Contact
Mycobacteria Unit
VISAVET Health Surveillance Centre
Universidad Complutense
Av. Puerta de Hierro s/n. 28040 Madrid. Spain
e-mail:
Head office phone: (+34) 913 943 992
Laboratory phone: (+34) 913 944 002
Fax: (+34) 913 943 795
MYC Unit routinely performs bacteriological and molecular diagnose of infections produced mainly by members of the Mycobacterium tuberculosis and avium complexes. Moreover, it realizes studies of molecular and epidemiological characterization. The main lines of research are to set up new technologies for the diagnosis (in vivo e in vitro) of the main principal diseases caused by mycobacteria, as well as the development of new technology for molecular characterization studies. The laboratory also designs field studies of control and eradication programs in problem situations for subsequent implementation at a national level. The laboratory also advises Animal Health Services of the Autonomous Communities, farmers and veterinarians, as well as Ministries. In addition as European Union Reference Laboratory for Bovine Tuberculosis, they provide technical and scientific support to all National Reference Laboratories (NRL) and the official veterinary services of the European Union.
Research
Research lines:
Last scientific publications:
- Monedero M., Infantes-Lorenzo JA., Moreno I., Martin AB., Macias RIR., Torano A. and Dominguez M.. Development and characterization of mouse monoclonal antibodies to eight human complement components: analysis of reactivity with orthologs of nine mammalian genera. Comparative Immunology, Microbiology and Infectious Diseases, 62:7-12. 2019. (A)
- Lorente-Leal V., Liandris E., Castellanos E., Bezos J., Dominguez L., de Juan L. and Romero B.. Validation of a Real-Time PCR for the Detection of Mycobacterium tuberculosis Complex Members in Bovine Tissue Samples. Frontiers in veterinary science, 6(61):1-9. 2019. (A)
- Infantes-Lorenzo JA., Moreno I., Roy A., Risalde MA., Balseiro A., de Juan L., Romero B., Bezos J., Puentes E., Akerstedt J., Tessema T., Gortazar C., Dominguez L. and Dominguez M.. Specificity of serological test for detection of tuberculosis in cattle, goats, sheep and pigs under different epidemiological situations. BMC Veterinary Research, 15(1):70. 2019. (A)
- Thomas J., Infantes-Lorenzo JA., Moreno I., Romero B., Garrido F., Juste R., Dominguez M., Dominguez L., Gortazar C. and Risalde MA.. A new test to detect antibodies against Mycobacterium tuberculosis complex in red deer serum. The Veterinary Journal, 15(1):70. 2019. (A)
- Infantes-Lorenzo JA., Dave D., Moreno I., Anderson P., Lesellier S., Gormley E., Dominguez L., Balseiro A., Gortazar C., Dominguez M. and Salguero FJ.. New serological platform for detecting antibodies against Mycobacterium tuberculosis complex in European badgers. Veterinary Medicine and Science, 5(1):61-69. 2019. (A)
Last PhD thesis:
- Jose Antonio Infantes Lorenzo. Immunoproteomic characterization of protein derivatives from Mycobacterium bovis, Mycobacterium avium (subspecies avium and paratuberculosis) and Corynebacterium pseudotuberculosis. Application in diagnosis. 2018.
- Carmen Casal Comendador. Diagnosis of tuberculosis in ruminants and camelids: optimization of cell-based and humoral tests. 2016. (Premio Laboratorios Ovejero, Europea)
- Yurena Navarro García. Detección, caracterización y análisis funcional de la complejidad clonal en la tuberculosis humana y bovina. 2015.
- Sabrina Rodríguez Campos. Molecular epidemiology of Mycobacterium bovis and Mycobacterium caprae in Spain. 2012. (Premio Extraordinario de Doctorado curso 2011-2012, Mención Europea)
- Javier Bezos Garrido. Tuberculosis in goats: study of immune response and contributions to diagnosis. 2011.
Outreach
Last outreach publications:
- Romero B. and Bezos J.. Ofensiva contra la tuberculosis en caprino. Tierras. Caprino, 24:60-65, OVIespaña. 2018.
- Briones V., Bezos J. and Alvarez J.. Medicina Preventiva Veterinaria: concepto y actualización. Profesión Veterinaria, 91(2018/19):20-23, Colegio Oficial de Veterinarios de Madrid. 2018.
- Roy A., Gonzalez S., Romero B., de Juan L., Dominguez L. and Bezos J.. Método de segregación como medida de control y erradicación de la tuberculosis caprina (y II). Albéitar, 215:26-28, Asís. 2018.
- Roy A., Gonzalez S., Romero B., de Juan L., Dominguez L. and Bezos J.. Método de segregación como medida de control y erradicación de la tuberculosis caprina. Albéitar, 214:20-22, Servet-Grupo Asís Biomedia S.L... 2018.
- Roy A., de Juan L., Romero B., Diez-Guerrier A., Dominguez L. and Bezos J.. Tuberculosis bovina: aspectos a considerar sobre la técnica de intradermotuberculinización y el cultivo microbiológico. AFCA, 43(2017):22-29, Agricola. 2017.
Last communications:
- de Juan L.. Diagnóstico microbiológico de la tuberculosis. Identificación del agente etiológico. Manual y normativa aplicable. Toma de muestras. Curso de actualización de la tuberculosis bovina. 2019. (Oral communication)
- Romero B.. Epidemiología molecular de la tuberculosis. Aplicación práctica de la base de datos mycoDB.es.. Curso de actualización de la tuberculosis bovina. 2019. (Oral communication)
- de Juan L.. Actividades del EU-RL for Bovine Tuberculosis. Curso de actualización de la tuberculosis bovina. 2019. (Oral communication)
- Diez-Guerrier A., Blazquez JC. y Grau A.. Problemas en la aplicación en el campo del Programa nacional. Propuestas de solución y mejora. Curso de actualización de la tuberculosis bovina. 2019. (Oral communication)
- Diez-Guerrier A., Blazquez JC. y Grau A.. El papel de veterinarios en la erradicación de la tuberculosis. Impacto del entorno socio-económico sobre el trabajo del veterinario de campo.. Curso de actualización de la tuberculosis bovina. 2019. (Oral communication)
