Emergent subtype of hepatitis E virus genotype 3 in wild boar in Spain
Transboundary and Emerging Diseases publica este artículo de investigación
24 de septiembre de 2019
Wild boar (Sus scrofa) is considered the main wildlife reservoir of zoonotic hepatitis E virus (HEV) genotypes. The aim of this study was to evaluate the circulation of HEV in free-ranging wild boar in the Doñana National Park (DNP), Spain. Blood samples were collected from 99 wild boar in the DNP during 2015. Sera were analyzed in parallel using indirect ELISA and real-time RT-PCR. A total of 57 of the 99 tested animals (57.6%; 95%CI: 47.8-67.3%) had anti-HEV antibodies, indicating that this virus is widespread in wild boar in the DNP. HEV RNA was detected in one animal and phylogenetic analysis showed that the sequence isolated belonged to subtype 3r. The results suggest a potential risk of zoonotic transmission of this novel HEV-3 subtype, which could be of public health concern. Further studies are required to assess the role of wild boar in the epidemiology of HEV-3r and to determine the infectivity of this emergent HEV subtype in other species, including humans. This article is protected by copyright. All rights reserved
Caballero-Gomez J., Jiménez-Ruiz S., Lopez-Lopez P., Vicente J., Risalde MA., Cano-Terriza D., Frias M., Barasona JA., Rivero A., Garcia-Bocanegra I. y Rivero-Juarez A.
 | Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad de Córdoba (UCO). |
 | Unidad de Enfermedades Infecciosas. Hospital Universitario Reina Sofía de Córdoba. Instituto Maimonides de Investigación Biomédica de Cordoba. |
 | Sanidad y Biotecnología (SaBio). Instituto de Investigación en Recursos Cinegéticos (IREC). Consejo Superior de Investigaciones Científicas (CSIC). Universidad de Castilla La Mancha (UCLM). Gobierno de Castilla-La Mancha (JCCM). |
| Departamento de Anatomía y Anatomía Patológica Comparadas. Facultad de Veterinaria. Universidad de Córdoba (UCO). |
 | Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
| Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
