Susceptibility of Listeria monocytogenes to antimicrobial peptides
FEMS Microbiology Letters publica este artículo de investigación
12 de septiembre de 2003
We assessed the susceptibility of several pathogenic and non-pathogenic Listeria species to antimicrobial peptides of animal and plant origin. Human defensins and thionins were highly inhibitory, whereas protamine, snakin and magainin showed an intermediate effect. A temperature dependence in the activity of potato defensin was observed for Listeria monocytogenes and Listeria ivanovii. PrfA* L. monocytogenes mutants, that overexpress constitutively PrfA-dependent genes, were sensitive to the peptide independently of the temperature whereas isogenic PrfA(-) derivatives were constitutively resistant. These data indicate that the thermoregulated transcription factor PrfA controls the expression of bacterial products that influence the susceptibility or resistance to some antimicrobial peptides
Lopez-Solanilla E., Gonzalez-Zorn B., Novella S., Vazquez-Boland JA. y Rodriguez-Palenzuela P.
 | Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). |
| Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). |
 | Escuela Técnica Superior de Ingenieros Agrónomos. Universidad Politécnica de Madrid (UPM). |
