense University of Madrid

El proyecto innovador para el diagnóstico precoz y control eficaz de la tuberculosis en ganadería extensiva y fauna silvestre da sus primeros pasos

El grupo operativo supraautonómico “tuberculosis”, celebra una nueva reunión

Los miembros del Grupo Operativo Supraautonómico “Tuberculosis” han mantenido un encuentro en Madrid para continuar trabajando en la ejecución del Proyecto titulado “Aplicación de medidas innovadoras en el diagnóstico precoz y control eficaz de la tuberculosis en ganadería extensiva y fauna silvestre”
El proyecto, coordinado por la Fundación Artemisan, cuenta entre sus miembros con representantes tanto del ámbito ganadero como del sector cinegético y un presupuesto a dos años de más de 400.000 €. Entre las entidades participantes se encuentran la Asociación Nacional de Jóvenes Agricultores (ASAJA), la Federación Española de Ganado Autóctono y Selecto (FEAGAS), APROCA Castilla la Mancha y APROCA Extremadura, la Asociación Interprofesional de la Carne de Caza (ASICCAZA), el Instituto de Investigación en Recursos Cinegéticos (IREC) de la Universidad de Castilla la Mancha y el Centro de Vigilancia Sanitaria (VISAVET) de la Universidad Complutense de Madrid.  Además, colaboran la S.C.A Ganadera Del Valle de los Pedroches (COVAP), la Unión Nacional de Ganaderos de Vacas Nodrizas (UGAVAN), la Federación Española de la Dehesa (FEDEHESA) y la Real Federación Española de Caza (RFEC). El objetivo principal es aplicar innovación para mejorar la salud, rentabilidad y sostenibilidad de la ganadería extensiva y del subsector cinegético en España, particularmente en relación con la tuberculosis animal y se apoya en acciones de diagnóstico ambiental de los agentes causales de la enfermedad y aplicación de medidas de gestión práctica encaminadas a su control. Además, cuenta con un importante componente formativo e informativo que permitirá a ganaderos y gestores disponer de los conocimientos necesarios para contribuir a reducir la presencia de tuberculosis en sus explotaciones. El proyecto, que pretende ser un referente en los próximos años en el ámbito de la sanidad animal, tanto ganadera como de fauna silvestre, por aportar una visión integral innovadora en la gestión de la enfermedad, se planteó ante la convocatoria por parte del Ministerio de Agricultura, Alimentación y Medio Ambiente de ayudas para proyectos innovadores a ejecutar por Grupos Operativos (GO) supra- autonómicos de la Asociación Europea para la Innovación (AEI-Agri), dentro del Programa Nacional de Desarrollo Rural 2014-2020 (FEADER) para el año 2019. Esta Asociación Europea para la Innovación en materia de productividad y sostenibilidad agrícola (AEI-agri) se apoya por el segundo pilar de la Política Agraria Común (PAC) a raíz de la reforma de 2013, de acuerdo con el Reglamento (UE) n.º 1305/2013, del Parlamento Europeo y del Consejo del 17 de diciembre de 2013, relativo a la ayuda al desarrollo rural a través del Fondo Europeo Agrícola de Desarrollo Rural (FEADER).… Leer más

Selective Persulfide Detection Reveals Evolutionarily Conserved Antiaging Effects of S-Sulfhydration

Cell metabolism publish this investigation article

Life on Earth emerged in a hydrogen sulfide (H2S)-rich environment eons ago and with it protein persulfidation mediated by H2S evolved as a signaling mechanism. Protein persulfidation (S-sulfhydration) is a post-translational modification of reactive cysteine residues, which modulate protein structure and/or function. Persulfides are difficult to label and study due to their reactivity and similarity with cysteine. Here, we report a facile strategy for chemoselective persulfide bioconjugation using dimedone-based probes, to achieve highly selective, rapid, and robust persulfide labeling in bio… Leer más

Effects on Intestinal Mucosal Morphology, Productive Parameters and Microbiota Composition after Supplementation with Fermented Defatted Alperujo (FDA) in Laying Hens

Antibiotics publish this investigation article

The olive oil sector is currently adapting its traditional function to also become a supplier of high-value by-products that possess antioxidant, anti-inflammatory and antimicrobial properties. In this study, we evaluated the effect of the fermented defatted alperujo (FDA) on the intestinal health of laying hens. The morphology of the duodenal and cecal mucosa, the composition of the intestinal microbiota and the productivity of a batch of laying hens were evaluated after FDA supplementation. At early life stages, significant differences (p < 0.001) were observed in duodenal villi height and … Leer más

Coffee Silverskin Extract: Nutritional Value, Safety and Effect on Key Biological Functions

Nutrients publish this investigation article

This study aimed to complete the scientific basis for the validation of a coffee silverskin extract (CSE) as a novel food ingredient according to European legislation. Nutritional value, safety, effects on biochemical biomarkers and excretion of short chain fatty acids (SCFAs) in vivo of CSE were assessed. Proteins, amino acids, fat, fatty acids, fiber, simple sugars and micronutrients were analyzed. For the first time, toxicological and physiological effects were evaluated in vivo by a repeated-dose study in healthy Wistar rats. Hormone secretion, antioxidant (enzymatic and no-enzymatic) and … Leer más

New strategies for the control and eradication of African swine fever

PhD Thesis defense by Cristina Jurado Díaz at the VISAVET Centre of the Complutense University of Madrid

African swine fever, ASF, is one of the notifiable infectious diseases of swine that causes greater sanitary and economic impact. Currently, its relevance is increasing due to disease presence in Africa, Asia and Europe. This doctoral thesis is entitled new strategies to control and eradicate African swine fever, and aims at developing new tools and epidemiological knowledge to prevent, control and eradicate ASF globally. Thus, the most relevant characteristics of the disease and its related risks were explored within the framework of three different scenarios, endemic scenario focused on Sard… Leer más

- Dedica su tesis a las nuevas estrategias para erradicar la peste porcina africana - animalshealth.es

- Nuevas estrategias para el control y erradicación de la peste porcina africana - diarioveterinario.com

Serological, molecular and hematological diagnosis in horses with clinical suspicion of equine piroplasmosis: pooling strengths

Investigation article published in Veterinary Parasitology

Equine piroplasmosis (EP) is a tick-borne protozoan disease caused by Theileria equi and/or Babesia caballi. Clinical signs (fever, pale mucosal membranes, jaundice), anemia and hyperbilirubinemia have been associated with the disease. EP is widespread, has a significant economic impact on the equine industry and remains endemic in Spain. This study was carried out with samples belonging to 140 horses residing in Spain and showing common clinical signs of EP. A blood smear microscopic examination and a comparison between the different results obtained by competitive Enzyme-Linked Immunosorbent… Leer más