Contact
Foodborne Zoonoses and Antimicrobial Resistance Unit
VISAVET Health Surveillance Centre
Universidad Complutense
Av. Puerta de Hierro s/n. 28040 Madrid. Spain
e-mail:
Head office phone: (+34) 913 944 097
Fax: (+34) 913 943 795
Foodborne Zoonoses and Antimicrobial Resistance Unit became operational in 1996 based on the Veterinary Antimicrobial Resistance Surveillance Network (VAV). Nowadays, it includes the study of different food-borne zoonoses (Salmonella, Campylobacter, E. coli, Yersinia, Staphylococcus aureus ...). It is also responsible for analyzing antimicrobial resistance in zoonotic organisms, commensal bacteria of the intestinal tract or clinical isolates. The group has several lines of research on the characterization of important foodborne pathogens for Public Health and the mechanisms involved in the emergence and spread of antimicrobial resistance by using molecular tecniques as well as sequencing. It is outstanding the leadership of this group in international research projects and its collaboration with Public Administrations and companies. ZTA gives support to the Ministry of Agriculture, Fisheries, Food and Environment (MAPAMA) and the Community of Madrid developing surveillance programs for zoonotic agents.
Research
Research lines:
- Modification of intestinal microbiota, Healthy Gut (ZTA)
- Genetic characterization of Campylobacter (ZTA)
- Molecular characterization of human reservoirs potentially pathogenic Escherichia coli, animal and environmental (ZTA)
- Genetic characterization of antimicrobial resistance (ZTA)
- Genetic characterization of microorganisms populations (ZTA)
- Foodborne zoonoses in animals and meat, eggs and other products from animal origin intended for human consumption, mainly Salmonella spp. Campylobacter spp., Verotoxigenic Escherichia coli and Yersinia enterocolitica (ZTA)
- Antimicrobial resistances in pathogens, food-borne zoonotic agents and indicators (ZTA)
Last scientific publications:
- Fernandez-Garcia M., Ares M., Wedel E., Montero N., Barbas C., Rey-Stolle MF., Gonzalez-Zorn B. and García A.. Multiplatform Metabolomics Characterization Reveals Novel Metabolites and Phospholipid Compositional Rules of Haemophilus influenzae Rd KW20. International Journal of Molecualr Sciences, 24(13):11150. 2023. (A)
- Wedel E., Bernabe-Balas C., Ares M., Montero N., Santos-Lopez A., Mazel D. and Gonzalez-Zorn B.. Insertion Sequences Determine Plasmid Adaptation to New Bacterial Hosts. mBio, 14(3):e0315822. 2023. (A)
- Tiwari SK., van der Putten BCL., Fuchs TM., Vinh TN., Bootsma M., Oldenkamp R., La Ragione RM., Matamoros S., Hoa NT., Berens C., Leng J., Alvarez J., Ferrandis- Vila M., Ritchie JM., Fruth A., Schwarz S., Dominguez L., Ugarte-Ruiz M., Bethe A., Huber C., Johanns V., Stamm I., Wieler LH., Ewers C., Fivian-Hughes A., Schmitt H., Menge C., Semmler T. and Schultsz C.. Genome-wide association reveals host-specific genomic traits in Escherichia coli. BMC Biology, 21(1):76. 2023. (A)
- Delgado-Blas JF., Ovejero CM., David S., Serna C., Pulido-Vadillo M., Montero N., Aanensen DM., Abadia-Patino L. and Gonzalez-Zorn B.. Global scenario of the RmtE pan-aminoglycoside-resistance mechanism: emergence of the rmtE4 gene in South America associated with a hospital-related IncL plasmid. Microbial Genomics, 9(3). 2023. (A)
- Tast-Lathi E., Karamehmedovic N., Riedel H., Blom L., Boel J., Delibato E., Denis M., van Essen-Zanbergen A., Garcia-Fernandez A., Hendriksen R., Heydecke A., van Hoek AH., Huby T., Kwit R., Lucarelli C., Lundin K., Michelacci V., Owczarek S., Ring I., Kjeldgaard JS., Sjogren I., Skora M., Ugarte-Ruiz M., Torpdahl M., Veldman K., Ventola E., Zajac M. and Jernberg C.. One Health surveillance - cross-sectoral detection, characterisation, and notification of foodborne pathogens. Frontiers in Public Health, 11:1129083. 2023. (A)
Next PhD thesis:
- Pedro Miguela Villoldo. Identification and characterization of colistin resistant bacteria from food-producing animals in Spain. Assessment of its persistance and possible dissemination. 2023.
