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Natural Bagaza virus infection in game birds in southern Spain

Investigation article published in Veterinary Research

September 11st, 2012

In late summer 2010 a mosquito born flavivirus not previously reported in Europe called Bagaza virus (BAGV) caused high mortality in red-legged partridges (Alectoris rufa) and ring-necked pheasants (Phasianus colchicus). We studied clinical findings, lesions and viral antigen distribution in naturally BAGV infected game birds in order to understand the apparently higher impact on red-legged partridges. The disease induced neurologic signs in the two galliform species and, to a lesser extent, in common wood pigeons (Columba palumbus). In red-legged partridges infection by BAGV caused severe haemosiderosis in the liver and spleen that was absent in pheasants and less evident in common wood pigeons. Also, BAGV antigen was present in vascular endothelium in multiple organs in red-legged partridges, and in the spleen in common wood pigeons, while in ring-necked pheasants it was only detected in neurons and glial cells in the brain. These findings indicate tropism of BAGV for endothelial cells and a severe haemolytic process in red-legged partridges in addition to the central nervous lesions that were found in all three species.




Gamino V., Gutierrez-Guzman AV., Fernandez de Mera IG., Ortiz JA., Duran-Martin M., de la Fuente J., Gortazar C. and Hofle U.




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Natural Bagaza virus infection in game birds in southern Spain

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Natural Bagaza virus infection in game birds in southern Spain



Participants:

Universidad ComplutenseServicio de Micobacterias (MYC). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Gobierno de Castilla-La ManchaSanidad y Biotecnología (SaBio). Instituto de Investigación en Recursos Cinegéticos (IREC). Consejo Superior de Investigaciones Científicas (CSIC). Universidad de Castilla La Mancha (UCLM). Gobierno de Castilla-La Mancha (JCCM).

Medianilla S.L.Medianilla S.L..







Veterinary Research
FACTOR YEAR Q
3.426 2012

NLMID: 9309551

PMID: 22966904

ISSN: 0928-4249



TITLE: Natural Bagaza virus infection in game birds in southern Spain


JOURNAL: Vet. Res.


NUMERACIÓN: 43(1):65


AÑO: 2012


PUBLISHER: BMC


AUTHORS: Gamino V., Gutierrez-Guzman AV., Fernandez de Mera IG., Ortiz JA., Duran-Martin M., de la Fuente J., Gortazar C. and Hofle U.


DOI: https://doi.org/10.1186/1297-9716-43-65


CITE THIS PUBLICATION:

Gamino V., Gutierrez-Guzman AV., Fernandez de Mera IG., Ortiz JA., Duran-Martin M., de la Fuente J., Gortazar C. and Hofle U. Natural Bagaza virus infection in game birds in southern Spain. Veterinary Research. 43(1):65. 2012. (A). ISSN: 0928-4249. DOI: 10.1186/1297-9716-43-65


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