Investigation published in Research in Veterinary Science

April 1^st, 2016

Recent findings suggest that use of colistin as a last resort antibiotic is seriously threatened by the rise of a new plasmid mediated mechanism of resistance (MCR-1). This work identifies, by the first time in Southern Europe, the gene mcr-1 in 9 enterobacteria from farm animals (poultry and swine), being of particular relevance its finding in 4 Salmonella enterica, 3 belonging to serovar Typhimurium and 1 to Rissen. MCR-1 was found encoded by a plasmid highly mobilizable by conjugation to the E. coli J53 strain

Quesada A., Ugarte-Ruiz M., Iglesias MR., Porrero MC., Martinez R., Florez-Cuadrado D., Campos MJ., Garcia M., Piriz S. and Dominguez L..

Detection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli and Salmonella enterica isolated from poultry and swine in Spain

Detection of plasmid mediated colistin resistance (MCR-1) in Escherichia coli and Salmonella enterica isolated from poultry and swine in Spain

	Departamento de Bioquímica, Biología Molecular y Genética. Departamento de Sanidad Animal. Red de Grupos de Investigación Recursos Faunísticos. Facultad de Veterinaria. Universidad de Extremadura (UNEX).
	Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).
	Marine and Environmental Sciences Centre (MARE). Instituto Politécnico de Leiria (IPL).