Investigación

Protective effect of heat-inactivated Mycobacterium bovis applied intramuscularly is associated with enhanced lung immune response in caprine tuberculosis

Investigación publicada en Veterinary Research

Caprine tuberculosis (TB) causes a zoonotic disease with significant economic and health implications. However, excluding some regions, goat herds are not subjected to official TB eradication programs. Implementing vaccination protocols for this species could provide a complementary and effective control strategy against TB. We assessed the protective efficacy and immune response associated with a heat-inactivated Mycobacterium bovis (M. bovis)-based immunostimulant (HIMB) applied intramuscularly against caprine pulmonary TB on 20 kid goats (10 immunized, 10 controls) naturally exposed to M. c… Leer más

Diving Into the Depths: Unveiling the Main Etiologies of Piscine Lactococcosis With a Novel Multiplex qPCR Assay

Investigación publicada en Journal of Fish Diseases

Piscine lactococcosis poses a significant threat to a wide range of cultured and wild fish populations worldwide, typically presenting as acute haemorrhagic septicemia with high morbidity and mortality. Although Lactococcus garvieae was historically considered the sole causative agent of piscine lactococcosis, recent studies have identified L. petauri and L. formosensis as additional, highly pathogenic species. In this study, we developed a novel TaqMan-based multiplex qPCR assay for the simultaneous detection and differentiation of L. garvieae, L. petauri and L. formosensis, following a pange… Leer más

Primary leptomeningeal histiocytic lymphoproliferative disorder associated with SARS-CoV-2 brain infection in k18-hACE2 mouse: a case report

Laboratory Animal Research publica este artículo de investigación

Background: Histiocytic proliferative disorders in the central nervous system are rare, and their potential association with viral infections remains largely unexplored. This case is relevant because it suggests a potential interaction between SARS-CoV-2 neuroinvasion and tumor development, providing insights into how viral infections might influence oncogenesis. Case presentation: A 4.5-month-old male k18-hACE-2 mouse, part of an experimental study of SARS-CoV-2, displayed a small mass in leptomeningeal area composed by neoplastic round cells. This process is associated with typical acute in… Leer más

Evidence of ESBL plasmid transfer and selective persistence of multiple host-associated Escherichia coli isolates in a chicken cecal fermentation model

Investigación publicada en Applied and Environmental Microbiology

The guts of animals and humans harbor diverse microbial communities that are regularly exposed to bacteria originating from food, water, and their surroundings. Species such as Escherichia coli are adept at colonizing multiple hosts, along with surviving in the environment. By encoding pathogenic traits and transmissible forms of antimicrobial resistance (AMR), E. coli can also pose a zoonotic risk. Our understanding of the factors that govern host residency is limited. Here, we used a chicken cecal fermentation model to study survival and the AMR transfer potential of 17 host-associated exten… Leer más

Persistent multispecies dissemination of armA-carrying IncR plasmids among clinical and environmental bacterial populations in a Spanish veterinary hospital

Artículo de investigación publicado en Journal of Clinical Microbiology

Aminoglycoside resistance mediated by 16S rRNA methyltransferases poses a growing threat in both human and veterinary medicine. Here, we conducted a retrospective genomic study of Enterobacterales isolates (n = 789) collected from clinical samples at a veterinary teaching hospital in Spain between 2011 and 2020. We identified four high-level aminoglycoside-resistant ST171 Enterobacter hormaechei subsp. xiangfangensis isolates carrying the armA gene, all from horses. Using Illumina and Nanopore sequencing, we determined that armA was located on a 70 kb IncR plasmid, also carrying other resistan… Leer más

Abattoir Surveillance: Identifying Risk Factors Associated with Bovine Tuberculosis Lesion Detection in a Low Prevalence Region

Preventive Veterinary Medicine publica este artículo de investigación

Abattoir surveillance is a key component in control and eradication programs against bovine tuberculosis (bTB). In low-prevalence or officially tuberculosis-free (OTF) regions in which active surveillance is typically limited or non-existent, postmortem inspection at the abattoir constitutes one of the main diagnostic tool to guarantee the absence of disease transmission. Here, we evaluated the performance of abattoir postmortem inspection in Galicia, a low-prevalence region in Spain (now OTF). Between 2014 and 2019, 1,784,261 animals were culled in 41 abattoirs, of which a small proportion (0… Leer más

Evolution of Suspected Cat Abuse Between 2020 and 2024 in the Community of Madrid (Spain)

Artículo de investigación publicado en Animals

Animal abuse is a serious and underreported problem, with cats, particularly those living in colonies, being frequent victims. In Spain, reliable data on feline abuse are limited. This study evaluated the cause, manner and mechanisms of death from 53 cats over five years at the Pathology and Forensic Veterinary Unit of the VISAVET Health Surveillance Center in Madrid (Spain). More than half of the cats died from non-natural causes, including blunt force trauma, poisoning, and projectile injuries, while the remaining cats died from natural causes. Compared to a previous regional study, suspect… Leer más

- La Complutense detecta una tendencia al alza en los casos de maltrato a gatos en Madrid - animalshealth.es

- Revelan un aumento de casos sospechosos de maltrato animal en colonias felinas en la Comunidad de Madrid - diarioveterinario.com

Evaluación de cepas del virus de la peste porcina Africana de baja a moderada virulencia: perspectivas de expertos e implicaciones para los planes de vigilancia

Trabajo presentado por Abdiel Chaparro Ríos para la obtención del Máster de Investigación en Ciencias Veterinarias

Néstor Porras, ACVP Editors Choice Award 2025

Su estudio de evaluación histopatológica en jabalíes infectados por el virus de la peste porcina africana, ha obtenido el premio en la categoria de estudio experimental

Nuestro compañero Néstor Porras González, investigador del Servicio de Patología Animal y Veterinaria Forense del centro Visavet y estudiante de doctorado de la Facultad de Veterinaria UCM, ha sido selecionado por los editores de Veterinary Pathology para recibir el Premio de los Editores de American College of Veterinary Pathology a un Estudio Experimental. Este premio ha reconocido en el artículo "Histopathologic evaluation system of African swine fever in wild boar infected with high (Arm07) and low (Lv17/WB/Riel) isolates" el diseño del estudio, la claridad, la presentación de los datos y el impacto potencial. El premio será entregado en la próxima Reunión Anual de la @americancollegevetpath ACVP en Nueva Orleans, Luisiana, EE. UU.… Leer más

Retrospective analysis of the clinical approach practiced in dog bite cases caused by Vipera latastei, Vipera seoanei and Vipera aspis

Artículo de investigación publicado en The Veterinary Journal

Snakebites pose a significant public health risk to both humans and animals in many countries. In Spain, the presence of three viper species, Vipera latastei, Vipera seoanei, and Vipera aspis, complicates clinical management in veterinary settings. There is currently no standardized veterinary protocol for treating viper bites in many countries. This retrospective study analyzed the clinical approaches employed by Spanish veterinary centers in treating canine viper bites within the distribution range of these species. Data from 62 clinical cases across 58 veterinary centers were reviewed, incl… Leer más