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First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain

Investigation published in Enfermedades Infecciosas y Microbiología Clínica

August 31st, 2013

The rapid spread of Klebsiella pneumoniae carbapenemases (KPCs) in the last years represents a serious public health threat. KPCs have a great potential for spread due to their location on mobile genetic elements that are horizontally transferred and associated with widespread clones.1 Many KPC producing K. pneumoniae isolates are associated to a single sequence type (ST)258, a clonal lineage that has been causing epidemics of great proportions in various regions of USA, Israel, Greece and recently in other European countries.2, 3 Organisms carrying carbapenemases usually harbours resistance determinants to other antimicrobials and consequently infections due to these pathogens are difficult to treat which results in high associated morbidity




Valentin-Martin A., Valverde A., Bosque-Vall M. and Canton R.




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First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain

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First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain


Participants:

Servicio de Microbiología. Hospital Arnau de Vilanova.

Universidad ComplutenseServicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseFacultad de Veterinaria. Universidad Complutense (UCM).

Consejo Superior de Investigaciones CientíficasUnidad asociada de Resistencia a Antibióticos y Virulencia Bacteriana. Consejo Superior de Investigaciones Científicas (CSIC).

Comunidad de MadridInstituto Ramón y Cajal de Investigación Sanitaria (IRYCIS). Universidad Complutense (UCM). Universidad Autónoma de Madrid (UAM). Universidad de Alcalá (UAH). Salud Madrid. Comunidad de Madrid.







Enfermedades Infecciosas y Microbiología Clínica
FACTOR YEAR Q
1.881 2013

NLMID: 9104081

PMID: 23462465

ISSN: 0213-005X



TITLE: First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain


JOURNAL: Enferm. Infec. Microbiol. Clin.


NUMERACIÓN: 31(7):489-91


AÑO: 2013


PUBLISHER: Elsevier España, S.L.


AUTHORS: Valentin-Martin A., Valverde A., Bosque-Vall M. and Canton R.


DOI: https://doi.org/ 10.1016/j.eimc.2012.12.002


CITE THIS PUBLICATION:

Valentin-Martin A., Valverde A., Bosque-Vall M. and Canton R. First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain. Enfermedades Infecciosas y Microbiología Clínica. 31(7):489-91. 2013. (L). ISSN: 0213-005X. DOI: 10.1016/j.eimc.2012.12.002


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