First report of colistin-resistant KPC-2 producing ST258-Klebsiella pneumoniae in Spain
Investigation published in Enfermedades Infecciosas y Microbiología Clínica
August 31st, 2013
The rapid spread of Klebsiella pneumoniae carbapenemases (KPCs) in the last years represents a serious public health threat. KPCs have a great potential for spread due to their location on mobile genetic elements that are horizontally transferred and associated with widespread clones.1 Many KPC producing K. pneumoniae isolates are associated to a single sequence type (ST)258, a clonal lineage that has been causing epidemics of great proportions in various regions of USA, Israel, Greece and recently in other European countries.2, 3 Organisms carrying carbapenemases usually harbours resistance determinants to other antimicrobials and consequently infections due to these pathogens are difficult to treat which results in high associated morbidity
Valentin-Martin A., Valverde A., Bosque-Vall M. and Canton R.
| Servicio de Microbiología. Hospital Arnau de Vilanova. | |
 | Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
| Facultad de Veterinaria. Universidad Complutense (UCM). |
 | Unidad asociada de Resistencia a Antibióticos y Virulencia Bacteriana. Consejo Superior de Investigaciones Científicas (CSIC). |
 | Instituto Ramón y Cajal de Investigación Sanitaria (IRYCIS). Universidad Complutense (UCM). Universidad Autónoma de Madrid (UAM). Universidad de Alcalá (UAH). Salud Madrid. Comunidad de Madrid. |
