Sheep as a Potential Source of Bovine TB: Epidemiology, Pathology and Evaluation of Diagnostic Techniques
Investigación publicada en Transboundary and Emerging Diseases
1 de diciembre de 2016
Bovine tuberculosis (TB) infection is infrequently diagnosed in sheep. Most reports are from single individual cases or flock outbreaks. However, in Spain several outbreaks have been reported recently, all of which had epidemiological links with TB-infected cattle herds. A total of 897 sheep suspected of being infected with TB and belonging to 23 flocks cohabiting with TB-infected cattle herds and/or goats were tested between 2009 and 2013 in Galicia (north-western Spain), using pathological, immunological and molecular techniques. Of these, 50.44% were positive by culture, 83.23% by histopathology and 24.92%, 4.86% and 59.42% by single intradermal tuberculin test (SITT), interferon-γ and ELISA, respectively. Results suggest that in circumstances akin to those in our study, sheep may be considered as a potential source of TB. We conclude that under similar conditions, serious consideration should be given to TB testing sheep, as they may represent a potential risk to other susceptible co-habiting species. The SITT and ELISA are recommended as the simplest and most cost-effective initial approaches for the diagnosis of TB in sheep under field conditions. However, when possible, interferon-γ should be applied to increase sensitivity
Munoz-Mendoza M., Romero B., del Cerro A., Gortazar C., Garcia-Marin JF., Menendez S., Mourelo J., de Juan L., Saez-Llorente JL., Delahay RJ. y Balseiro A.
Departamento de Biología Molecular del Laboratorio de Sanidad y Producción Animal de Galicia. Consellería do Medio Rural. Xunta de Galicia. | |
Servicio de Micobacterias (MYC). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |
Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). | |
Servicio Regional de Investigación y Desarrollo Agroalimentario (SERIDA). Gobierno del Principado de Asturias. | |
Sanidad y Biotecnología (SaBio). Instituto de Investigación en Recursos Cinegéticos (IREC). Consejo Superior de Investigaciones Científicas (CSIC). Universidad de Castilla La Mancha (UCLM). Gobierno de Castilla-La Mancha (JCCM). | |
Universidad de Castilla La Mancha (UCLM). | |
Gobierno de Castilla-La Mancha (JCCM). | |
Facultad de Veterinaria. Universidad de León. | |
Subdirección General de Sanidad e Higiene Animal y Trazabilidad. Dirección General de Sanidad de la Producción Agraria. Ministerio de Agricultura, Alimentación y Medio Ambiente (MAGRAMA). | |
Animal and Plant Health Agency (APHA). | |