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Last scientific dissertations

July 27th, 2021

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Mª Victoria Ortega García

Detection of Leishmania spp. in atypical reservoirs and molecular characterisation

PhD Thesis defense by Mª Victoria Ortega García at the Faculty of Veterinary Medicine of the Complutense University of Madrid


Leishmaniasis is a group of parasitic diseases of zoonotic and anthroponotic origin caused by protozoa of the genus Leishmania, within the Trypanosomatidae family. Transmission to the vertebrate host occurs through the bite of female sandfly, blood-sucking insects belonging to the genera Phlebotomus (Old World) or Lutzomyia (New World), within the Psychodidae family. Among the parasitic diseases, leishmaniasis ranks second as the most frequent cause of death in the world behind malaria. In addition, this disease is included in the group of neglected tropical diseases (NTD), and is present in m… Leer más



July 16th, 2021

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Raul Manjavacas Pintado

Estudio anatomopatológico y de PCR de la infección por el virus de la mixomatosis y sus variantes en liebre y conejo

Raul Manjavacas Pintado defended this Degree Final Project


Myxomatosis is a characteristic viral disease of rabbits caused by classical Myxoma virus (MYXV), a leporipoxvirus introduced in Europe in the 1950s classically affecting European rabbits (Oryctolagus cuniculus) and causing high lethality. However, in 2018 Iberian hares (Lepus granatensis) from Spain exhibited symptoms compatible with myxomatosis. In the wake of this outbreak, a new recombinant strain of Myxoma virus (MYXV-Tol) was identified. In order to study the distribution of these two variants and their involvement in pathology, 14 animals (8 rabbits and 6 hares) from Madrid and Castilla… Leer más



July 15th, 2021

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Carlos Neila Mota

Estudio histopatológico e inmunohistoquímico de las proteínas de matriz extracelular (fibronectina, colágeno I y colágeno III) en la tuberculosis caprina (Mycobacterium caprae)

Degree Final Project defended by Carlos Neila Mota


La lesión resultante de la interacción entre Mycobacterium y la respuesta inmunitaria del hospedador es el granuloma tuberculoso, una estructura altamente compleja, dinámica, compacta, avascular e hipóxica cuya función es contener y neutralizar la infección por micobacterias en el tejido. Los granulomas tuberculosos, excepto en fases incipientes, están característicamente parcial o totalmente encapsulados por tejido conjuntivo, que tiene la función de contener la infección, aislando e impidiendo la diseminación de las micobacterias y delimitando la lesión del tejido sano. El objetivo de este e… Leer más



July 13rd, 2021

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Eliazar Camino Gutiérrez

Strategies for the prevention and control of Theileria equi and Babesia caballi in the equine population of Spain

Eliazar Camino Gutiérrez defended the PhD Thesis at the Faculty of Veterinary Medicine of the Complutense University of Madrid


Equine piroplasmosis (EP) is a parasitic disease of equids (horses, donkeys, mules and zebras) caused by two intraerythrocytic protozoan parasites within the phylum Apicomplexa: Theileria equi (previously named Babesia equi) and Babesia caballi. These parasites are mainly trasmitted by ixodid tick species belonging to several genera such as Dermacentor, Hyalomma and Rhipicephalus; however, transmission may also occur vertically in utero and iatrogenically. This disease has a hyperacute, acute, subacute or chronic form; affected animals often show variable and nonspecific clinical signs such as… Leer más



June 24th, 2021

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Laura Montecino Fernández

Detección y estudio genómico de genes asociados a la resistencia a colistina

Laura Montecino Fernández defended this presentation at the Faculty of Veterinary Medicine of the Complutense University of Madrid in order to obtain the Master of Research


La colistina es un antimicrobiano dosis-dependiente catiónico perteneciente a la familia de las polimixinas, cuya diana es la membrana externa de las bacterias Gram negativas, en concreto el lipopolisacárido (LPS), con el objetivo de aumentar la permeabilidad de la membrana provocando la fuga del contenido citoplasmático y la muerte de la bacteria. Debido sus efectos adversos, su uso se limitó y quedó prácticamente obsoleto en medicina humana, mientras que en medicina veterinaria se ha utilizado ampliamente durante décadas enfermedades infecciosas causadas por enterobacterias. Hace unos años s… Leer más



