Inicio \ Investigación \ Publicaciones científicas


Últimas publicaciones científicas SCI

4 de diciembre de 2018

Antimicrobial Prescriptions for Dogs in the Capital of Spain

Frontiers In Veterinary Science 5:309.

     Objective: To characterize antimicrobial prescription patterns for dogs in veterinary practices in Spain using the city of Madrid as a model.
Design: Retrospective survey.
Settings: Dogs attending veterinary practices in the city of Madrid in 2017 were enrolled.
Subjects: Three hundred dogs from 30 veterinary practices randomly selected from a set of 388 practices grouped by zip code. The inclusion criterion for dogs was treatment with antibiotics within a few days of the data collection day.
Results: For the 300 dogs enrolled, 374 treatments with antimicrobials were recorded, 62.8% (235/374) were veterinary medicinal products and 37.2% (139/374) human medicinal products. The main route of administration was oral… Leer más

Gomez-Poveda B. y Moreno MA..

28 de noviembre de 2018

Spatio-temporal epidemiology of anthrax in Hippopotamus amphibious in Queen Elizabeth Protected Area, Uganda

PLoS ONE 13(11): e0206922.

     Background
Anthrax is a zoonotic disease primarily of herbivores, caused by Bacillus anthracis, a bacterium with diverse geographical and global distribution. Globally, livestock outbreaks have declined but in Africa significant outbreaks continue to occur with most countries still categorized as enzootic, hyper endemic or sporadic. Uganda experiences sporadic human and livestock cases. Severe large-scale outbreaks occur periodically in hippos (Hippopotamus amphibious) at Queen Elizabeth Protected Area, where in 2004/2005 and 2010 anthrax killed 437 hippos. Ecological drivers of these outbreaks and potential of hippos to maintain anthrax in the ecosystem remain unknown. This study aimed to describe spatio-temporal patterns of anthrax… Leer más

Dicriu M., Rwego IB., Asiimwe B., Travis DA., Alvarez J., VanderWaal K. y Pelican K.

28 de noviembre de 2018

Evaluation of the McLintock syringe as a cause of non-specific reactions in the intradermal tuberculin test used for the diagnosis of bovine tuberculosis

Research In Veterinary Science 122(2019)175-178.

     The objective of this study was to elucidate whether the use of the McLintock syringe, used to inject tuberculin in cattle in several countries and based on an intradermal inoculation by needle, may, in itself, cause skin reactions that can be interpreted as positive reactions regardless of the real tuberculosis (TB) infection status of the animals.
Forty-four cattle from an officially TB-free (OTF) herd were selected for the experiment. Each animal received four inoculations [one with sterile phosphate buffer saline (PBS) with 10% of glycerol and three with bovine purified protein derivative (PPD), as performed during the single intradermal tuberculin (SIT) test], two on each side of the neck (n=176 inoculations). Three different Mc… Leer más

Roy A., Diez-Guerrier A., Ortega J., de la Cruz ML., Saez JL., Dominguez L., de Juan L., Alvarez J. y Bezos J..

21 de noviembre de 2018

Development and characterization of mouse monoclonal antibodies to eight human complement components: analysis of reactivity with orthologs of nine mammalian genera

Comparative Immunology, Microbiology And Infectious Diseases 62(2019):7-12.

     Abstract
To study complement function in mammalian leishmanioses, we developed mouse monoclonal antibodies to the human complement system components C1q, C4, factor D, factor H, factor B, properdin, C5 and C9. Antibody specificity was determined by indirect and capture ELISA and by Western blot. In flow cytometry analysis, seven antibodies recognized the cognate component on human serum-opsonized Leishmania promastigotes. Antibody reactivity was screened against promastigotes opsonized with sera of nine mammalian genera: pig, guinea pig, goat, rabbit, cat, dog, hamster, jird and rat. No antibody recognized jird epitopes on promastigotes. Anti-C4, -properdin, and -C5b reacted with the orthologous protein of all other mammals tested ex… Leer más

Monedero M., Infantes-Lorenzo JA., Moreno I., Martin AB., Macias RIR., Torano A. y Dominguez M.

1 de noviembre de 2018

Rapid differentiation of Staphylococcus aureus subspecies based on MALDI-TOF MS profiles

Journal Of Veterinary Diagnostic Investigation 30(6):813-820.

     Staphylococcus aureus encompasses 2 subspecies ( aureus and anaerobius) with significant differences in their epidemiology and pathogenicity. We evaluated the suitability of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF MS) for the rapid identification of both subspecies using a panel of 52 S. aureus isolates (30 subsp. anaerobius and 22 subsp. aureus) recovered from different origins, countries, and years. The on-board library identification system correctly identified 42 of 52 (81%) S. aureus isolates at the species level with score values >2.0. Limited performance was observed for differentiation of S. aureus subspecies (particularly subsp. anaerobius). Visual inspection of MALDI-TOF MS profiles … Leer más

Perez-Sancho M., Vela AI., Horcajo P., Ugarte-Ruiz M., Dominguez L., Fernandez-Garayzabal JF. y de la Fuente R.

1 de noviembre de 2018

Epidemiological surveillance of Mycobacterium tuberculosis complex in extensively raised pigs in the south of Spain

Preventive Veterinary Medicine 159(2018)87-91.

