Inicio \ Investigación




Últimas noticias de Investigación

25 de enero de 2023

Servicio de Informática y Comunicación


El grupo de investigación Vigilancia Sanitaria de la UCM supera su segunda evaluación externa con una calificación de excelente

La Agencia Estatal de Investigación otorga 96 de los 100 puntos posibles al grupo en el 30 aniversario de su creación

El grupo de investigación Vigilancia Sanitaria, adscrito al Centro VISAVET de la Universidad Complutense de Madrid (UCM), ha recibido una calificación de excelente en la segunda evaluación externa por parte de Agencia Estatal de Investigación (AEI) dependiente del Ministerio de Ciencia e Innovación.El grupo, dirigido por el profesor Lucas Domínguez Rodríguez, Catedrático de la UCM, está formado principalmente por investigadores docentes de la Facultad de Veterinaria de la UCM y cuenta entre sus integrantes participantes de otras instituciones como el Instituto de Salud Carlos III, el Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria, el Instituto de Investigación en Recursos Cinegéticos, así como las Universidades de Burgos, Extremadura, Minnesota y Europea de Madrid.

UCM Health Surveillance Research Group 30 años dedicados a la vigilancia sanitaria Leer más



20 de enero de 2023

Vía publiDB


Víctor Lorente Leal

Nuevas metodologías para el diagnóstico de la tuberculosis bovina

Tesis Doctoral defendida por Víctor Lorente Leal en el Centro VISAVET de la Universidad Computense de Madrid


La tuberculosis bovina (TBb) es una enfermedad infecciosa grave de los bóvidos que está sujeta a programas de erradicación en todo el mundo debido a su efecto negativo en la salud y producción animal, así como ser una potencial zoonosis. A pesar de los grandes avances en la erradicación de la enfermedad, la TBb sigue siendo un problema persistente en determinadas regiones de la UE y España. El objetivo principal de esta tesis doctoral fue el desarrollo de nuevas herramientas de diagnóstico y caracterización que puedan contribuir a mejorar la eficiencia de los esfuerzos de erradicación. Esto se… Leer más



19 de enero de 2023

Vía publiDB


Nature Biotechnology

Engineered live bacteria suppress Pseudomonas aeruginosa infection in mouse lung and dissolve endotracheal-tube biofilms

Investigación publicada en Nature Biotechnology


Engineered live bacteria could provide a new modality for treating lung infections, a major cause of mortality worldwide. In the present study, we engineered a genome-reduced human lung bacterium, Mycoplasma pneumoniae, to treat ventilator-associated pneumonia, a disease with high hospital mortality when associated with Pseudomonas aeruginosa biofilms. After validating the biosafety of an attenuated M. pneumoniae chassis in mice, we introduced four transgenes into the chromosome by transposition to implement bactericidal and biofilm degradation activities. We show that this engineered strain h… Leer más



17 de enero de 2023

Vía publiDB


Animals

Characterization of the Fecal and Mucosa-Associated Microbiota in Dogs with Chronic Inflammatory Enteropathy

Investigación publicada en Animals


Chronic inflammatory enteropathies are the most common cause of chronic vomiting and diarrhea in dogs. The pathogenesis of this disease is known to be multifactorial, where intestinal barrier dysfunction, immunological dysregulation and gut microbiota changes play a central role. Most sequencing studies assessing the intestinal microbiota in canine species have been made to evaluate fecal samples. Therefore, in this study, we aimed to characterize the intestinal bacterial microbiota from duodenal biopsies and fecal samples in dogs with inflammatory bowel disease at the diagnosis time and to co… Leer más



8 de enero de 2023

Vía publiDB


Struggling to improve farm biosecurity: Do free advice and subsidies hit the target?

Preventive Veterinary Medicine publica este artículo de investigación


Biosafety measures (BSMs) often aim at reducing the likelihood of cross-species interactions at the wildlife-livestock interface. Examples include means to segregate wild ungulates from cattle at waterholes or at feeders. Subsidies or incentives for BSM implementation are expected to contribute to improved BSM acceptance. However, several recent experiences led us to write a cautionary commentary on the variable success of incentives in farm biosafety promotion. We list examples where, after offering farm-specific biosecurity action plans for free or subsidizing 100% of the cost of a given BSM… Leer más



4 de enero de 2023

Vía publiDB


What about the bull? A systematic review about the role of males in bovine infectious infertility within cattle herds

Artículo de investigación publicado en Veterinary and Animal Science


Numerous pathogens affect cow fertility. Nevertheless, little information has been published about microorganisms associated with cattle infertility focusing on bulls. The present review offers a current analysis and highlights potential key aspects on the relevance of bulls in the emergence of infertility problems of infectious origin within herds that are still not completely determined. The present systematic review was conducted using the PubMed, Web of Science, and Scopus databases on December 9, 2022. In total, 2,224 bibliographic records were reviewed and, according to strict inclusion … Leer más



