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Últimas noticias de Investigación

1 de enero de 2018

Vía publiDB


The relevance of host overcrowding in wildlife epidemiology: A new spatially explicit aggregation index

Ecological Indicators publica este artículo de investigación


Species distribution and population abundance are keystone patterns in ecology, and currently also in epidemiology. The aggregation of individuals in the population is closely related to distribution and abundance, but they are not totally equivalent patterns. Despite the great efforts made in recent decades to harmonise the sampling protocols used to collect distribution and abundance data, studies regarding the development and testing of aggregation indices are scarce, even when individuals’ aggregation is quite relevant and necessary for the design of effective wildlife management policies.… Leer más



1 de enero de 2018

Vía publiDB


Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation

Biotechnology and bioengineering publica este artículo de investigación


Synthetic DNA design needs to harness the many information layers embedded in a DNA string. We previously developed the Evolutionary Landscape Painter (ELP), an algorithm that exploits the degeneracy of the code to increase protein evolvability. Here, we have used ELP to recode the integron integrase gene (intI1) in two alternative alleles. Although synonymous, both alleles yielded less IntI1 protein and were less active in recombination assays than intI1. We spliced the three alleles and mapped the activity decrease to the beginning of alternative sequences. Mfold predicted the presence of mo… Leer más



16 de diciembre de 2017

Vía publiDB


BMC Veterinary Research

Genetic diversity assessment of Tunisian Mycobacterium bovis population isolated from cattle

BMC Veterinary Research publica este artículo de investigación


Background The genetic diversity of M. bovis in Tunisia is still underestimated despite the implementation of an eradication program. The lack of data about spatial distribution of the M. bovis population hinders the control of bovine tuberculosis (bTB) progress. This study represents the largest molecular analysis of M. bovis isolates in Tunisia. It is aimed to upgrade the understanding of bTB epidemiology and the geographical distribution of the infection. Tuberculosis research was performed in cattle (n = 149) with TB-compatible lesions collected over 5 months from a slaughterh… Leer más



1 de diciembre de 2017

Servicio de Informática y Comunicación


Prevenir y reducir la transmisión de resistencia a los antimicrobianos

El Proyecto "HECTOR" reúne a grupos de investigación de Alemania, Países Bajos, España y el Reino Unido

Los antibióticos han revolucionado la medicina humana y veterinaria y han salvado innumerables vidas. Su descubrimiento representó un salto cuántico en el tratamiento de enfermedades infecciosas. Sin embargo, desafortunadamente, el aumento constante de bacterias resistentes a múltiples antimicrobianos han puesto en peligro su eficacia, en la medida en que las cepas resistentes se han convertido en una importante amenaza para la salud pública. Además, existe una creciente preocupación de que algunas infecciones bacterianas puedan volverse intratables en el futuro. Múltiples factores han contribuido a la situación actual. Uno de estos factores, ejemplificado por la reciente aparición y diseminación global de la resistencia a colistina o de β-lactamasas de espectro extendido (BLEE), es la presencia de determinantes de resistencia en elementos genéticos móviles, como plásmidos y transposones, que se transmiten rápidamente entre las mismas y diferentes especies bacterianas.… Leer más



1 de diciembre de 2017

Vía publiDB


Emerging Infectious Diseases

Characterization of Streptococcus pyogenes from Animal Clinical Specimens, Spain

Investigación publicada en Emerging Infectious Diseases


Streptococcus pyogenes appears to be almost exclusively restricted to humans, with few reports on isolation from animals. We provide a detailed characterization (emm typing, pulsed-field gel electrophoresis [PFGE], and multilocus sequence typing [MLST]) of 15 S. pyogenes isolates from animals associated with different clinical backgrounds. We also investigated erythromycin resistance mechanisms and phenotypes and virulence genes. We observed 2 emm types: emm12 (11 isolates) and emm77 (4 isolates). Similarly, we observed 2 genetic linages, sequence type (ST) 26 and ST63. Most isolates exhibited… Leer más



1 de diciembre de 2017

Vía publiDB


Journal of Clinical Microbiology

Multi-Laboratory Evaluation of a Novel Lateral Flow Immunochromatographic Assay for Confirming Isolation of Mycobacterium bovis from Veterinary Diagnostic Specimens

Journal of Clinical Microbiology publica este artículo de investigación


A novel lateral flow immunochromatographic device (LFD) was evaluated in several veterinary diagnostic laboratories. It was confirmed to be specific for Mycobacterium bovis and M. caprae cells. The performance of the novel LFD was assessed relative to the confirmatory tests routinely applied after culture (spoligotyping or qPCR) in each laboratory; liquid (MGIT or BacT/Alert) and/or solid (Stonebrink, Coletsos or Lowenstein-Jensen) cultures were tested. In comparison to spoligotyping of acid-fast positive MGIT cultures, percentage agreement between positive LFD and spoligotyping results was ex… Leer más



