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Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication

Investigación publicada en Acta veterinaria Hungarica

16 de diciembre de 2019

Pasteurella multocida is responsible for economically important diseases in sheep and pigs. Antimicrobial susceptibility studies are essential for initiating rational and effective empirical therapy of P. multocida infections. In this study we investigated the antimicrobial susceptibility to 18 antimicrobial agents of 156 clinical isolates of P. multocida from sheep (n = 87) and pigs (n = 69) using the microdilution method. Both sheep and pig isolates exhibited low levels of resistance (≤ 15%) to ceftiofur, gentamicin, neomycin, spectinomycin, chlortetracycline, tulathromycin, florfenicol, danofloxacin, and enrofloxacin and trimethoprim/sulphamethoxazole, high resistance rates (> 15% up to 50%) to oxytetracycline, tilmicosin, and tiamulin, and very high resistance rates (> 50%) to tylosin tartrate, clindamycin, and sulphadimethoxine. However, sheep isolates exhibited significantly lower percentages of resistance and lower MIC90 values (P < 0.05) than pig isolates for most of the antimicrobials tested. In addition, sheep isolates exhibited also significantly lower phenotypic antimicrobial resistance diversity (8 resistotypes vs. 30 resistotypes). LAC-LIN-SUL-MAC was the resistotype most frequently detected in sheep (39.1%) and LIN-SUL-MAC in pig isolates (26.1%). The differences in susceptibility patterns could be influenced by the lower use of antimicrobials in the small ruminant industry compared with the pig farming industry




Cid D., Fernandez-Garayzabal JF., Pinto C., Dominguez L. y Vela AI..




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Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication

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Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication


Participantes:

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).

Universidad ComplutenseServicio de Identificación y Caracterización Microbiana (ICM). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

University of LondonRoyal Veterinary College. University of London.







Acta veterinaria Hungarica
FACTOR YEAR Q
1.059 2018

NLMID: 8406376

PMID: 31842595

ISSN: 0236-6290



TÍTULO: Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication


REVISTA: Acta Vet Hung


NUMERACIÓN: 67(4):489-498


AÑO: 2019


EDITORIAL: Budapest Akademiai Kiado


AUTORES: Cid D., Fernandez-Garayzabal JF., Pinto C., Dominguez L. and Vela AI..


PARTICIPANTES VISAVET


2nd
José Francisco Fernández-Garayzabal Fernández
4th
Lucas Domínguez Rodríguez
Last
Ana Isabel Vela Alonso

DOI: https://doi.org/10.1556/004.2019.048


CITA ESTA PUBLICACIÓN:

Cid D., Fernandez-Garayzabal JF., Pinto C., Dominguez L. y Vela AI. Antimicrobial susceptibility of Pasteurella multocida isolated from sheep and pigs in Spain - Short communication. Acta veterinaria Hungarica. 67(4):489-498. 2019. (A). ISSN: 0236-6290. DOI: 10.1556/004.2019.048


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