Investigación

Brote de rinoneumonitis equina 2021 en España

Herpesvirus equino tipo 1 (HVE-1)

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Assessing red deer hunting management in the Iberian Peninsula: the importance of longitudinal studies

Investigación publicada en PeerJ

Understanding the dynamics of a wildlife population in relation to hunting strategies is essential to achieve sustainable management. We used monitoring data over 25 years from two red deer (Cervus elaphus) populations with different management (with and without supplemental feeding) in South Central Spain to: (i) characterise the density dependence of population dynamics under contrasted management, and (ii) provide the basis for sustainable extraction by considering the theoretical maximum sustainable yield (MSYt) as the reference. The red deer population displayed a typical management react… Leer más

Leishmaniosis en el día mundial de las enfermedades tropicales desatendidas

30 de enero #worldNTDday

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African Swine Fever

Frontiers in veterinary science publica este artículo de investigación

The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest… Leer más

Emergencia y diseminación de mecanismos de resistencia a antibióticos de último recurso en bacterias humanas, animales y ambientales

Tesis Doctoral defendida por José Francisco Delgado Blas en la Facultad de Veterinaria de la Universidad Complutense de Madrid

El descubrimiento y desarrollo de los antibióticos revolucionó la medicina moderna, permitiendo el tratamiento de infecciones bacterianas consideradas incurables. La resistencia a los antibióticos es un fenómeno natural, mediante el cual las bacterias son capaces de adaptarse y sobrevivir a la actividad de estos compuestos. Por ello, el uso masivo e indiscriminado de los antibióticos aceleró la emergencia de bacterias multirresistentes, constituyendo actualmente uno de los mayores problemas sanitarios a nivel mundial. Los antibióticos que todavía conservan una elevada efectividad frente a un a… Leer más

Use of Network Analysis and Spread Models to Target Control Actions for Bovine Tuberculosis in a State from Brazil

Artículo de investigación publicado en Microorganisms

Livestock movements create complex dynamic interactions among premises that can be represented, interpreted, and used for epidemiological purposes. These movements are a very important part of the production chain but may also contribute to the spread of infectious diseases through the transfer of infected animals over large distances. Social network analysis (SNA) can be used to characterize cattle trade patterns and to identify highly connected premises that may act as hubs in the movement network, which could be subjected to targeted control measures in order to reduce the transmission of c… Leer más

Non-Invasive Method to Detect Infection with Mycobacterium tuberculosis Complex in Wild Boar by Measurement of Volatile Organic Compounds Obtained from Feces with an Electronic Nose System

Sensors publica este artículo de investigación

More effective methods to detect bovine tuberculosis, caused by Mycobacterium bovis, in wildlife, is of paramount importance for preventing disease spread to other wild animals, livestock, and human beings. In this study, we analyzed the volatile organic compounds emitted by fecal samples collected from free-ranging wild boar captured in Doñana National Park, Spain, with an electronic nose system based on organically-functionalized gold nanoparticles. The animals were separated by the age group for performing the analysis. Adult (>24 months) and sub-adult (12–24 months) animals were anestheti… Leer más

Uso de herramientas de análisis epidemiológico y técnicas de caracterización molecular para guiar los programas de erradicación de la tuberculosis bovina

Tesis Doctoral defendida por Pilar Pozo Piñol en el Centro VISAVET de la Universidad Computense de Madrid

La tuberculosis bovina (TBb) es una enfermedad zoonósica de gran relevancia en la interfaz ser humano-animal-medio ambiente causada por las especies bacterianas Mycobacterium bovis y -en menor medida- M. caprae. La TBb tiene un gran impacto en la salud y bienestar animal, además de las graves consecuencias económicas que su presencia provoca en la producción y el comercio de ganado. A pesar de la aplicación de exhaustivas medidas de control, la prevalencia de la TBb es elevada en ganado y especies salvajes en varias regiones de España. Los programas de erradicación se basan en la aplicación ru… Leer más

- Los factores que lastran el control de la tuberculosis bovina en España - animalshealth.es/

Distinct African Swine Fever Virus Shedding in Wild Boar Infected with Virulent and Attenuated Isolates

Vaccine publica este artículo de investigación

Abstract: Since the reappearance of African swine fever virus (ASFV), the disease has spread in an unprecedented animal pandemic in Eurasia. ASF currently constitutes the greatest global problem for the swine industry. The wild boar (Sus scrofa) in which the pathogen has established wild self-sustaining cycles, is a key reservoir for ASFV, signifying that there is an urgent need to develop an effective vaccine against this virus. Current scientific debate addresses whether live attenuated vaccines (LAVs), which have shown promising results in cross-protection of susceptible hosts, may be feasi… Leer más

Primary and promiscuous functions coexist during evolutionary innovation through whole protein domain acquisitions

Investigación publicada en eLife

Abstract Molecular examples of evolutionary innovation are scarce and generally involve point mutations. Innovation can occur through larger rearrangements, but here experimental data is extremely limited. Integron integrases innovated from double-strand- toward single-strand-DNA recombination through the acquisition of the I2 a-helix. To investigate how this transition was possible, we have evolved integrase IntI1 to what should correspond to an early innovation state by selecting for its ancestral activity. Using synonymous alleles to enlarge sequence space exploration, we have retrieved 13… Leer más