Last scientific dissertations
January 20th, 2023
Vía publiDB
New Methodologies for the Diagnosis of Bovine Tuberculosis
PhD Thesis defense by Víctor Lorente Leal at the VISAVET Centre of the Complutense University of Madrid
Bovine tuberculosis (bTB) is a serious infectious disease of bovids that is subjected to eradication programmes around the world due to its negative effect in animal health and production, as well as its zoonotic potential. Despite the great advances in the eradication of the disease, bTB is still an ongoing problem in certain regions of the EU and Spain. The main objective of this doctoral thesis was the development of novel diagnostic and characterisation tools that can contribute in enhancing the efficiency of the eradication efforts. This was achieved through the development of sensitive a…
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November 28th, 2022
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Determination of reference intervals of haematological, biochemical and oxidative stress parameters in horses residing in equestrian centers in central Spain
PhD Thesis defense by Aránzazu Buendía Andrés at the VISAVET Centre of the Complutense University of Madrid
Currently, one of the main areas of the equine sector in Spain is the use of the horse for pleasure and sports competition purposes at equestrian centres1. The equine veterinary clinician develops an essential role in the health surveillance of these horses and one of the most frequent tools is the completion of clinical analysis. For the correct interpretation of these analysis, reference intervals, defined by the range of values of an analyte from a population with a defined health status, are necessary.
To date, the equine population living in equestrian centres at central Spain did not…
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September 16th, 2022
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Modelo experimental para Streptococcus suis: evaluación comparativa de dos técnicas dirigidas a la determinación de la presencia del patógeno en tejidos
Degree Final Project defended by Andrea Brigidano Lopez
Streptococcus suis (S. suis) es uno de los patógenos más relevantes en sanidad animal a los que se enfrenta actualmente el sector porcino a nivel mundial. Además, tiene un carácter zoonótico de importancia para la salud pública. Sin embargo, las estrategias disponibles para su control son limitadas, especialmente en lo referido a la disponibilidad de vacunas comerciales, debido a la ausencia de inmunidad cruzada asociado a su gran variabilidad antigénica. Es por ello por lo que la utilización de modelos animales para el estudio de candidatos vacunales y el empleo de métodos diagnósticos sensib…
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September 15th, 2022
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Evaluación de la serología para el diagnóstico de la tuberculosis en cérvidos
Eva Barrio Calvo defended this Degree Final Project
Fundamento y objetivo: Los cérvidos son reservorios de la tuberculosis (TB) para el ganado doméstico. La vigilancia de TB en cérvidos se basa sobre todo en el examen de lesiones compatibles con tuberculosis (LCT), cultivo e intradermotuberculinización (IDTB), aunque estas pruebas tienen ciertas limitaciones. Además, el Reglamento Delegado (UE) 2020/688 no especifica la prueba diagnóstica requerida para el movimiento de cérvidos dentro de la Unión Europea. Para este fin, es necesario una prueba rápida y coste-efectiva, entre las que se encuentran las pruebas de detección de anticuerpos. El obje…
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July 22nd, 2022
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Hepatitis E in the pig production chain: from farm to fork
PhD Thesis defense by Alejandro Navarro Gómez at the VISAVET Centre of the Complutense University of Madrid
Hepatitis E (HE) is one of the main acute viral hepatitis worldwide, and can represent an important problem in Public Health. The virus responsible for this disease is the hepatitis E virus (HEV), belonging to the Hepeviridae family. To date, 8 different genotypes of HEV are known. The genotypes that affect humans are genotypes 1-4, although the possible zoonotic potential of genotypes 5, 7 and 8 has been described. In developed countries, the causes of HE in humans are genotype 3 and 4, generally associated with the consumption of contaminated and under cooked food. The main animal reservoir …
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July 21st, 2022
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Zoonosis in wild ruminants and wild boars in the Region of Madrid
Silvia Úbeda Jiménez defended this Degree Final Project
Los patógenos infecciosos presentes en la fauna silvestre han adquirido una importancia creciente en nuestra sociedad ya que tienen un impacto trascendente sobre la Salud Pública por su capacidad de transmitirse a los humanos, lo que se conoce como zoonosis, y por ello es necesario llevar una adecuada vigilancia y control de estas enfermedades. El objetivo de este estudio es determinar la prevalencia de diferentes patógenos zoonósicos de relevancia en rumiantes salvajes y jabalíes en la Comunidad de Madrid durante el año 2021, enmarcados en el sistema de Vigilancia de fauna silvestre de esta r…
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July 21st, 2022
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Evaluación del efecto de la administración parenteral de AINEs y glucocoticoides en las pruebas de diagnóstico oficial de tuberculosis bovina en un modelo experimental caprino
Carlos Velasco Reinaldos defended this Degree Final Project
El rendimiento de las pruebas de diagnóstico de la tuberculosis (TB) en los rumiantes domésticos se puede ver afectado por diferentes factores. El objetivo del presente estudio fue evaluar si la aplicación fraudulenta vía parenteral de ketoprofeno (antiinflamatorio no esteroideo o AINE) o de dexametasona (glucocorticoide) en el ganado puede provocar interferencias en la prueba de diagnóstico oficial, la intradermotuberculinización (IDTB).
El modelo animal experimental elegido para el estudio fue el caprino. Se seleccionaron aleatoriamente 90 animales de un rebaño de aptitud lechera con una pr…
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July 21st, 2022
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Histopathological and immunohistochemical study of premature senescence of cells in forensic cases of dogs starvation due to animal abuse
Degree Final Project defended by Esther Vázquez Fernández
Animal abuse is of mayor concern in today`s society, with an increasing number of reported cases. Violence towards animals is considered an additional factor of interpersonal violence, making essential to advance in the field of forensic veterinary pathology. Starvation, the involuntary loss of body mass, is one of the main causes of death in cases of animal abuse. Starvation is due to a catabolic state that induce atrophy in most organs. However, the mechanism beyond atrophy is not fully understood. The aim of this research is to retrospectively study a series of dog forensic cases diagnosed …
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July 6th, 2022
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Puesta a punto y optimización de PCR a tiempo real para Vibrio spp.
Degree Final Project defended by Andrea Marcos Baqueiro
Aquaculture is a growing sector whose aim is the production of aquatic organisms such as animals and plants. Currently, infectious diseases are a great challenge for this sector. Therefore, it is necessary not only to implement prophylactic measures, but also to have diagnostic methods to obtain reliable results in a short period of time and at low cost. Among the most relevant pathogens in health surveillance in aquaculture, some species such as Vibrio alginolyticus, Vibrio anguillarum and Vibrio harvey stand out for representing a serious problem when it comes to their detection and precise …
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July 5th, 2022
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Detection of bacteria of the genus Rickettsia in ticks and development of a high resolution melting technique
Degree Final Project defended by Gonzalo Pérez Serrano
Ricekttsioses are a group of emerging zoonotic pathologies caused by bacteria of the genus Rickettsia. These bacteria are Gram-negative, intracellular bacillococci, and the diseases they produce are transmitted to vertebrates by vectors such as ticks, mites, fleas and lice. Due to their highly conserved genome, there are limitations in the identification of the different species of rickettsiae. In this work, the molecular detection of bacteria of the genus Rickettsia in ticks has been carried out by performing conventional PCR and sequencing of the ompA and ompB genes, which is a laborious and…
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