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Genetic variation in Influenza virus type A: possible consequences in molecular diagnosis

Poster presented in 5th Annual Scientific Meeting on Zoonoses Research in Europe

June 3rd, 2009

Garcia N., Perez-Sancho M., Gomez S., Alvarez J., Gonzalez S., Martinez I., Carpintero J., Diaz R. and Dominguez L.

Single-stranded RNA viruses, like Influenza virus, are considered the most widespread zoonotic emerging and reemerging pathogens. A possible explanation of this fact is the high nucleotide substitution rate of this type of viruses, which permit them a rapid adaptation to new environments and hosts, even crossing the species barrier. Nevertheless this high genetic variation is an important disadvantage not only for the treatment of the serious diseases that they can produce, but also for the diagnostic methods. Avian influenza (AI), caused by influenza virus type A, is a good example of this type of pathogens. One-step Reverse Real Time PCR (RRT-PCR) is the most widely used molecular method for AI virus detection, targeting the matrix protein gene (M-gene) that is considered well conserved among all these viruses




Participants:

Universidad ComplutenseServicio de Zoonosis Emergentes, de Baja Prevalencia y Agresivos Biológicos (NED). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).


Link to 5ª Reunión Cientí­fica Anual de Investigación de las Zoonosis en Europa





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5ª Reunión Cientí­fica Anual de Investigación de las Zoonosis en Europa


5ª Reunión Cientí­fica Anual de Investigación de las Zoonosis en Europa
Jun 3rd-6th, 2009
El Escorial
Spain

TITLE: Genetic variation in Influenza virus type A: possible consequences in molecular diagnosis


TYPE: Poster communication


AUTHORS: Garcia N., Perez-Sancho M., Gomez S., Alvarez J., Gonzalez S., Martinez I., Carpintero J., Diaz R. and Dominguez L.


VISAVET PARTICIPANTS


First
Nerea García Benzaquén
2nd
Marta Pérez Sancho
3rd
Susana Gómez Barrero
4th
Julio Álvarez Sánchez
5th
Sergio González Domínguez
6th
Irene Martínez Alares
Last
Lucas Domínguez Rodríguez

DATE: June 3rd, 2009


CITE THIS COMMUNICATION:

Garcia N., Perez-Sancho M., Gomez S., Alvarez J., Gonzalez S., Martinez I., Carpintero J., Diaz R. and Dominguez L. Genetic variation in Influenza virus type A: possible consequences in molecular diagnosis. 5ª Reunión Cientí­fica Anual de Investigación de las Zoonosis en Europa, European Network for the Prevention and Control of Zoonoses and Food Borne Diseases, El Escorial, Spain, June 3rd, 2009. (Poster communication)


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