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May, 2018 news


May 29th, 2018

Via publiDB


Premio Nacional de Resistencia a Antibióticos para el profesor Bruno González Zorn

Interview in Tribuna Complutense of Tribuna Complutense




May 24th, 2018

Via publiDB


Nuevos determinantes de la resistencia a la colistina en Escherichia coli de origen animal

Conference in XXII Congreso de la Sociedad Española de Enfermedades Infecciosas y Microbiología Clínica




May 23rd, 2018

Via publiDB


Research in Veterinary Science

Evaluation of the use of a needle-free injection syringe as a cause of non-specific reactions in the intradermal tuberculin test used for the diagnosis of bovine tuberculosis

Investigation article published in Research in Veterinary Science


The objective of the study was to elucidate whether the use of the needle-free Dermojet syringe, which is based on a high pressure inoculation and is used to inject tuberculin in cattle in several countries, may, in itself, cause skin reactions that can be interpreted as positive reactions to the intradermal tests that are not, in fact, related to the real infection status of the animals. Forty-four cattle from an officially tuberculosis-free (OTF) herd were selected, and four single intradermal tuberculin (SIT) tests were performed on each animal, two on each side of the neck. Three differen… Read more




May 17th, 2018

Via publiDB


Preventive Veterinary Medicine

Temporal analysis of the interference caused by paratuberculosis vaccination on the tuberculosis diagnostic tests in goats

Investigation article published in Preventive Veterinary Medicine


Vaccination against paratuberculosis (PTB) in goats is a cost-effective control strategy, and is also effective as regards preventing the onset of clinical cases. However, it causes interference in the diagnostic tests used in the control of tuberculosis (TB). A group of 99 goats from a herd with no history of TB or PTB infection was vaccinated against PTB at seven months of age. They then underwent consecutive intradermal tests [single (SIT) and comparative (CIT) intradermal tuberculin tests), interferon-gamma release assays (IGRA) and two serological tests (p22_CE and DR-ELISA) every three m… Read more




May 17th, 2018

Vía lavanguardia.com


La producción de carne de ovino y caprino en Canarias aumenta un 19,5% entre 2015 y 2017

Apoyo a las Producciones Agrarias de Canarias


La producción de carne de ovino y caprino en Canarias se ha incrementado un 19,5 por ciento entre 2015 y 2017, debido principalmente a la modificación introducida en el Programa Comunitario de Apoyo a las Producciones Agrarias de Canarias (Posei) propuesta por el Ejecutivo canario, que prima la producción sobre otros aspectos…




May 15th, 2018

Via publiDB


Genetic dissection of the BRCA2 promoter and transcriptional impact of DNA variants

Breast cancer research and treatment publish this investigation article


Purpose Promoter mutations may affect transcription and can be associated with human diseases. However, the promoters of the breast cancer (BC) genes are not regularly screened. Our goal was to investigate the BRCA2 promoter in order to study a possible correlation between impaired transcription and disease. Methods The proximal and core promoter of the BRCA2 gene was sequenced in 95 high-risk BC patients. A BRCA2-promoter insert [− 938 to + 312 from the transcription start site (TSS)] was generated and cloned into the firefly luciferase vector pGL4.10. Promoter variants and del… Read more




May 12nd, 2018

Via publiDB


PSA: nuove tecniche di diagnosi, di azione e strategie di controllo

Conference in Suinicoltura 2.0. Innovazione nella tradizione l´alba di un nuovo sviluppo




May 10th, 2018

Via publiDB


Use of free-range pigs as sentinels for animal tuberculosis in Spain

Poster communication in 10th European Symposium of Porcine Health Management (ESPHM)




May 2nd, 2018

Via publiDB


Testing the Role of Multicopy Plasmids in the Evolution of Antibiotic Resistance

Journal of visualized experiments : JoVE publish this investigation article


Multicopy plasmids are extremely abundant in prokaryotes but their role in bacterial evolution remains poorly understood. We recently showed that the increase in gene copy number per cell provided by multicopy plasmids could accelerate the evolution of plasmid-encoded genes. In this work, we present an experimental system to test the ability of multicopy plasmids to promote gene evolution. Using simple molecular biology methods, we constructed a model system where an antibiotic resistance gene can be inserted into Escherichia coli MG1655, either in the chromosome or on a multicopy plasmid. We … Read more




May 1st, 2018

Via publiDB


Veterinary Immunology and Immunopathology

The use of serological tests in combination with the intradermal tuberculin test maximizes the detection of tuberculosis infected goats

Veterinary Immunology and Immunopathology publish this investigation article


The diagnosis of tuberculosis (TB) in goats is based mainly on the single and comparative intradermal tuberculin (SIT and CIT) tests and, exceptionally, on the interferon-gamma (IFN-γ) assay, however they are not perfect in terms of sensitivity and specificity. Nevertheless, various serological assays that provide a potential cost-effective approach for the control of TB are also available or under development, and a variety of results have been reported regarding the ability of these tests to detect infected animals, particularly in the early stages of infection. In the present study, S… Read more




May 1st, 2018

Via publiDB


International Journal of Systematic and Evolutionary Microbiology

Streptococcus penaeicida sp. nov., isolated from a diseased farmed Pacific white shrimp (Penaeus vannamei)

Investigation published in International Journal of Systematic and Evolutionary Microbiology


Strain CAIM 1838T, isolated from the hepatopancreas of a cultured diseased Pacific white shrimp (Penaeusvannamei), was subjected to characterization by a polyphasic taxonomic approach. On the basis of 16S rRNA gene sequence analysis, strain CAIM 1838T was most closely related to Streptococcus bovimastitidis 99.3 % and to other species of the Pyogenes clade of Streptococcus with lower similarity values. Average nucleotide identity values and the genome-to-genome distance of strain CAIM 1838T, as compared with the type strains, confirmed the separate species status with closely related spe… Read more




May 1st, 2018

Via publiDB


Oxford University Press

Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

Investigation published in The Journal of Antimicrobial Chemotherapy


Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer through plasmids plays a major role. The identification of plasmid characteristics and their association with different bacterial hosts provides crucial knowledge that is essential to understand the contribution of plasmids to the transmission of AMR determinants. Molecular identification of plasmid and strain genotypes elicits a distinction between spread of AMR genes by plasmids and dissemination of these genes by spread of bacterial clones. For this reason several methods are used to type the plasmi… Read more




May 1st, 2018

Via publiDB


Transboundary and Emerging Diseases

Gaps in African swine fever: Analysis and priorities

Investigation published in Transboundary and Emerging Diseases


African swine fever (ASF) causes greater sanitary, social and economic impacts on swine herds than many other swine diseases. Although ASF was first described in 1921 and it has affected more than fifty countries in Africa, Europe and South America, several key issues about its pathogenesis, immune evasion and epidemiology remain uncertain. This article reviews the main characteristics of the causative virus, its molecular epidemiology, natural hosts, clinical features, epidemiology and control worldwide. It also identifies and prioritizes gaps in ASF from a horizontal point of view encompassi… Read more




May 1st, 2018

Via publiDB


Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation

Nature Ecology & Evolution publish this article


Understanding the mechanisms governing innovation is a central element of evolutionary theory. Novel traits usually arise through mutations in existing genes, but trade-offs between new and ancestral protein functions are pervasive and constrain the evolution of innovation. Classical models posit that evolutionary innovation circumvents the constraints imposed by trade-offs through genetic amplifications, which provide functional redundancy. Bacterial multicopy plasmids provide a paradigmatic example of genetic amplification, yet their role in evolutionary innovation remains largely unexplored… Read more







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