Last scientific dissertations
September 19th, 2024
Vía publiDB
Diagnosis of leishmaniasis in wild murine fauna in Spain
Degree Final Project defended by Paloma Alonso Collado
Leishmaniasis is a zoonotic parasitic disease caused by protozoa of the genus Leishmania, which is primarily transmitted by dipteran vectors (phlebotomine sandflies). It is a disease that affects a large part of the countries worldwide, including Spain, where it is considered endemic.
The outbreaks that have occurred in the Community of Madrid since 2009 due to infected leporids have brought wild reservoirs into focus. The diagnosis of the disease canpor be made by direct observation of amastigotes in areas of active multiplication, immunological diagnosis or molecular diagnosis.
The aim…
Leer más
September 19th, 2024
Vía publiDB
Study of the Toscana virus in lagomorphs
Sara Martín-Gromaz Esteban defended this Degree Final Project
The Toscana Virus (TOSV) is an arbovirus of the genus Phlebovirus, which is transmitted by the bite of phlebotomine sandflies of the genus Phlebotomus and is currently considered an emerging zoonotic pathogen. This virus is known to cause meningitis in humans in endemic areas of the Mediterranean, especially during the summer months when there is increased phlebotomine sandfly activity. Recent studies suggest that some mammals, including lagomorphs, could act as reservoirs or potential amplifying hosts of the virus in certain regions.
In addition, co-infection with Leishmania, which is transm…
Leer más
September 19th, 2024
Vía publiDB
Detection of Leishmania in rabbit ticks (Oryctolagus cuniculus)
Degree Final Project defended by Mª Leticia del Barrio Montañés
The study focused on the detection of Leishmania infantum in ticks collected from wild rabbits (Oryctolagus cuniculus) in the Community of Madrid. Leishmaniasis is a zoonotic disease transmitted by sandflies, and its control is critical due to its global spread and the lack of a vaccine for humans. The primary reservoir is the dog, but the outbreak in Madrid (2009-2012) evidenced hares and rabbits as competent reservoirs, suggesting the need to explore this disease further, for example, by examining other potential common vectors in these wild rabbits, such as ticks.
The main objective was to…
Leer más
July 4th, 2024
Vía publiDB
Evaluation of alternative antigens to PPDs for the diagnosis of caprine tuberculosis
Alberto Corroto Martín defended this Degree Final Project
Improving the sensitivity (Se) and specificity (Sp) performance of official tuberculosis (TB) tests in goats is crucial as their limited performance leads to the existence of false positives and false negatives, with the associated economic, health and confidence implications. Therefore, great efforts have been devoted to the search and evaluation of new antigens that can replace classical PPDs, such as bovine PPD (PPDb) and avian PPD (PPDa), in order to improve the performance of official TB ante-mortem diagnostic tests.
This study focuses on evaluating two new antigens, DST-F and P22, as re…
Leer más
July 4th, 2024
Vía publiDB
Detection of Crimean-Congo hemorrhagic fever virus in ticks obtained from wild animals
Degree Final Project defended by Inés Higueras Fernández
The Crimean-Congo Hemorrhagic Fever (CCHF) is an infectious and zoonotic disease of viral etiology, transmitted by ticks of the genus Hyalomma. The increase in positive cases of in Spain since its first detection in 2010, along with the rising number of positive ticks detected, suggests the need for more thorough control over the actual circulation of this virus in the country. To date, various studies have been conducted focusing on detecting the circulation of CCHFV in regions of the national territory with a history of positive cases, omitting those areas where such precedents did not exist…
Leer más
July 4th, 2024
Vía publiDB
Estudio histopatológico e inmunohistoquímico en cerdos infectados por la cepa Pol/DP/OUT21 de peste porcina africana
Javier de Pablo Moreno defended this Degree Final Project
El virus de la peste porcina africana (PPA) induce una enfermedad letal tanto en cerdos domésticos como salvajes, provocando graves pérdidas económicas en la producción porcina. Las cepas que afectan actualmente a Europa pertenecen al genotipo II. Por tanto, es necesario realizar estudios patogénicos con diferentes cepas de PPA, debido a la variabilidad entre ellas. Se realizó un estudio anatomopatológico completo en 12 cerdos infectados por la cepa del virus de la PPA Pol16/DP/OUT21 con puntuaciones tanto macroscópicas como histológicas. El cuadro agudo-subagudo que indujo es compatible con l…
Leer más
June 17th, 2024
Vía publiDB
Evaluación de la resistencia antimicrobiana en Salmonella y Escherichia coli en alimentos en puestos de control fronterizo de España (2021-2023)
Elena Fernández Cabrera defended this presentation at the Faculty of Veterinary Medicine of the Complutense University of Madrid in order to obtain the Master of Research
Escherichia coli y Salmonella son dos microorganismos pertenecientes a la familia Enterobacteriaceae que forman parte de la microbiota intestinal comensal de la mayoría de mamíferos, aunque también existen cepas patógenas capaces de causar infecciones. Estas bacterias pueden presentar una gran diversidad de mecanismos de resistencia antimicrobiana, siendo la producción de betalactamasas de espectro extendido (BLEEs) y betalactamasas tipo AmpC los más comunes y, en menor medida, las carbapenemasas, que a su vez es el mecanismo más preocupante. Estas enzimas confieren resistencia a los betalactá…
Leer más
June 12nd, 2024
Vía publiDB
New perspectives in the study of mayor emerging diseases in cetaceans: advances in the understanding of Herpesviruses, Morbilliviruses and Brucella
PhD Thesis defense by Ignacio Vargas Castro at the VISAVET Centre of the Complutense University of Madrid
The importance of cetacean conservation in scientific research is increasingly prominent, giving rise to growing global concern due to the extinction threat faced by several cetacean species. The protection and preservation of these animals benefit the entire marine ecosystem, as they are considered umbrella species. Furthermore, their charisma and popularity make them flagship species, playing a significant role in raising awareness and promoting conservation among the general public. Additionally, they serve a crucial function as sentinels of ocean health.
On the other hand, the "One Heal…
Leer más
June 6th, 2024
Vía publiDB
Study of factors affecting the diagnostic performance of cellular and humoral-based techniques for caprine tuberculosis
PhD Thesis defense by Javier Ortega Martín at the VISAVET Centre of the Complutense University of Madrid
Caprine tuberculosis (TB) is a zoonotic mycobacteriosis caused by members of the Mycobacterium tuberculosis complex (MTBC), mainly M. caprae and M. bovis. Due to its health and economic impact, this disease is subject to surveillance and eradication programs. In Spain, certain regions have been established specific eradication programs for those caprine herds epidemiologically related to cattle herds. In addition, caprine TB eradication programs have been implemented in some Autonomous Communities, also included in a specific manual of the Ministry of Agriculture, Fisheries and Food of Spain i…
Leer más
May 22nd, 2024
Vía publiDB
Patología y causas de varamiento en tortugas marinas de la Comunidad Valenciana
PhD Thesis defense by José Luis Crespo Picazo at the VISAVET Centre of the Complutense University of Madrid
The aim of this thesis is to apply epidemiological surveillance as a fundamental tool to learn about the occurrence of diseases and causes of death in a population in a given area, to monitor them over time and to propase control or mitigation strategies in management plans. In the case of the Valencian Community, as in many other regions at national and international level, a complete study of the pathologies and causes of death of sea turtles has not yet been carried out. This thesis is an ordered, systematic and complete study of the sea turtles that appeared in the Valencian Community duri…
Leer más
