Sequence Variation in Molecular Diagnosis Target of Influenza Virus Type A
Poster presentado en International Meeting on Emerging Diseases and Surveillance 2009
13 de febrero de 2009
Garcia N., Perez-Sancho M., Alvarez J., Gonzalez S., Martinez I., Gomez S., Dominguez L. y Goyache J.
Avian Influenza (AI) is a significant infectious disease caused by Influenza virus type A, which belongs to the Family Orthomixoviridae. Its genome consists of eight single-stranded segments, negative-sense RNA, which encodes 10 or 11 proteins. The high nucleotide substitution rate for this type of viruses allows them to a rapid adaptation to new environments and hosts, even crossing the species barrier. This could explain, at least in part, the high prevalence of these agents and their definition as emerging or re-emerging pathogens. Moreover, this high genetic variability could affect molecular diagnosis methods.
Servicio de Zoonosis Emergentes, de Baja Prevalencia y Agresivos Biológicos (NED). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM). | |
Departamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM). | |
Enlace a International Meeting on Emerging Diseases and Surveillance 2009