     The role of domestic pigs in the epidemiology of Mycobacterium tuberculosis complex (MTC) is considered to be limited due to the characteristics of intensive production systems. However, in southwestern Spain, Iberian pigs are usually raised under extensive management systems, sharing their habitat with other domestic and wild species, some of which may act as reservoirs of MTC. Our objective was to determine the seroprevalence, risk factors, spatial distribution and spoligotypes of MTC circulating in extensively farmed pigs in Andalusia (southern Spain), a region with a high prevalence of tuberculosis in both cattle and wild boar populations. Serum samples from 3622 extensively-raised Iberian pigs from 129 randomly selected farms were test… Leer más

Cano-Terriza D., Risalde MA., Rodriguez-Hernandez P., Napp S., Fernandez-Morente M., Moreno I., Bezos J., Fernandez-Molera V., Saez JL. y Garcia-Bocanegra I.

1 de noviembre de 2018

Use of processing fluids and serum samples to characterize porcine reproductive and respiratory syndrome virus dynamics in 3 day-old pigs

Veterinary Microbiology 225(2018):149-156.

     Collection of serum samples of pigs at weaning to monitor for porcine reproductive and respiratory syndrome virus (PRRSV) has become a common practice to determine PRRSV herd infection status. Diagnostic sensitivity of this practice is low in herds undergoing PRRSV elimination once prevalence of infection is near zero. Thus, the goal of this study was to characterize the dynamics of PRRSV infection in 3 day-old pigs overtime using serum and serosanguineous fluids obtained as part of castration and tail docking practices (processing fluids (PF)). Secondary goal was to estimate sensitivity and specificity of PF in the 3 day old population. A 6000 breed-to-wean sow herd was monitored every three weeks for 23 weeks after a PRRSV outbreak by col… Leer más

Vilalta C., Sanhueza J., Alvarez J., Murray D., Torremorell M., Corzo C. y Morrison R.

24 de octubre de 2018

Current concepts and contents of Veterinary Public Health and Veterinary Health Polic

Revista Española De Salud Pública 92:e201810077.

     Human and veterinary medicine obviously share most concepts and contents. However, both academic and scientific issues and the daily practice of many health disciplines can differ largely between human and veterinary medicine. Such differences can easily go unnoticed among other healthcare collectives or the general public. The aim of the present work was to provide an update, as well as some definitions of what we understand under the terms Veterinary Public Health and Veterinary Health Policy… Leer más

Briones V., Bezos J. y Alvarez J..

23 de octubre de 2018

Ant(6)-I genes encoding aminoglycoside O-nucleotidyltransferases are widely spread among streptomycin resistant strains of Campylobacter jejuni and Campylobacter coli

Frontiers In Microbiology 9:2515.

     Thermotolerant Campylobacter species C. jeuni and C. coli are actually recognized as the major bacterial agent responsible for food-transmitted gastroenteritis. The most effective antimicrobials against Campylobacter are macrolides and some, but not all aminoglycosides. Among these, susceptibility to streptomycin is reduced by mutations in the ribosomal RPSL protein or by expression of ANT(6)-I aminoglycoside O-nucleotidyltransferases. The presence of streptomycin resistance genes was evaluated among streptomycin-resistant Campylobacter isolated from humans and animals by using PCR with degenerated primers devised to distinguish ant(6)-Ia, ant(6)-Ib and other ant-like genes. Genes encoding ANT(6)-I enzymes were found in all possible combina… Leer más

Hormeno L., Ugarte-Ruiz M., Palomo G., Borge C., Vadillo S., Piriz S., Dominguez L., Campos MJ. y Quesada A.

5 de octubre de 2018

Pathologic findings and causes of death of stranded cetaceans in the Canary Islands (2006-2012)

PLoS ONE 13(10): e0204444.

     This study describes the pathologic findings and most probable causes of death (CD) of 224 cetaceans stranded along the coastline of the Canary Islands (Spain) over a 7-year period, 2006-2012. Most probable CD, grouped as pathologic categories (PCs), was identified in 208/224 (92.8%) examined animals. Within natural PCs, those associated with good nutritional status represented 70/208 (33.6%), whereas, those associated with significant loss of nutritional status represented 49/208 (23.5%). Fatal intra- and interspecific traumatic interactions were 37/208 (17.8%). Vessel collisions included 24/208 (11.5%). Neonatal/perinatal pathology involved 13/208 (6.2%). Fatal interaction with fishing activities comprised 10/208 (4.8%). Within anthropoge… Leer más

Diaz-Delgado J., Fernandez A., Sierra E., Sacchini S., Andrada M., Vela AI., Quesada-Canales O., Paz Y., Zucca D., Groch K. y Arbelo M.





Science Publication
Indicators
ISI Scientific Publications
Total Last 60 mo. Last 12 mo.
1 ZTA 193 ZTA 74 MYC 14
2 ICM 192 SUAT 66 ZTA 14
3 MYC 174 MYC 62 SUAT 12
4 SUAT 156 ICM 38 ICM 6
5 NED 65 NED 13 SEC 5
  VISAVET 781 268 53

Impact Factor Average
Total Last 60 mo. Last 12 mo.
1 ZTA 3.488 ZTA 3.589 ZTA 4.107
2 DICM 2.766 DICM 2.766 ICM 3.001
3 MYC 2.549 ICM 2.479 DICM 2.766
4 SUAT 2.444 SUAT 2.41 SUAT 2.633
5 ICM 2.302 SAP 2.195 NED 2.171
VISAVET 2.623 2.616 2.787

ISI Scientific Publications
Total Last 60 mo.
1 Vet. Microbiol. 61 Transbound. Emerg. Dis. 26
2 Transbound. Emerg. Dis. 39 Res. Vet. Sci. 20
3 J. Clin. Microbiol. 38 Vet. Microbiol. 15
4 Res. Vet. Sci. 33 PLoS ONE 15
5 Int. J. Syst. Evol. Microbiol. 32 BMC Vet. Res 13
  All journals 212   All journals 31