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28 de febrero de 2023

Vía publiDB


Transboundary and Emerging Diseases

A Maximum Entropy Species Distribution Model to Estimate the Distribution of Bushpigs on Madagascar and Its Implications for African Swine Fever

Investigación publicada en Transboundary and Emerging Diseases


Bushpigs (Potamochoerus larvatus) play a major role in the socio-ecosystem of Madagascar, particularly in rural areas. They are largely hunted by rural populations as a major source of income and protein. They can also represent a potential source of pathogens for domestic animals and people. For example, it is hypothesized that bushpigs might compromise African swine fever (ASF) eradication programs by sporadically transmitting the virus to domestic pigs. However, available knowledge on the distribution of bushpigs in Madagascar is limited. In this study, we estimated the distribution of bush… Leer más



28 de febrero de 2023

Vía publiDB


Zoonoses and Public Health

Mycobacterium bovis in Egyptian mongoose, Spain

Zoonoses and Public Health publica este artículo de investigación


Tuberculosis caused by Mycobacterium bovis and other related mycobacteria has been reported in a wide range of mammals worldwide. In the case of the Herpestidae family, Mycobacterium mungi and M. bovis, both belonging to the Mycobacterium tuberculosis Complex, have been reported in banded mongooses (Mungos mungo) in Africa and in Egyptian mongooses (Herpestes ichneumon) in Portugal, respectively. Thus, we hypothesized that Tuberculosis may occur in Egyptian mongooses from Spain. Twenty-five found dead Egyptian mongooses were necropsied in order to detect macroscopic TB-compatible lesions and m… Leer más



22 de febrero de 2023

Vía publiDB


Transboundary and Emerging Diseases

Development of an Effective Oral Vaccine Dissemination Strategy against Classical Swine Fever for Wild Boar in Gifu Prefecture, Japan

Artículo de investigación publicado en Transboundary and Emerging Diseases


In September 2018, classical swine fever (CSF) reemerged in Japan after more than a quarter of a century. After the first notification on a pig farm, wild boars positive for CSF were found continuously in the surrounding area. Gifu was the first prefecture in Japan to disseminate oral vaccines to wild boars in March 2019, with vaccines spread to approximately 14,000 sites between 2019 and 2020. While these diligent measures seemed to have shown some effectiveness, several vaccine spray sites remained without wild boar emergence. Based on the vaccine dissemination records from these periods, th… Leer más



21 de febrero de 2023

Vía publiDB


Transboundary and Emerging Diseases

Accuracy of Tests for Diagnosis of Animal Tuberculosis: Moving Away from the Golden Calf (and towards Bayesian Models)

Investigación publicada en Transboundary and Emerging Diseases


Te last decades have seen major eforts to develop new and improved tools to maximize our ability to detect tuberculosis-infected animals and advance towards the objective of disease control and ultimately eradication. Nevertheless, there is still uncertainty regarding test performance due to the wide range of specifcity and especially sensitivity estimates published in the scientifc literature. Here, we performed a systematic review of the literature on studies that evaluated the performance of tuberculosis diagnostic tests used in animals through Bayesian Latent Class Models (BLCMs), which do… Leer más



20 de febrero de 2023

Vía publiDB


Scientific reports

A tool to enhance antimicrobial stewardship using similarity networks to identify antimicrobial resistance patterns across farms

Scientific reports publica este artículo de investigación


Antimicrobial resistance (AMR) is one of the major challenges of the century and should be addressed with a One Health approach. This study aimed to develop a tool that can provide a better understanding of AMR patterns and improve management practices in swine production systems to reduce its spread between farms. We generated similarity networks based on the phenotypic AMR pattern for each farm with information on important bacterial pathogens for swine farming based on the Euclidean distance. We included seven pathogens: Actinobacillus suis, Bordetella bronchiseptica, Escherichia coli, Glae… Leer más



20 de febrero de 2023

Vía publiDB


Scientific reports

Differences in skin test reactions to official and defined antigens in guinea pigs exposed to non-tuberculous and tuberculous bacteria

Artículo de investigación publicado en Scientific reports


The single and comparative intradermal tuberculin tests (SITT and CITT) are official in vivo tests for bovine tuberculosis (TB) diagnosis using bovine and avian purified protein derivatives (PPD-B and PPD-A). Infection with bacteria other than Mycobacterium tuberculosis complex (MTC) can result in nonspecific reactions to these tests. We evaluated the performance of the skin test with PPDs and new defined antigens in the guinea pig model. A standard dose (SD) of Rhodococcus equi, Nocardia sp., M. nonchromogenicum, M. monacense, M. intracellulare, M. avium subsp. paratuberculosis, M. avium subs… Leer más



14 de febrero de 2023

Vía publiDB


Portable Differential Detection of CTX-M ESBL Gene Variants, blaCTX-M-1 and blaCTX-M-15, from Escherichia coli Isolates and Animal Fecal Samples Using Loop-Primer Endonuclease Cleavage Loop-Mediated Isothermal Amplification

