Home \ Research \ Scientific publications \


Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

Investigation published in The Journal of Antimicrobial Chemotherapy

May 1st, 2018

Bacterial antimicrobial resistance (AMR) is constantly evolving and horizontal gene transfer through plasmids plays a major role. The identification of plasmid characteristics and their association with different bacterial hosts provides crucial knowledge that is essential to understand the contribution of plasmids to the transmission of AMR determinants. Molecular identification of plasmid and strain genotypes elicits a distinction between spread of AMR genes by plasmids and dissemination of these genes by spread of bacterial clones. For this reason several methods are used to type the plasmids, e.g. PCR-based replicon typing (PBRT) or relaxase typing. Currently, there are 28 known plasmid types in Enterobacteriaceae distinguished by PBRT. Frequently reported plasmids [IncF, IncI, IncA/C, IncL (previously designated IncL/M), IncN and IncH] are the ones that bear the greatest variety of resistance genes. The purpose of this review is to provide an overview of all known AMR-related plasmid families in Enterobacteriaceae, the resistance genes they carry and their geographical distribution




Rozwandowicz M., Brouwer MSM., Fischer J., Wagenaar J., Gonzalez-Zorn B., Guerra B., Mevius DJ. and Hordijk J.




See this article
Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

See it on NLM PubMed
Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae

Participants:

Utrecht UniversityDepartment of Infectious Diseases and Immunology. Faculty of Veterinary Medicine. Utrecht University (UU).

Wageningen Bioveterinary Research.

Federal Institute for Risk AssessmentDepartment of Biological Safety. Federal Institute for Risk Assessment (BfR).

Universidad ComplutenseServicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).







The Journal of Antimicrobial Chemotherapy
FACTOR YEAR Q
5.217 2017

NLMID: 7513617

PMID: 29370371

ISSN: 0305-7453



TITLE: Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae


JOURNAL: J. Antimicrob. Chemother.


NUMERACIÓN: 73(5):1121-1137


AÑO: 2018


PUBLISHER: Oxford University Press


AUTHORS: Rozwandowicz M., Brouwer MSM., Fischer J., Wagenaar J., Gonzalez-Zorn B., Guerra B., Mevius DJ. and Hordijk J.


VISAVET PARTICIPANTS


Bruno González Zorn

DOI: https://doi.org/ 10.1093/jac/dkx488


CITE THIS PUBLICATION:

Rozwandowicz M., Brouwer MSM., Fischer J., Wagenaar J., Gonzalez-Zorn B., Guerra B., Mevius DJ. and Hordijk J. Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae. The Journal of Antimicrobial Chemotherapy. 73(5):1121-1137. 2018. (A). ISSN: 0305-7453. DOI: 10.1093/jac/dkx488


UNITS: