MCR-2-mediated plasmid-borne polymyxin resistance most likely originates from Moraxella pluranimalium
The Journal of Antimicrobial Chemotherapy publish this investigation article
October 1st, 2017
The recent identification of the first plasmid-mediated polymyxin resistance determinants, namely the MCR-1 and MCR-2 enzymes, has constituted an ultimate threat of pandrug resistance in Gram-negative organisms.1–3 These enzymes have been reported only in Enterobacteriaceae, mainly in Escherichia coli and Klebsiella pneumoniae; however, there have been reports from other enterobacterial genera, including Enterobacter, Salmonella and Shigella.1 The mcr-1 and mcr-2 genes have both been identified from cattle and pigs.1–3 In addition, the mcr-1 gene has been identified from chickens,4 but also from river samples and vegetables
Poirel L., Kieffer N., Fernandez-Garayzabal JF., Vela AI., Larpin Y. and Nordmann P.
| Department of Medicine. Faculty of Science. University of Fribourg (UNIFR). | |
 | Servicio de Identificación y Caracterización Microbiana (ICM). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
| Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
