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Lack of interference with diagnostic testing for tuberculosis in goats experimentally exposed to Corynebacterium pseudotuberculosis

Artículo de investigación publicado en The Veterinary Journal

1 de junio de 2015

It has been suggested that infection with Corynebacterium pseudotuberculosis, the pathogen responsible for caseous lymphadenitis (CLA), might interfere with diagnostic testing for tuberculosis (TB), due to antigenic similarities between this particular type of bacterium and those expressed by mycobacteria. The aim of the present study was to investigate whether experimental infection with C. pseudotuberculosis in goats impacted on TB testing, using single and comparative intradermal tuberculin (SIT and SCIT respectively) tests and interferon (IFN)-γ assay. No positive reactors were detected among the CLAaffected goats using the SIT/SCIT tests or the interferon IFN-γ assay. A proportion of goats showed inconclusive results to the SIT test and reactions to Mycobacterium avium. There was no evidence that infection with C. pseudotuberculosis interferes with diagnostic testing for TB using standard interpretation of the SIT, SCIT and IFN-γ tests




Bezos J., Casal C., Romero B., Liandris E., Sanchez-Coppel N., Vigo V., Dominguez L. y de Juan L..




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Lack of interference with diagnostic testing for tuberculosis in goats experimentally exposed to Corynebacterium pseudotuberculosis

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Lack of interference with diagnostic testing for tuberculosis in goats experimentally exposed to Corynebacterium pseudotuberculosis


Participantes:

MAEVA SERVET, S.L.MAEVA SERVET, S.L..

Universidad ComplutenseServicio de Micobacterias (MYC). Centro de Vigilancia Sanitaria Veterinaria (VISAVET). Universidad Complutense (UCM).

Gobierno de CanariasServicio de Sanidad Animal y Laboratorio. Gobierno de Canarias.

Universidad ComplutenseDepartamento de Sanidad Animal. Facultad de Veterinaria. Universidad Complutense (UCM).







The Veterinary Journal
FACTOR YEAR Q
1.693 2015

NLMID: 9706281

PMID: 25975852

ISSN: 1090-0233



TÍTULO: Lack of interference with diagnostic testing for tuberculosis in goats experimentally exposed to Corynebacterium pseudotuberculosis


REVISTA: Vet. J.


NUMERACIÓN: 205(1):113-5


AÑO: 2015


EDITORIAL: Elsevier SCI LTD


AUTORES: Bezos J., Casal C., Romero B., Liandris E., Sanchez-Coppel N., Vigo V., Dominguez L. and de Juan L..


PARTICIPANTES VISAVET


First
Javier Bezos Garrido
3rd
Beatriz Romero Martínez
7th
Lucas Domínguez Rodríguez
Last
Lucía de Juan Ferré

DOI: https://doi.org/10.1016/j.tvjl.2015.04.024


CITA ESTA PUBLICACIÓN:

Bezos J., Casal C., Romero B., Liandris E., Sanchez-Coppel N., Vigo V., Dominguez L. y de Juan L. Lack of interference with diagnostic testing for tuberculosis in goats experimentally exposed to Corynebacterium pseudotuberculosis. The Veterinary Journal. 205(1):113-5. 2015. (A). ISSN: 1090-0233. DOI: 10.1016/j.tvjl.2015.04.024


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