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Research lines

New strategies for diagnosis and control of bovine, ovine and caprine brucellosis

Analysis of new approaches for the control of animal brucellosis using available vaccines, and evaluation of current strategies for disease control. Development of new tools for early detection of the pathogen using molecular techniques....

New diagnostic methods design

Development of new dignostic molecular methods based in the Methagenomics and PCR metodologies multiple and quantitative for several animal infectius deseases, in order to be able to carry out molecular epidemiology studies and develop techniques to differentiate vaccinated animals from infected.

Preventive medicine

Development of different epidemiological models on the risks of entry different infectious diseases in our country, by identifying the critical points of each disease and modelling their potential spread. The diseases being studied are classified in the list of notifiable to the World Organization for...

Marine animal health

The project Marine Animal Health has as main objectives the evaluation, monitoring and improving of health in the marine fauna of the Mediterranean Sea, contributing to conservation of the marine ecosystem....

Diagnosis of Q fever in livestock and wildlife using direct and indirect tests.

Analysis of clinical samples by means of direct (real-time PCR direct detection) and indirect (serological tests, IFN-gamma detection assay) diagnostic techniques to assess the distribution of Coxiella burnetii on the animal reservoir and to determine the immune response induced in infected animals.

Diagnosis of swine brucellosis

Use of immunological diagnostic tests (detection of specific antibodies using rose bengale test and ELISA, experimental use of interferon-gamma detection assays) and bacteriology for the detection of infections caused by Brucella suis in swine and in wild boar....

Epidemiological surveillance of zoonotic tick-borne pathogens

Identification of ticks from domestic animals and wildlife and molecular detection of pathogens (genus Erlichia, Borrelia, Anaplasma, Francisella, Coxiella, Rickettsia y Bartonella) by PCR. Use of molecular techniques for identification of tick-borne pathogens at the species-lev...

Design of methods for detection of biological threat agents

Development of systems for direct and indirect detection of bacterial, fungal and plant toxins....

Tuberculosis diagnosis

Improvement and optimization of techniques for the diagnosis of tuberculosis in cattle and other animal species. Study of the immune response against tuberculosis....

Molecular epidemiology of tubeculosis

Epidemiological studies based on molecular characterization data of M. tuberculosis complex members....

Tuberculosis control

Experimental and field studies using vaccination for the control of tuberculosis in domestic and wild animals....

Molecular characterizacion studies of the Mycobacterium avium complex

Molecular studies of the members included within the Mycobacterium avium complex....

Diagnosis of other mycobacteriosis

Diagnosis of other mycobacteria not included in the complexes M. tuberculosis and M. avium....

Clinical diagnosis

One task that has always demanded great attention by our group, both from the point of views of teaching and research is that related with animal diseases. This line of work has been a huge boost from the beginning, doing continued efforts to deepen the knowledge of the different pathogens involved in...

Bacterial taxonomy

Traditional systems of bacteriological diagnosis are sometimes not sufficient to achieve a definitive identification of the etiological agent. As a result, certain pathogens may be misidentified or unidentified. In these circumstances, it is advisable the use of alternatives to traditional techniques....

Molecular typing

The epidemiological study of infectious diseases is used to determine the clonal relationship between various isolates of the same bacterial species. Different techniques can be used to distinguish and classify strains of a given bacterial species. This discrimination at the strain level is useful for...

Antimicrobial resistances in pathogens, food-borne zoonotic agents and indicators

Annual surveillance programs in Antimicrobial resistance are established. Microorganisms are obtained in active sampling conducted in collaboration with the Central Administration, Regional Administration and pharmaceutical companies. Clinical isolates are performed with bacterial collections.&nb...

Foodborne zoonoses in animals and meat, eggs and other products from animal origin intended for human consumption, mainly Salmonella spp. Campylobacter spp., Verotoxigenic Escherichia coli and Yersinia enterocolitica

Annual surveillance programs of zoonoses agents are established. Microorganisms are obtained in active sampling conducted in collaboration with different Administrations. Besides, research programs are performed to improve control programs of zoonotic agents. Additionally, the presence of these m...

Genetic characterization of antimicrobial resistance

Isolates that show a resistance phenotype of interest to public health or animal health, are analyzed in depth using molecular techniques (molecular detection, Next Generation Sequencing, etc.)....

Genetic characterization of microorganisms populations

Different isolates are compared by genetic techniques (Pulsed Field Gel Electrophoresis, spa-typing, Multi Locus Sequence Typing,Next Generation Sequencing, etc.)...

Diagnosis of leishmaniasis in the animal reservoir

Research on the epidemiology of leishmaniasis in peri-urban settings. Identification of potential atypical reservoirs of  Leishmania.  Diagnosis of infection using indirect (indirect inmunofluorescence assay) and direct (PCR) techniques in biological samples from different hosts and vectors<...

Proliferative and non proliferative lesions of the gastrointestinal tract in small animals

Our participation in Gastrointestinal Course supervised by Dr. I. van der Gaag and Liver Pathology leaded by T. van den Ingh at the University of Utrecht (Netherlands), we started in this line of research. As a resulting investigations have been realized three PhD dissertations and numerous scientific...

Immunopathology of tuberculosis in domestic and wild animals

Our colaboration  in European in the pathological aspects with Reference Laboratory on Bovine Tuberculosis began our journey in this research. Since then I have worked in the description of many pathological processes induced by different strains of Mycobacterium, both domestic and wild animals. ...

Malditof profiling and imaging

The first applications of mass spectrometry in clinical were as a method adapted to highly complex protein sample analysis in laboratories pathobiology, using high levels of sensitivity and specificity in the diagnosis of tumor processes, and other hereditary disorders markers of pathology. To...

Forensic Veterinary

As part of the Veterinary Pathology, increasingly there are many cases of animal abuse and natural disasters that require accurate and specific description of the process. For this reason, in recent years we have focused in particular on developing a specific methodology, which departs from the routin...

Fish pathology

In recent years, parallel to the development of aquaculture and intensive production has been a rise in infectious diseases, some of which have been major losses. Our work in this field has been to make a correct diagnostic pathology and microbiological isolation to take appropriate preventive measure...

Integrated monitoring and control of Toxoplasma gondii and Hepatitis E virus in food supply chains

The main objective of this project is to characterize the presence of emerging food-borne pathogens (in particular Toxoplasma gondii and hepatitis E virus) along the food chain, from the origin to the point of sale of the product. This project will provide a new framework for the monitoring, ...

Molecular characterization of human reservoirs potentially pathogenic Escherichia coli, animal and environmental

Characterization of potentially pathogenic E. coli samples from different origins....

Genetic characterization of Campylobacter

Genetic characterization of Campylobacter jejuni and coli strains from different origins (animal, food and urban effluents)....

Modification of intestinal microbiota, Healthy Gut

An approach based on the use of natural compounds for the control of zoonotic or resistant bacteria....

Application of MALDI-TOF technique in the clinical microbiology and Agri-food field

MALDI-TOF technique has been traditionally used for proteomics studies, mainly, for the identification and characterization of proteins of interest. Recently, this analitycal technique has been demonstrated to be useful in the microbiology field not only for identification but also for chara...

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