Líneas de Investigación
Líneas de investigación del Centro VISAVET
Proyectos de Investigación
Proyectos vigentes en convocatorias públicas
Redes de Investigación
Redes de investigación del Centro VISAVET
Publicaciones científicas Publicaciones científicas ISI del Centro VISAVET
Tesis
Tesis Doctorales y Disertaciones científicas
del Centro VISAVET
Premios de investigación
Tesis e investigadores premiados
Últimas noticias de Investigación
1 de junio de 2018
Vía publiDB
Human Pasteurella multocida Infection with Likely Zoonotic Transmission from a Pet Dog, Spain
Investigación publicada en Emerging Infectious Diseases
We report a case of urinary tract infection caused by an unusual genotype (sequence type 211) of Pasteurella multocida associated with human infection. Molecular genetic analysis of P. multocida isolates obtained from the human patient and his pet strongly suggests a zoonotic transmission of this bacterium…
Leer más
1 de junio de 2018
Vía publiDB
Impact of piglet oral vaccination against tuberculosis in endemic free-ranging wild boar populations
Investigación publicada en Preventive Veterinary Medicine
The Eurasian wild boar (Sus scrofa) is the main wild reservoir of the Mycobacterium tuberculosis complex in Mediterranean woodlands and a key risk factor for cattle tuberculosis (TB) breakdowns. Wild boar vaccination therefore has the potential to be a valuable tool for TB control. We tested two orally delivered vaccines, heat-inactivated Mycobacterium bovis (IV) and BCG, in four sites (two per vaccine type: one Managed and one Natural or unmanaged) during four years. TB was also monitored in 15 unvaccinated sites (spatial control), as well as in all sites from one year prior to intervention (…
Leer más
23 de mayo de 2018
Vía publiDB
Evaluation of the use of a needle-free injection syringe as a cause of non-specific reactions in the intradermal tuberculin test used for the diagnosis of bovine tuberculosis
Artículo de investigación publicado en Research in Veterinary Science
The objective of the study was to elucidate whether the use of the needle-free Dermojet syringe, which is based on a high pressure inoculation and is used to inject tuberculin in cattle in several countries, may, in itself, cause skin reactions that can be interpreted as positive reactions to the intradermal tests that are not, in fact, related to the real infection status of the animals.
Forty-four cattle from an officially tuberculosis-free (OTF) herd were selected, and four single intradermal tuberculin (SIT) tests were performed on each animal, two on each side of the neck. Three differen…
Leer más
17 de mayo de 2018
Vía publiDB
Temporal analysis of the interference caused by paratuberculosis vaccination on the tuberculosis diagnostic tests in goats
Artículo de investigación publicado en Preventive Veterinary Medicine
Vaccination against paratuberculosis (PTB) in goats is a cost-effective control strategy, and is also effective as regards preventing the onset of clinical cases. However, it causes interference in the diagnostic tests used in the control of tuberculosis (TB). A group of 99 goats from a herd with no history of TB or PTB infection was vaccinated against PTB at seven months of age. They then underwent consecutive intradermal tests [single (SIT) and comparative (CIT) intradermal tuberculin tests), interferon-gamma release assays (IGRA) and two serological tests (p22_CE and DR-ELISA) every three m…
Leer más
2 de mayo de 2018
Vía publiDB
Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance
Journal of visualized experiments : JoVE publica este artículo de investigación
Multicopy plasmids are extremely abundant in prokaryotes but their role in bacterial evolution remains poorly understood. We recently showed that the increase in gene copy number per cell provided by multicopy plasmids could accelerate the evolution of plasmid-encoded genes. In this work, we present an experimental system to test the ability of multicopy plasmids to promote gene evolution. Using simple molecular biology methods, we constructed a model system where an antibiotic resistance gene can be inserted into Escherichia coli MG1655, either in the chromosome or on a multicopy plasmid. We …
Leer más
1 de mayo de 2018
Vía publiDB
The use of serological tests in combination with the intradermal tuberculin test maximizes the detection of tuberculosis infected goats
Veterinary Immunology and Immunopathology publica este artículo de investigación
The diagnosis of tuberculosis (TB) in goats is based mainly on the single and comparative intradermal tuberculin (SIT and CIT) tests and, exceptionally, on the interferon-gamma (IFN-γ) assay, however they are not perfect in terms of sensitivity and specificity. Nevertheless, various serological assays that provide a potential cost-effective approach for the control of TB are also available or under development, and a variety of results have been reported regarding the ability of these tests to detect infected animals, particularly in the early stages of infection.
In the present study, S…
Leer más
1 de mayo de 2018
Vía publiDB
Streptococcus penaeicida sp. nov., isolated from a diseased farmed Pacific white shrimp (Penaeus vannamei)
Investigación publicada en International Journal of Systematic and Evolutionary Microbiology
Strain CAIM 1838T, isolated from the hepatopancreas of a cultured diseased Pacific white shrimp (Penaeusvannamei), was subjected to characterization by a polyphasic taxonomic approach. On the basis of 16S rRNA gene sequence analysis, strain CAIM 1838T was most closely related to Streptococcus bovimastitidis 99.3 % and to other species of the Pyogenes clade of Streptococcus with lower similarity values. Average nucleotide identity values and the genome-to-genome distance of strain CAIM 1838T, as compared with the type strains, confirmed the separate species status with closely related spe…
Leer más
1 de mayo de 2018
Vía publiDB
Gaps in African swine fever: Analysis and priorities
Investigación publicada en Transboundary and Emerging Diseases
African swine fever (ASF) causes greater sanitary, social and economic impacts on swine herds than many other swine diseases. Although ASF was first described in 1921 and it has affected more than fifty countries in Africa, Europe and South America, several key issues about its pathogenesis, immune evasion and epidemiology remain uncertain. This article reviews the main characteristics of the causative virus, its molecular epidemiology, natural hosts, clinical features, epidemiology and control worldwide. It also identifies and prioritizes gaps in ASF from a horizontal point of view encompassi…
Leer más
20 de abril de 2018
Servicio de Informática y Comunicación
Bruno González-Zorn, premio PRAN 2017
El investigador de la Universidad Complutense de Madrid obtiene el premio en la categoría de mejor publicación científica sobre resistencia a los antibióticos
La Agencia Española de Medicamentos y Productos Sanitarios (AEMPS), dependiente del Ministerio de Sanidad, Servicios Sociales e Igualdad, ha anunciado la concesión de los Premios “Plan Nacional de Resistencia a los Antibióticos” (PRAN) 2017 a cinco proyectos desarrollados en el ámbito de la lucha frente al problema de la resistencia a los antimicrobianos.… Leer más
9 de abril de 2018
Vía publiDB
Ovine Mannheimia haemolytica isolates from lungs with and without pneumonic lesions belong to similar genotypes
Artículo de investigación publicado en Veterinary Microbiology
This study investigated the genetic characteristics of 121 ovine Mannheimia haemolytica isolates from lungs with (n = 75) and without pneumonic lesions (n = 46) using multilocus sequence typing (MLST), virulence-associated gene typing and pulsed-field gel electrophoresis (PFGE). Twelve STs were identified with most isolates (81%) belonged to ST16, ST28 and ST8. Analysis of the M. haemolytica MLST Database indicate a wide distribution of these genotypes in small ruminants, never reported in bovine isolates. This could suggest the adaptation of certain genetic lineages of…
Leer más
