Comunicación presentada en 6th World Congress on Leishmaniasis

19 de mayo de 2017

Ortega-García MV., Moreno I., Garcia N., Martin AB., Navarro A., Martinez I., Garcia-Seco T., Perez-Sancho M. y Dominguez M.

Leishmania infantum is the main species implicated in Leishmaniosis in the Mediterranean basin, where the disease is endemic. Canines are the main domestic reservoirs. Recently, Leporidae have been revealed as competent reservoirs of L. infantum, being the source of infection during an important outbreak in Madrid (Spain) that involved 697 human cases from 2009 to 2016. L. infantun DNA has been detected by quantitative real-time PCR in wild rabbits and hares in two Madrid natural areas outside the outbreak area. Comparison of the strains isolated from different areas could add more knowledge about the sylvatic cycle of Leishmania spp. and PCR-RFLP can be used as a cost-effective and reliable method to achieve it.
The aims of this study are a) to characterize the L. infantum strains detected in wild Leporidae from different areas of the Community of Madrid (outbreak and non-outbreak areas); and b), to know if the L. infantum strains maintained by wild Leporidae in the outbreak area are the same as those ones found in the non-outbreak areas

	Campus La Marañosa (ITM). Instituto Nacional de Técnica Aeroespacial (INTA). Ministerio de Defensa.
	Subdirección de Sistemas Terrestres. Instituto Nacional de Técnica Aeroespacial (INTA). Ministerio de Defensa.
	Servicio de Inmunología. Centro Nacional de Microbiología (CNM). Instituto de Salud Carlos III (ISCIII).
	Servicio de Zoonosis Emergentes, de Baja Prevalencia y Agresivos Biológicos (NED). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

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