May 24th, 2021

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Andrea Ros Carrasco

Validation of real-time PCRs for the detection of mycobacteria causing animal tuberculosis

Andrea Ros Carrasco defended this Degree Final Project


Nowadays, animal tuberculosis is a major issue in many countries of the European Union. Although post-mortem detection of this disease is usually performed by microbiological culture, other methods to detect members of the Mycobacterium tuberculosis complex (MTBC) directly from tissue samples are being developed. One of the most developed and promising technique for this purpose is the polymerase chain reaction (PCR). This work focuses on the optimisation and validation of two Real-Time PCRs for the detection of M. caprae and M. bovis based on the lepA gene and a genomic deletion in the regio… Leer más



January 27th, 2021

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José Francisco Delgado Blas

Emergencia y diseminación de mecanismos de resistencia a antibióticos de último recurso en bacterias humanas, animales y ambientales

PhD Thesis defense by José Francisco Delgado Blas at the Faculty of Veterinary Medicine of the Complutense University of Madrid


El descubrimiento y desarrollo de los antibióticos revolucionó la medicina moderna, permitiendo el tratamiento de infecciones bacterianas consideradas incurables. La resistencia a los antibióticos es un fenómeno natural, mediante el cual las bacterias son capaces de adaptarse y sobrevivir a la actividad de estos compuestos. Por ello, el uso masivo e indiscriminado de los antibióticos aceleró la emergencia de bacterias multirresistentes, constituyendo actualmente uno de los mayores problemas sanitarios a nivel mundial. Los antibióticos que todavía conservan una elevada efectividad frente a un a… Leer más



December 17th, 2020

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Pilar Pozo Piñol

Use of Epidemiological Analytic Tools and Molecular Characterization Techniques to Inform Bovine Tuberculosis Eradication Programs

PhD Thesis defense by Pilar Pozo Piñol at the VISAVET Centre of the Complutense University of Madrid


Bovine tuberculosis (bTB) is an infectious disease with a complex epidemiology at the human-animal-environment interface which, despite the application of extensive control measures, is still prevalent in livestock and wildlife in several regions of Spain. The disease, caused by Mycobacterium bovis (and to a lesser extent M. caprae), remains a concern due to its negative impact on animal health and welfare, together with the important consequences for production and animal trade that its presence imposes. Eradication programs of bTB in cattle in Spain are based on a combination of regular test… Leer más



December 11st, 2020

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Álvaro Roy Cordero

Evaluation of new vaccines against tuberculosis in goats and advances in their immunological diagnosis

PhD Thesis defense by Álvaro Roy Cordero at the VISAVET Centre of the Complutense University of Madrid


Tuberculosis in goats is a zoonotic mycobacteriosis, mainly caused by M. caprae and M. bovis, which leads to important economic losses for the goat producers and may represent a reservoir of tuberculosis for other domestic and wild animal species, as well as humans. At the European level, the active diagnosis of tuberculosis in goats is limited to goat herds coexisting or having epidemiological links with infected cattle or when raw milk and products made from raw milk are intended for human consumption (European Regulation EC 853/2004). However, specific eradication programs have been impleme… Leer más




Last PhD Thesis
Last Master Thesis
Last Degree Thesis
Scientific Disertations
Indicators
PhD Thesis
Total Last 60 mo. Last 12 mo.
1 ZTA 23 ZTA 6 MYC 2
2 SUAT 22 MYC 3 NED 1
3 MYC 13 NED 3 ZTA 1
4 ICM 11 SUAT 3 SEVISEQ 1
5 NED 7 SEVISEQ 1
  VISAVET 83 17 5

Master Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 17 ZTA 3 ZTA 1
2 ZTA 14 NED 2
3 MYC 10 MYC 1
4 NED 7
5 ICM 7
  VISAVET 58 7 1

Thesis archive