Contact
Foodborne Zoonoses and Antimicrobial Resistance Unit
VISAVET Health Surveillance Centre
Universidad Complutense
Av. Puerta de Hierro s/n. 28040 Madrid. Spain
e-mail:
Head office phone: (+34) 913 944 097
Laboratory phone: (+34) 913 944 083
Fax: (+34) 913 943 795
Foodborne Zoonoses and Antimicrobial Resistance Unit became operational in 1996 based on the Veterinary Antimicrobial Resistance Surveillance Network (VAV). Nowadays, it includes the study of different food-borne zoonoses (Salmonella, Campylobacter, E. coli, Yersinia, Staphylococcus aureus ...). It is also responsible for analyzing antimicrobial resistance in zoonotic organisms, commensal bacteria of the intestinal tract or clinical isolates. The group has several lines of research on the characterization of important foodborne pathogens for Public Health and the mechanisms involved in the emergence and spread of antimicrobial resistance by using molecular tecniques as well as sequencing. It is outstanding the leadership of this group in international research projects and its collaboration with Public Administrations and companies. ZTA gives support to the Ministry of Agriculture, Fisheries, Food and Environment (MAPAMA) and the Community of Madrid developing surveillance programs for zoonotic agents.
Research
Research lines:
- Modification of intestinal microbiota, Healthy Gut (ZTA)
- Genetic characterization of Campylobacter (ZTA)
- Molecular characterization of human reservoirs potentially pathogenic Escherichia coli, animal and environmental (ZTA)
- Genetic characterization of antimicrobial resistance (ZTA)
- Genetic characterization of microorganisms populations (ZTA)
- Foodborne zoonoses in animals and meat, eggs and other products from animal origin intended for human consumption, mainly Salmonella spp. Campylobacter spp., Verotoxigenic Escherichia coli and Yersinia enterocolitica (ZTA)
- Antimicrobial resistances in pathogens, food-borne zoonotic agents and indicators (ZTA)
Next scientific publications:
- Rozwandowicz M., Brouwer MSM., Fischer J., Wagenaar J., Gonzalez-Zorn B., Guerra B., Mevius DJ. and Hordijk J.. Plasmids carrying antimicrobial resistance genes in Enterobacteriaceae. The Journal of Antimicrobial Chemotherapy. In Press (A)
- Rodriguez Beltran J., Hernandez Beltran JCR., de la Fuente J., Escudero JA., Fuentes Hernandez A., Craig MacLean R., Pena Miller R. and San Millan A.. Multicopy plasmids allow bacteria to escape from fitness trade-offs during evolutionary innovation. Nature ecology & evolution. In Press (A)
Last scientific publications:
- Ares M., Bernabe-Balas C., Santos-Lopez A., Baquero MR., Prasad KN., Cid D., Martin-Espada C., San Millan A. and Gonzalez-Zorn B.. PCR-Based Analysis of ColE1 Plasmids in Clinical Isolates and Metagenomic Samples Reveals Their Importance as Gene Capture Platforms. Frontiers in Microbiology, 9(469):1-15. 2018. (A)
- Hadziabdic S., Fischer J., Malorny B., Borowiak M., Guerra B., Kaesbohrer A., Gonzalez-Zorn B. and Szabo I.. In vivo transfer and microevolution of avian native IncA/C2blaNDM-1-carrying plasmid pRH-1238 during a broiler chicken infection study. Antimicrobial Agents and Chemotherapy, AAC.02128-17. 2018. (A)
- Singh S., Pathak A., Kumar A., Rahman M., Singh A., Gonzalez-Zorn B. and Prasad KN.. Emergence of chromosome borne colistin resistance gene mcr-1 in clinical isolates of Klebsiella pneumoniae from India. Antimicrobial Agents and Chemotherapy, 62(2). pii: e01885-17. 2018. (A)
- Lanza VF., Baquero F., Martinez JL., Ramos-Ruiz R., Gonzalez-Zorn B., Andremont A., Sanchez-Valenzuela A., Ehrlich SD., Kennedy S., Ruppe E., van Schaik W., Willems RJ., de la Cruz F. and Coque TM.. In-depth resistome analysis by targeted metagenomics. Microbiome, 6(1):11. 2018. (A)
- Escudero JA., Nivina A., Cambray G., Lopez-Igual R., Loot C. and Mazel D.. Recoding of synonymous genes to expand evolutionary landscapes requires control of secondary structure affecting translation. Biotechnology and bioengineering, 115(1):184-191. 2018. (A)
Last PhD thesis:
- Diego Flórez Cuadrado. Genomic characterization and antimicrobial resistance of Campylobacter. 2017.
- Cristina Martínez Ovejero. Mecanismos emergentes de resistencia a antibióticos en enterobacterias de origen humano, animal y ambiental. 2017.
- Andreas Hoefer . Regulation of the 16S rRNA resistance methyltransferases: A functional and mutational analysis of the armA 5´ UTR. 2017.
- Daniel Thomas López. Enterococcus, Salmonella y H2S: Control Remoto de la Resistencia a Antibioticos. 2017.
- Laura Carrilero Aguado. Resistance to cephalosporins in Enterococcus spp.. 2016. (Europea)
Outreach
Last outreach publications:
- Moreno MA., Florez-Cuadrado D., Ugarte-Ruiz M. and Dominguez L.. Veterinarios y antibióticos: destinados a entenderse. Profesión Veterinaria, Asís. 2018.
- Delgado-Blas JF., Matamoros BR. and Gonzalez-Zorn B.. Ecology of blaNDM and mcr-1. Journal of Laboratory and Precision Medicine, AME Publishing Company. 2017.
- Florez-Cuadrado D., Ugarte-Ruiz M., Moreno MA. and Dominguez L.. Bacterias que no temen a los antibióticos. Profesión Veterinaria, 22(88):6-13, Colegio Oficial de Veterinarios de Madrid. 2017.
- Gonzalez-Zorn B. and Moyano G.. Resistencia a los antibióticos: preguntas frecuentes. 3tres3.com, no. 2017.
- Gonzalez-Zorn B.. Antibióticos: tiempo de actuar. Suis, 134 pp. 3, Asís. 2017.
Last communications:
- Ortega Molina I.. Riesgos asociados a la presencia de Staphylococcus aureus en productos curados de cerdo. Seminarios de Investigación Doctorado en Veterinaria. 2018. (Oral communication)
- Ugarte-Ruiz M.. Zoonosis de transmisión alimentaria y su repercusión en Salud Pública. Detección y caracterización. Curso de Técnicas de Diagnóstico en Laboratorio de Sanidad Animal. 2017. (Oral communication)
- Ugarte-Ruiz M.. Zoonosis alimentarias, su importancia en Salud Pública: Salmonella y Campylobacter. Agentes zoonóticos en alimentos: Campylobacter y Salmonella. 2017. (Oral communication)
- Ugarte-Ruiz M.. Resistencias antimicrobianas: Mecanismos de resistencia y pruebas de laboratorio para detectarlas. Jornada Formativa sobre Agentes Zoonóticos y Resistencias Antimicrobianas en Alimentos. 2017. (Oral communication)
- Florez-Cuadrado D.. Los agentes zoonóticos en alimentos y su repercusión en Salud Pública. Curso Zoonosis II: zoonosis de transmisión alimentaria y resistencia antimicrobiana. 2017. (Oral communication)
