Comunicación presentada en Med-Vet-Net Association 5th International Scientific Conference (OneHealth: Zoonoses - Emerging Threats)

27 de junio de 2017

Ugarte-Ruiz M., Iglesias MR., Quijada NM., Hernandez M., Rodriguez-Lazaro D., Quesada A. y Dominguez L.

Colistin is an antibacterial agent of polymyxin class considered as a last resort treatment in human infections caused by multi resistant bacteria. However, it is regularly used in veterinary medicine against intestinal infections, specially in swine at post-weaning. It was believed that the mechanism of resistance to this antimicrobial was solely located in the bacteria chromosome, so the risk of spreading and selection of resistant bacteria was theoretical low. Conversely, in 2015 and 2016 two novel genes (mcr-1 and mcr-2) that confer resistance to this antimicrobial and were located in a high transmissible plasmid, were described. Taken together, these new mechanisms need to be included in surveillance studies as they could favor worldwide dissemination of colistin resistance in isolates of human and animal origin.

	Servicio de Zoonosis de Transmisión Alimentaria y Resistencia a Antimicrobianos (ZTA). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).
	Departamento de Bioquímica, Biología Molecular y Genética. Facultad de Veterinaria. Universidad de Extremadura (UNEX).
	Laboratorio de Biología Molecular y Microbiología. Instituto Tecnológico Agrario de Castilla y León (ITACyL).
	Departamento de Biotecnología y Ciencia de los Alimentos. Universidad de Burgos (UBU).

Enlace a Med-Vet-Net Association 5th International Scientific Conference (OneHealth: Zoonoses - Emerging Threats)