Occurrence of extended-spectrum beta-lactamase-producing Salmonella enterica in northern Spain with evidence of CTX-M-9 clonal spread among animals and humans
Investigación publicada en Clinical Microbiology and Infection
1 de marzo de 2009
Among the 1233 Salmonella enterica isolates obtained in two Spanish hospitals, five isolates (0.4%) (serovars: Virchow, four; Livingstone, one) had the phenotype of an extended-spectrum beta-lactamase (ESBL) producer. The genetic characterization of the ESBL of S. enterica Livingstone revealed a bla(SHV-2) gene. The bla(CTX-M-10) gene in a phage-related genetic environment was found in one S. enterica Virchow isolate, and the bla(CTX-M-9) gene within the In60 integron was found in the three remaining Virchow isolates. These three isolates presented indistinguishable or closely related pulsed-field gel electrophoresis patterns among themselves and also as compared with the two other bla(CTX-M-9)-containing isolates previously obtained from animals. ESBL production is an emerging mechanism of resistance in S. enterica in the two studied hospitals
Riano I., Garcia-Campello M., Saenz Y., Alvarez P., Vinue L., Lantero M., Moreno MA., Zarazaga M. y Torres C.
Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |
Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). | |
Área de Bioquímica y Biología Molecular. Universidad de La Rioja (UR). | |
Servicio de Microbiología. Complejo Hospitalario de Pontevedra. | |
Servicio de Microbiología. Hospital Universitario Central de Asturias. Servicio de Salud del Principado de Asturias (SESPA). Gobierno del Principado de Asturias. | |