Identification of a New Genotype of African Swine Fever Virus in Domestic Pigs from Ethiopia
Artículo de investigación publicado en Transboundary and Emerging Diseases
1 de octubre de 2017
African swine fever (ASF) is an important emerging transboundary animal disease (TAD), which currently has an impact on many countries in Africa, Eastern Europe, the Caucasus and the Russian Federation. The current situation in Europe shows the ability of the virus to rapidly spread, which stands to threaten the global swine industry. At present, there is no viable vaccine to minimize spread of the disease and stamping out is the main source of control. In February 2011, Ethiopia had reported its first suspected outbreaks of ASF. Genomic analyses of the collected ASF virus (ASFV) strains were undertaken using 23 tissue samples collected from domestic swine in Ethiopia from 2011 to 2014. The analysis of Ethiopian ASFVs partial p72 gene sequence showed the identification of a new genotype, genotype XXIII, that shares a common ancestor with genotypes IX and X, which comprise isolates circulating in Eastern African countries and the Republic of Congo. Analysis of the p54 gene also followed the p72 pattern and the deduced amino acid sequence of the central variable region (CVR) of the B602L gene showed novel tetramer repeats not previously characterized
Achenbach JE., Gallardo C., Nieto-Pelegrin E., Rivera B., Degefa T., Arias M., Jenberie S., Mulisa DD., Gizaw D., Gelaye E., Chibssa TR., Belaye A., Loitsch A., Forsa M., Yami M., Diallo A., Soler A., Lamien CE. y Sanchez-Vizcaino JM..
Animal Production and Health Laboratory. Food and Agriculture Organization of the United Nations (FAO). | |
Division of Nuclear Techniques in Food and Agriculture. Department of Nuclear Sciences and Applications. International Atomic Energy Agency (IAEA). | |
Centro de Investigación en Sanidad Animal (CISA). Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA). | |
Servicio de Inmunología Viral y Medicina Preventiva (SUAT). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |
Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). | |
National Veterinary Institute or Ethiopia (NVI). | |
National Animal Health Diagnostic and Investigation Center (NAHDIC). | |
Institute for Veterinary Disease Control. Austrian Agency for Health and Food Safety (AGES). | |