1 de diciembre de 2017

Vía publiDB


Research in Veterinary Science

Differentiation of Flavobacterium psychrophilum from Flavobacterium psychrophilum-like species by MALDI-TOF mass spectrometry

Investigación publicada en Research in Veterinary Science


Rainbow trout fry syndrome (RTFS) is an important infectious disease caused by Flavobacterium psychrophilum affecting farmed salmonids worldwide. Other Flavobacterium psychrophilum-like species (F. plurextorum, F. oncorhynchi, F. tructae, F. collinsii and F. piscis) have been isolated from diseased rainbow trout fry suspected of RTFS although the epidemiological and clinical relevance of these pathogens are unknown. The objective of this study was to evaluate the potential use of MALDI-TOF (Matrix-Assisted Laser Desorption/Ionization-Time of Flight) Mass Spectrometry as method for specific ide… Leer más



15 de noviembre de 2017

Vía publiDB


Frontiers in Microbiology

Genome comparison of erythromycin resistant Campylobacter from turkey identifies hosts and pathways for horizontal spread of erm(B) genes

Artículo de investigación publicado en Frontiers in Microbiology


Pathogens in the genus Campylobacter are the most common cause of food-borne bacterial gastro-enteritis. Campylobacteriosis, caused principally by Campylobacter jejuni and C. coli, is transmitted to humans by food of animal origin, especially poultry. As for many pathogens, antimicrobial resistance in Campylobacter is increasing at an alarming rate. Erythromycin prescription is the treatment of choice for clinical cases requiring antimicrobial therapy but this is compromised by mobility of the erythromycin resistance gene erm(B) between strains. Here we evaluate resistance to six antimicrobial… Leer más



10 de noviembre de 2017

Vía publiDB


Journal of Fish Diseases

First analysis by MALDI-TOF MS technique of Chryseobacterium species relevant

Journal of Fish Diseases publica este artículo de investigación



6 de noviembre de 2017

Vía publiDB


Diego Flórez Cuadrado

Caracterización genómica y resistencia a antimicrobianos de Campylobacter

Tesis Doctoral defendida por Diego Flórez Cuadrado en la Facultad de Veterinaria de la Universidad Complutense de Madrid


Las bacterias del género Campylobacter son las principales causantes de gastroenteritis de origen alimentario en todo el mundo, principalmente las especies Campylobacter jejuni y Campylobacter coli. Estos microorganismos colonizan el tracto digestivo de aves y mamíferos, siendo la principal vía de infección para las personas el consumo de carne de pollo contaminada. La infección producida por Campylobacter suele ser auto-limitante, pero ocasionalmente se producen complicaciones que requieren de tratamiento antimicrobiano, frecuentemente con eritromicina. La resistencia a eritromicina en Ca… Leer más







Próximamente en Investigación
Publicaciones Científicas
Últimas publicadas
Últimas líneas de investigación
Science Publication
Indicators
ISI Scientific Publications
Total Last 60 mo. Last 12 mo.
1 ICM 186 ZTA 76 SUAT 14
2 ZTA 179 SUAT 74 MYC 13
3 MYC 159 MYC 64 ZTA 11
4 SUAT 146 ICM 42 ICM 11
5 NED 65 NED 13 NED 2
  VISAVET 731 279 54

Impact Factor Average
Total Last 60 mo. Last 12 mo.
1 ZTA 3.45 ZTA 3.519 ZTA 3.769
2 MYC 2.6 ICM 2.488 ICM 2.75
3 SUAT 2.449 SUAT 2.46 SUAT 2.489
4 ICM 2.285 SEVISEQ 2.251 SEVISEQ 2.442
5 SEVISEQ 2.251 SAP 2.236 MYC 2.276
VISAVET 2.617 2.643 2.762

ISI Scientific Publications
Total Last 60 mo.
1 Vet. Microbiol. 59 Transbound. Emerg. Dis. 24
2 J. Clin. Microbiol. 38 Vet. Microbiol. 22
3 Transbound. Emerg. Dis. 35 Res. Vet. Sci. 21
4 Int. J. Syst. Evol. Microbiol. 31 PLoS ONE 17
5 Res. Vet. Sci. 30 BMC Vet. Res 15
  All journals 207   All journals 34

PhD Thesis
Total Last 60 mo. Last 12 mo.
1 ZTA 20 ZTA 9 ZTA 4
2 SUAT 20 SUAT 8 NED 1
3 ICM 11 ICM 3 SUAT 1
4 MYC 10 MYC 2
5 NED 5 NED 2
  VISAVET 71 25 6

Master Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 17 ZTA 5 ZTA 1
2 ZTA 13 MYC 3
3 MYC 9 NED 2
4 ICM 7 SAP 1
5 NED 6 ICM 1
  VISAVET 54 12 1