Noise, Memory, and Antibiotic Resistance
Oral communication in Seminarios VISAVET 2024
October 10th, 2024
Pena-Miller R.
This talk explores how phenotypic noise mediated by multicopy plasmids enables bacteria to survive in hostile and unpredictable environments. Combining experimental evolution with mathematical modeling, we examine how these dynamics lead to transient resistance — a temporary ability to tolerate lethal antibiotic concentrations without the acquisition of mutations. We will also discuss adaptive memory, a mechanism that allows bacteria to remember past exposures and respond more effectively to future challenges
Centro de Ciencias Genómicas. Universidad Nacional Autónoma de México (UNAM). | |
Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |
Link to Seminars VISAVET 2024