24 de diciembre de 2022

Vía publiDB


Animals

Molecular Epidemiology of Pasteurella multocida Associated with Bovine Respiratory Disease Outbreaks

Animals publica este artículo de investigación


Studies that characterize bovine respiratory disease (BRD)-associated Pasteurella multocida isolates are scarce compared with research on isolates from other hosts and clinical backgrounds. In the present study, 170 P. multocida isolates from 125 BRD outbreaks were characterized by capsular and LPS typing as well as by virulotyping. Three capsular types (A, B, F) and three LPS genotypes (L2, L3, L6) were identified. Capsular and LPS typing revealed a very low genetic diversity (GD = 0.02) among P. multocida, with most isolates belonging to genotype A:L3 (97.6%). Virulotyping identified seven v… Leer más



22 de diciembre de 2022

Vía publiDB


Scientific reports

A proof-of-concept study to investigate the efficacy of heat-inactivated autovaccines in Mycobacterium caprae experimentally challenged goats

Artículo de investigación publicado en Scientific reports


This study aimed to assess the efficacy of a heat-inactivated Mycobacterium caprae (HIMC) vaccine in goats experimentally challenged with the same strain of M. caprae. Twenty-one goats were divided into three groups of seven: vaccinated with heat-inactivated Mycobacterium bovis (HIMB), with HIMC and unvaccinated. At 7 weeks post-vaccination all animals were endobronchially challenged with M. caprae. Blood samples were collected for immunological assays and clinical signs were recorded throughout the experiment. All goats were euthanized at 9 weeks post-challenge. Gross pathological examination… Leer más



21 de diciembre de 2022

Vía publiDB


mSphere

Genomics, Transcriptomics, and Metabolomics Reveal That Minimal Modifications in the Host Are Crucial for the Compensatory Evolution of ColE1-Like Plasmids

mSphere publica este artículo de investigación


Plasmid-mediated antimicrobial resistance is one of the major threats to public health worldwide. The mechanisms involved in the plasmid/host coadaptation are still poorly characterized, and their understanding is crucial to comprehend the genesis and evolution of multidrug-resistant bacteria. With this purpose, we designed an experimental evolution using Haemophilus influenzae RdKW20 as the model strain carrying the ColE1-like plasmid pB1000. Five H. influenzae populations adapted previously to the culture conditions were transformed with pB1000 and subsequently evolved to compensate for the … Leer más



20 de diciembre de 2022

Vía publiDB


Science of the total environment

Environmental factors driving fine-scale ixodid tick abundance patterns

Investigación publicada en Science of the total environment


Tick abundance is an essential demographic parameter to infer tick-borne pathogen transmission risks. Spatiotemporal patterns of tick abundance are heterogeneous, so its determinants at small spatial scales need to be understood to reduce their negative effects on hosts. Current knowledge of these determinants is scarce, especially in Mediterranean environments, limiting the possibilities for designing efficient tick control strategies. With the goal of unravelling tick abundance determinants and informing new tick management strategies, we estimated tick burdens on 1965 wild ungulates in Doña… Leer más







Próximamente en Investigación
Publicaciones Científicas
Últimas publicadas
Últimas líneas de investigación
Science Publication
Indicators
ISI Scientific Publications
Total Last 60 mo. Last 12 mo.
1 ZTA 238 SUAT 56 ICM 20
2 ICM 227 ZTA 55 MYC 9
3 MYC 211 MYC 52 SAP 8
4 SUAT 199 ICM 41 SUAT 8
5 NED 73 SAP 19 ZTA 7
  VISAVET 1044 309 61

Impact Factor Average
Total Last 60 mo. Last 12 mo.
1 SAP 5.867 SAP 6.833 SAP 11.077
2 ZTA 3.876 ZTA 5.138 ICM 4.617
3 SUAT 2.91 ICM 4.182 NED 4.521
4 MYC 2.798 SUAT 4.072 ZTA 4.503
5 DICM 2.776 NED 3.561 SUAT 4.316
VISAVET 3.218 4.573 5.738

ISI Scientific Publications
Total Last 60 mo.
1 Vet Microbiol 87 Transbound Emerg Dis 38
2 Transbound Emerg Dis 87 Front Vet Sci 38
3 Prev Vet Med 74 Prev Vet Med 19
4 PLoS ONE 54 PLoS ONE 16
5 Front Vet Sci 53 Res Vet Sci 14
  All journals 344   All journals 40

PhD Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 24 MYC 3 NED 1
2 ZTA 23 NED 3 SUAT 1
3 MYC 13 SUAT 3 SEVISEQ 1
4 ICM 11 ZTA 2
5 NED 8 SEVISEQ 2
  VISAVET 90 16 4

Master Thesis
Total Last 60 mo. Last 12 mo.
1 SUAT 17 MYC 1
2 ZTA 14 NED 1
3 MYC 10 ZTA 1
4 NED 7
5 ICM 7
  VISAVET 58 4 0