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Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada

Artículo de investigación publicado en Veterinary Research

9 de enero de 2018

Streptococcus suis is one of the most important bacterial pathogens in the porcine industry and also a zoonotic agent. Serotype 9 is becoming one of the most prevalent serotypes within the S. suis population in certain European countries. In the present study, serotype 9 strains isolated from a country where infection due to this serotype is endemic (Spain), were compared to those recovered from Canada, where this serotype is rarely isolated from diseased pigs. For comparison purposes, strains from Brazil and the only strain isolated from a human case, in Thailand, were also incorporated. Firstly, sequence types (STs) were obtained followed by detection of putative virulence factors. Phylogenetic trees were constructed using the non-recombinant single nucleotide polymorphisms from core genomes of tested strains. Most Spanish strains were either ST123 or ST125, whereas Canadian strains were highly heterogeneous. However, the distribution of putative virulence factors was similar in both groups of strains. The fact that ST16 strains harbored more putative virulence genes and shared greater similarity with the genome of human serotype 2 strains suggests that they present a higher zoonotic and virulence potential than those from Canada and Spain. More than 80% of the strains included in this study carried genes associated with resistance to tetracycline, lincosamides and macrolides. Serotype 9 strains may be nearly 400 years old and have evolved in parallel into 2 lineages. The rapid population expansion of dominant lineage 1 occurred within the last 40 years probably due to the rapid development of the porcine industry




Zheng H., Du P., Qiu X., Kerdsin A., Roy D., Bai X., Xu J., Vela AI. y Gottschalk M.




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Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada

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Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada



Participantes:

Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases. National Institute for Communicable Disease Control and Prevention. Chinese Center for Disease Control and Prevention (CDC).

Institute of Infectious Diseases. Beijing Ditan Hospital. Capital Medical University.

Faculty of Public Health. Kasetsart University Chalermphrakiat Sakon Nakhon Province Campus.

Centre de Recherche en Infectiologie Porcine (CRIP). Faculté de Médicine Vétérinaire. Université de Montréal (UM).

Universidad ComplutenseServicio de Identificación y Caracterización Microbiana (ICM). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).







FACTOR YEAR Q
3.117 2018

NLMID: 9309551

PMID: 29316972

ISSN: 0928-4249



TÍTULO: Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada


REVISTA: Vet Res


NUMERACIÓN: 49(1):1


AÑO: 2018


EDITORIAL: BMC


AUTORES: Zheng H., Du P., Qiu X., Kerdsin A., Roy D., Bai X., Xu J., Vela AI. and Gottschalk M.


PARTICIPANTES VISAVET


Ana Isabel Vela Alonso

DOI: https://doi.org/10.1186/s13567-017-0498-2


CITA ESTA PUBLICACIÓN:

Zheng H., Du P., Qiu X., Kerdsin A., Roy D., Bai X., Xu J., Vela AI. y Gottschalk M. Genomic comparisons of Streptococcus suis serotype 9 strains recovered from diseased pigs in Spain and Canada. Veterinary Research. 49(1):1. 2018. (A). ISSN: 0928-4249. DOI: 10.1186/s13567-017-0498-2


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