Last PhD thesis:
- Irene del Corral Medina. Epidemiology of Extended-Spectrum Beta-Lactamase (ESBL) and AmpC-Producing E. coli in Production Animals in Spain During the Period 2014-2018. 2023. (Doctorado Europeo)
- José Francisco Delgado Blas. Emergencia y diseminación de mecanismos de resistencia a antibióticos de último recurso en bacterias humanas, animales y ambientales. 2021. (Doctorado Europeo)
- Gabriel Moyano Ortega. Modelos animales para el estudio de la ecología de las resistencia a antibióticos: Klebsiella pneumoniae resistente a carbapenemas en ambientes nosocomiales. 2019.
- Diego Flórez Cuadrado. Genomic characterization and antimicrobial resistance of Campylobacter. 2017. (Doctorado Europeo)
- Cristina Martínez Ovejero. Mecanismos emergentes de resistencia a antibióticos en enterobacterias de origen humano, animal y ambiental. 2017. (Doctorado Internacional)
Outreach
Last outreach publications:
- Mazariegos M.. Funciones y actuaciones del Veterinario Designado. Ciencia y Tecnología en Investigación Animal. Ed. 1. Universidad de Alcalá. 2022.
- Ugarte-Ruiz M., Alvarez J., Escudero JA., Gonzalez-Zorn B., Miguela-Villoldo P., Moreno MA., Rebollada A., Rodriguez-Bertos A. and Dominguez L.. Resistencias antimicrobianas y One Health. REDRISA, Vetdivulga. 2020.
- Juez-García M., Alvarez J., Sotodosos-Carpintero M. and Ugarte-Ruiz M.. Asociación entre resistencia a antibióticos y serotipos en Salmonella de transmisión alimentaria. Revista Madrileña de Salud Pública, 4(5):1-8, Dirección General de Salud Pública de la Consejería de Sanidad de la Comunidad de Madrid. 2020.
- Gonzalez-Zorn B.. Listeriosis: así es la alarma sanitaria del verano 2019. ucm.es/otri, Universidad Complutense. 2019.
- Florez-Cuadrado D., Moreno MA., Ugarte-Ruiz M. and Dominguez L.. Antimicrobial Resistance in the Food Chain in the European Union. Biological Emerging Risks in Foods. Ed. 1. 86(5):115-136, Academic Press. 2018.
Last communications:
- Sarker J., Saba-Shirvan A., Pineau L., David C., Corvec S., Batard E., Ugarte-Ruiz M., Calvez S. y Navarro-Gonzalez N.. Antimicrobial resistance in aquatic and fecal bacteria from a Recirculating Aquaculture System and comparison with human clinical isolates. International Conference on Diseases of Fish and Shellfish. 2023. (Poster communication)
- Gonzalez-Zorn B.. RAM desde la perspectiva One Health. Respuesta One Health y Resistencia a la antibióticos: nuevos avances y nuevos retos en la lucha contra la resistencia. Cursos de verano de la Universidad Complutense. 2023. (Oral communication)
- Canton R. y Gonzalez-Zorn B.. Retos ante la resistencia a los antimicrobianos. Respuesta One Health y Resistencia a la antibióticos: nuevos avances y nuevos retos en la lucha contra la resistencia. Cursos de verano de la Universidad Complutense. 2023. (Oral communication)
- Gonzalez-Zorn B.. Resistencia a los Antimicrobianos: Objetivo 2030. Jornadas Vigilancia Sanitaria 2023: presente y futuro para 2030. 2023. (Oral communication)
- Hipolito A., Trigo da Roza F., Garcia-Pastor L., Blanco P., Carvalho A., Kieffer N., Prieto A., Vergara E., Jove T., San Millan A., Stecher B. y Escudero JA.. Caracterización de las Dinámicas Evolutivas de los Cassettes de Resistencia en Integrones. Jornadas Vigilancia Sanitaria 2023: presente y futuro para 2030. 2023. (Poster communication)
