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Global emergence and evolutionary dynamics of bluetongue virus

Investigation published in Scientific reports

December 10th, 2020

Bluetongue virus (BTV) epidemics are responsible for worldwide economic losses of up to US$ 3 billion. Understanding the global evolutionary epidemiology of BTV is critical in designing intervention programs. Here we employed phylodynamic models to quantify the evolutionary characteristics, spatiotemporal origins, and multi-host transmission dynamics of BTV across the globe. We inferred that goats are the ancestral hosts for BTV but are less likely to be important for cross-species transmission, sheep and cattle continue to be important for the transmission and maintenance of infection between other species. Our models pointed to China and India, countries with the highest population of goats, as the likely ancestral country for BTV emergence and dispersal worldwide over 1000 years ago. However, the increased diversification and dispersal of BTV coincided with the initiation of transcontinental livestock trade after the 1850s. Our analysis uncovered important epidemiological aspects of BTV that may guide future molecular surveillance of BTV




Alkhamis M., Aguilar-Vega C., Fountain-Jones NM., Lin K., Perez AM. and Sanchez-Vizcaino JM..




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Global emergence and evolutionary dynamics of bluetongue virus

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Global emergence and evolutionary dynamics of bluetongue virus


Participants:

Faculty of Public Heath. Health Sciences Centre. Kuwait University.

Universidad ComplutenseServicio de Inmunología Viral y Medicina Preventiva (SUAT). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

University of MinnesotaDepartment of Veterinary Population Medicine. College of Veterinary Medicine. University of Minnesota (UMM).

University of Tasmania (UTAS).







Scientific reports
FACTOR YEAR Q
3.998 2019

NLMID: 101563288

PMID: 33303862

ISSN: 2045-2322



TITLE: Global emergence and evolutionary dynamics of bluetongue virus


JOURNAL: Sci Rep


NUMERACIÓN: 10(1):21677


AÑO: 2020


PUBLISHER: London : Nature Publishing Group, copyright 2011


AUTHORS: Alkhamis M., Aguilar-Vega C., Fountain-Jones NM., Lin K., Perez AM. and Sanchez-Vizcaino JM..


VISAVET PARTICIPANTS


2nd
Cecilia Aguilar Vega
Last
José Manuel Sánchez-Vizcaíno Rodríguez

DOI: https://doi.org/ 10.1038/s41598-020-78673-9


CITE THIS PUBLICATION:

Alkhamis M., Aguilar-Vega C., Fountain-Jones NM., Lin K., Perez AM. and Sanchez-Vizcaino JM. Global emergence and evolutionary dynamics of bluetongue virus. Scientific reports. 10(1):21677. 2020. (A). ISSN: 2045-2322. DOI: 10.1038/s41598-020-78673-9


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