Trends and Challenges in the Detection and Environmental Surveillance of the Hepatitis E Virus
Investigation published in Microorganisms
April 26th, 2025
The Hepatitis E virus (HEV) is responsible for causing Hepatitis E, a zoonotic disease that has emerged as a significant global health concern, accounting for about 20 million infections and 70,000 deaths annually. Although it is often recognized as a disease that is acute in low-income countries, HEV has also been recognized as a zoonotic disease in high-income countries. The zoonotic transmission requires flexible approaches to effectively monitor the virus, vectors, and reservoirs. However, the environmental monitoring of HEV presents additional challenges due to limitations in current detection methods, making it difficult to accurately assess the global prevalence of the virus. These challenges hinder efforts to fully understand the scope of the disease and to implement effective control measures. This review will explore these and other critical concerns, addressing gaps in HEV research and highlighting the need for improved strategies in the monitoring, prevention, and management of Hepatitis E using a One Health approach.
Alves-Elois M., Paula-Pavi C., Ferreira Souza-Hoffmann Jempierre Y., Von Tönnemann-Pilati G., Zanchetta L., Borges-da Silva Grisard H., Garcia N., Rodriguez-Lazaro D. and Fongaro G.
| Department of Microbiology. Immunology and Parasitology. Federal University of Santa Catarina. | |
 | Sección de Microbiología. Centro de patógenos emergentes y salud global. Facultad de Ciencias. Universidad de Burgos (UBU). |
 | Servicio de Zoonosis Emergentes, de Baja Prevalencia y Agresivos Biológicos (NED). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
| Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
