Conference in XVII Congreso de Investigación de Estudiantes de Grado en Ciencias de la Salud. XXI Congreso de Ciencias Veterinarias y Biomédicas. II Congreso de Ciencias Experimentales en el Campo de la Salud

April 3^rd, 2025

Aradilla-Macias N., de Pablo-Moreno J., Arribas-Mercado A. and Porras N.

Species of the suborder Strepsirhini (primitive primates) represent animal models of great value for the study of comparable diseases in humans due to their phylogenetic proximity. However, their conservation status often restricts their use in research, which has resulted in a sparse scientific literature on this unique group of primates. A greater effort in the characterization of their pathologies is essential for their conservation and management in captivity. Although sporadic cases of neoplasms have been documented in lemurs, these have been mainly isolated reports, and knowledge about neoplastic diseases in these animals remains limited. In this study, various organs of a 20-year-old male ring-tailed lemur (Lemur catta), submitted to the Animal Pathology and Forensic Veterinary Service of the VISAVET center, with respiratory distress and lethargy, were analyzed. Radiographic, ultrasound and computed tomography studies revealed a left intrathoracic mass, initially compatible with an abscess. During anesthesia, the animal died due to lung compression induced by the mass. Histological and immunohistochemical analysis revealed splenic histiocytic sarcoma with metastases in lymph nodes, intercostal muscle, diaphragm and kidney. The intrathoracic mass corresponded to a metastasis of the splenic histiocytic sarcoma, with possible secondary septic contamination. In addition, chronic kidney disease, multifocal necrotizing hepatitis, suppurative bronchopneumonia associated with the mass, pancreatic adenoma, and multiple multiorgan perivascular inflammatory infiltrates compatible with a septicemic process, among others, were identified. Neoplasms in Lemur catta have been poorly documented, with little previous history of this condition in the species. This study depths the knowledge about possible neoplasms in lower primates, characterizing a case of metastatic histiocytic sarcoma, and providing relevant information for its conservation

	Servicio de Patología y Veterinaria Forense (SAP). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).