Microbiology Spectrum publica este artículo de investigación


Cefotaximase-Munich (CTX-M) extended-spectrum beta-lactamase (ESBL) enzymes produced by Enterobacteriaceae confer resistance to clinically relevant third-generation cephalosporins. CTX-M group 1 variants, CTX-M-1 and CTX-M-15, are the leading ESBL-producing Enterobacteriaceae associated with animal and human infection, respectively, and are an increasing antimicrobial resistance (AMR) global health concern. The blaCTX-M-1 and blaCTX-M-15 genes encoding these variants have an approximate nucleotide sequence similarity of 98.7%, making effective differential diagnostic monitoring difficult. Loop… Leer más



26 de enero de 2023

Vía publiDB


Aging cell

Treatment with the senolytics dasatinib/quercetin reduces SARS-CoV-2-related mortality in mice

Aging cell publica este artículo de investigación


The enormous societal impact of the ongoing COVID-19 pandemic has been particularly harsh for some social groups, such as the elderly. Recently, it has been suggested that senescent cells could play a central role in pathogenesis by exacerbating the pro-inflammatory immune response against SARS-CoV-2. Therefore, the selective clearance of senescent cells by senolytic drugs may be useful as a therapy to ameliorate the symptoms of COVID-19 in some cases. Using the established COVID-19 murine model K18-hACE2, we demonstrated that a combination of the senolytics dasatinib and quercetin (D/Q) signi… Leer más



25 de enero de 2023

Servicio de Informática y Comunicación


El grupo de investigación Vigilancia Sanitaria de la UCM supera su segunda evaluación externa con una calificación de excelente

La Agencia Estatal de Investigación otorga 96 de los 100 puntos posibles al grupo en el 30 aniversario de su creación

El grupo de investigación Vigilancia Sanitaria, adscrito al Centro VISAVET de la Universidad Complutense de Madrid (UCM), ha recibido una calificación de excelente en la segunda evaluación externa por parte de Agencia Estatal de Investigación (AEI) dependiente del Ministerio de Ciencia e Innovación.El grupo, dirigido por el profesor Lucas Domínguez Rodríguez, Catedrático de la UCM, está formado principalmente por investigadores docentes de la Facultad de Veterinaria de la UCM y cuenta entre sus integrantes participantes de otras instituciones como el Instituto de Salud Carlos III, el Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, el Instituto de Investigación en Recursos Cinegéticos, así como las Universidades de Burgos, Extremadura, Minnesota y Europea de Madrid.

UCM Health Surveillance Research Group 30 años dedicados a la vigilancia sanitaria Leer más



20 de enero de 2023

Vía publiDB


Víctor Lorente Leal

Nuevas metodologías para el diagnóstico de la tuberculosis bovina

Tesis Doctoral defendida por Víctor Lorente Leal en el Centro VISAVET de la Universidad Computense de Madrid


La tuberculosis bovina (TBb) es una enfermedad infecciosa grave de los bóvidos que está sujeta a programas de erradicación en todo el mundo debido a su efecto negativo en la salud y producción animal, así como ser una potencial zoonosis. A pesar de los grandes avances en la erradicación de la enfermedad, la TBb sigue siendo un problema persistente en determinadas regiones de la UE y España. El objetivo principal de esta tesis doctoral fue el desarrollo de nuevas herramientas de diagnóstico y caracterización que puedan contribuir a mejorar la eficiencia de los esfuerzos de erradicación. Esto se… Leer más







Próximamente en Investigación
Publicaciones Científicas
Últimas publicadas
Últimas líneas de investigación
Science Publication
Indicators
ISI Scientific Publications
Total Last 60 mo. Last 12 mo.
1 ZTA 241 SUAT 57 ICM 16
2 ICM 227 ZTA 56 MYC 12
3 MYC 214 MYC 55 SUAT 11
4 SUAT 202 ICM 40 SAP 9
5 NED 73 SAP 20 ZTA 6
  VISAVET 1054 313 62

Impact Factor Average
Total Last 60 mo. Last 12 mo.
1 SAP 5.985 SAP 6.933 SAP 10.827
2 ZTA 3.9 ZTA 5.165 NED 4.521
3 SUAT 2.937 ICM 4.237 ZTA 4.452
4 MYC 2.817 SUAT 4.136 SUAT 4.415
5 DICM 2.776 NED 3.764 ICM 4.319
VISAVET 3.238 4.616 5.665

ISI Scientific Publications
Total Last 60 mo.
1 Transbound Emerg Dis 90 Transbound Emerg Dis 39
2 Vet Microbiol 87 Front Vet Sci 38
3 Prev Vet Med 74 Prev Vet Med 18
4 PLoS ONE 55 PLoS ONE 16
5 Front Vet Sci 53 Res Vet Sci 14
  All journals 346   All journals 38

PhD Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 24 MYC 3 NED 1
2 ZTA 23 NED 3 SUAT 1
3 MYC 13 SUAT 3 SEVISEQ 1
4 ICM 11 ZTA 2
5 NED 8 SEVISEQ 2
  VISAVET 90 16 4

Master Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 17 MYC 1
2 ZTA 14 NED 1
3 MYC 10 ZTA 1
4 ICM 7
5 NED 7
  VISAVET 58 4 0