Potential use of dietary fibre from Hibiscus sabdariffa and Agave tequilana in obesity management
Journal of Functional Foods publish this investigation article
March 1st, 2016
The anti-obesity potential of dietary fibre (DF) from Hibiscus sabdariffa (ground calyces) and Agave tequilana (agave-fructans) as an additive in the feed of animals subjected to a high fat diet was examined. Over a 5-week period, the effects of each DF alone, and in combination, were examined with respect to food intake, weight gain, adiposity, plasma metabolic profile, appetite regulation and inflammatory biomarkers in white and brown adipose tissue. Supplementation with the ground H. sabdariffa calyces was associated with a reduction in body weight, adiposity, plasma total cholesterol and glucose. As novel findings, the addition of H. sabdariffa increased plasma GLP1, reduced proinflammatory cytokines in white adipose tissue and increased IL6 in brown adipose tissue; it therefore appears to be a promising source of functional DF. These effects were partially maintained when H. sabdariffa was supplied in combination with A. tequilana DF and were independent of appetite reduction
Moyano G., Sayago-Ayerdi SG., Largo C., Caz V., Santamaria M. and Tabernero M.
 | Departamento de Cirugía Experimental. Instituto de Investigación Hospital La Paz (IdiPAZ). Consejería de Sanidad. Comunidad de Madrid. |
 | Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
| Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
 | Laboratorio Integral de Investigación en Alimentos. Instituto Tecnológico de Tepic. |
